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Breast tumor segmentation is one of the key steps that helps us characterize and localize tumor regions. However, variable tumor morphology, blurred boundary, and similar intensity distributions bring challenges for accurate segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2024-01-23 Gongping Chen , Lei Li , JianXun Zhang , Yu Dai

We propose a software platform that integrates methods and tools for multi-objective parameter auto- tuning in tissue image segmentation workflows. The goal of our work is to provide an approach for improving the accuracy of nucleus/cell…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-10-09 Luis F. R. Taveira , Tahsin Kurc , Alba C. M. A. Melo , Jun Kong , Erich Bremer , Joel H. Saltz , George Teodoro

This paper introduces Tree-NET, a novel framework for medical image segmentation that leverages bottleneck feature supervision to enhance both segmentation accuracy and computational efficiency. While previous studies have employed…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Orhan Demirci , Bulent Yilmaz

In contrast to the abundant research focusing on large-scale models, the progress in lightweight semantic segmentation appears to be advancing at a comparatively slower pace. However, existing compact methods often suffer from limited…

Computer Vision and Pattern Recognition · Computer Science 2023-09-13 Guoan Xu , Wenjing Jia , Tao Wu , Ligeng Chen

Automatic instance segmentation is a problem that occurs in many biomedical applications. State-of-the-art approaches either perform semantic segmentation or refine object bounding boxes obtained from detection methods. Both suffer from…

Computer Vision and Pattern Recognition · Computer Science 2020-04-22 Long Chen , Martin Strauch , Dorit Merhof

We explore encoding brain symmetry into a neural network for a brain tumor segmentation task. A healthy human brain is symmetric at a high level of abstraction, and the high-level asymmetric parts are more likely to be tumor regions. Paying…

Computer Vision and Pattern Recognition · Computer Science 2017-11-20 Hejia Zhang , Xia Zhu , Theodore L. Willke

In this paper, we propose sparse coding-based approaches for segmentation of tumor regions from MR images. Sparse coding with data-adapted dictionaries has been successfully employed in several image recovery and vision problems. The…

Computer Vision and Pattern Recognition · Computer Science 2013-03-12 Jayaraman J. Thiagarajan , Karthikeyan Natesan Ramamurthy , Deepta Rajan , Anup Puri , David Frakes , Andreas Spanias

Highly clumped nuclei clusters captured in fluorescence in situ hybridization microscopy images are common histology entities under investigations in a wide spectrum of tissue-related biomedical investigations. Due to their large scale in…

Computer Vision and Pattern Recognition · Computer Science 2018-08-15 Xiaoyuan Guo , Hanyi Yu , Blair Rossetti , George Teodoro , Daniel Brat , Jun Kong

Recent studies have demonstrated the superiority of deep learning in medical image analysis, especially in cell instance segmentation, a fundamental step for many biological studies. However, the excellent performance of the neural networks…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Huaqian Wu , Nicolas Souedet , Caroline Jan , Cédric Clouchoux , Thierry Delzescaux

Medical image segmentation is essential for computer-assisted diagnosis and treatment planning, yet substantial anatomical variability and boundary ambiguity hinder reliable delineation of fine structures. We propose RDTE-UNet, a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Jierui Qu , Jianchun Zhao

Nuclei instance segmentation in pathological images is crucial for downstream tasks such as tumor microenvironment analysis. However, the high cost and scarcity of annotated data limit the applicability of fully supervised methods, while…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Zenan Lin , Wei Li , Jintao Chen , Zihao Wu , Wenxiong Kang , Changxin Gao , Liansheng Wang , Jin-Gang Yu

We present an efficient deep learning approach for the challenging task of tumor segmentation in multisequence MR images. In recent years, Convolutional Neural Networks (CNN) have achieved state-of-the-art performances in a large variety of…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

Boundary-based instance segmentation has drawn much attention since of its attractive efficiency. However, existing methods suffer from the difficulty in long-distance regression. In this paper, we propose a coarse-to-fine module to address…

Computer Vision and Pattern Recognition · Computer Science 2021-06-21 Feng Luo , Bin-Bin Gao , Jiangpeng Yan , Xiu Li

Radiologists often mix medical image reading strategies, including inspection of individual modalities and local image regions, using information at different locations from different images independently as well as concurrently. In this…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Xiangcen Wu , Shaheer U. Saeed , Yipei Wang , Ester Bonmati Coll , Yipeng Hu

Image segmentation plays an essential role in nuclei image analysis. Recently, the segment anything model has made a significant breakthrough in such tasks. However, the current model exists two major issues for cell segmentation: (1) the…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Qing Xu , Wenwei Kuang , Zeyu Zhang , Xueyao Bao , Haoran Chen , Wenting Duan

Semantic and instance segmentation algorithms are two general yet distinct image segmentation solutions powered by Convolution Neural Network. While semantic segmentation benefits extensively from the end-to-end training strategy, instance…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Jianfeng Cao , Hong Yan

Tremendous efforts have been made on instance segmentation but the mask quality is still not satisfactory. The boundaries of predicted instance masks are usually imprecise due to the low spatial resolution of feature maps and the imbalance…

Computer Vision and Pattern Recognition · Computer Science 2021-04-13 Chufeng Tang , Hang Chen , Xiao Li , Jianmin Li , Zhaoxiang Zhang , Xiaolin Hu

Precise segmentation of brain tumors, particularly contrast-enhancing regions visible in post-contrast MRI (areas highlighted by contrast agent injection), is crucial for accurate clinical diagnosis and treatment planning but remains…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Minye Shao , Zeyu Wang , Haoran Duan , Yawen Huang , Bing Zhai , Shizheng Wang , Yang Long , Yefeng Zheng

Accurate segmentation is crucial for clinical applications, but existing models often assume fixed, high-resolution inputs and degrade significantly when faced with lower-resolution data in real-world scenarios. To address this limitation,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Simon Winther Albertsen , Hjalte Svaneborg Bjørnstrup , Mostafa Mehdipour Ghazi

Breast ultrasound imaging is a valuable tool for early breast cancer detection, but automated tumor segmentation is challenging due to inherent noise, variations in scale of lesions, and fuzzy boundaries. To address these challenges, we…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Muhammad Azeem Aslam , Asim Naveed , Nisar Ahmed