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This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Yuxin Cui , Guiying Zhang , Zhonghao Liu , Zheng Xiong , Jianjun Hu

The grade of clear cell renal cell carcinoma (ccRCC) is a critical prognostic factor, making ccRCC nuclei grading a crucial task in RCC pathology analysis. Computer-aided nuclei grading aims to improve pathologists' work efficiency while…

Image and Video Processing · Electrical Eng. & Systems 2021-06-22 Zeyu Gao , Jiangbo Shi , Xianli Zhang , Yang Li , Haichuan Zhang , Jialun Wu , Chunbao Wang , Deyu Meng , Chen Li

Separating overlapped nuclei is a major challenge in histopathology image analysis. Recently published approaches have achieved promising overall performance on nuclei segmentation; however, their performance on separating overlapped nuclei…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Haotian Wang , Aleksandar Vakanski , Changfa Shi , Min Xian

The accurate segmentation of medical images is a crucial step in obtaining reliable morphological statistics. However, training a deep neural network for this task requires a large amount of labeled data to ensure high-accuracy results. To…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Xianjun Han , Qianqian Chen , Zhaoyang Xie , Xuejun Li , Hongyu Yang

Kidney structures segmentation is a crucial yet challenging task in the computer-aided diagnosis of surgery-based renal cancer. Although numerous deep learning models have achieved remarkable success in many medical image segmentation…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Shishuai Hu , Yiwen Ye , Zehui Liao , Yong Xia

Tumor segmentation from multi-modal brain MRI images is a challenging task due to the limited samples, high variance in shapes and uneven distribution of tumor morphology. The performance of automated medical image segmentation has been…

Image and Video Processing · Electrical Eng. & Systems 2024-02-13 Tianyi Ren , Ethan Honey , Harshitha Rebala , Abhishek Sharma , Agamdeep Chopra , Mehmet Kurt

We present a conceptually simple framework for object instance segmentation called Contour Proposal Network (CPN), which detects possibly overlapping objects in an image while simultaneously fitting closed object contours using an…

Computer Vision and Pattern Recognition · Computer Science 2021-04-09 Eric Upschulte , Stefan Harmeling , Katrin Amunts , Timo Dickscheid

Machine-based brain tumor segmentation can help doctors make better diagnoses. However, the complex structure of brain tumors and expensive pixel-level annotations present challenges for automatic tumor segmentation. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2024-08-05 Ruitao Xie , Limai Jiang , Xiaoxi He , Yi Pan , Yunpeng Cai

Accurate segmentation of different sub-regions of gliomas including peritumoral edema, necrotic core, enhancing and non-enhancing tumor core from multimodal MRI scans has important clinical relevance in diagnosis, prognosis and treatment of…

Computer Vision and Pattern Recognition · Computer Science 2018-12-05 Xue Feng , Nicholas Tustison , Craig Meyer

Boundary representation (B-rep) models are the standard way 3D shapes are described in Computer-Aided Design (CAD) applications. They combine lightweight parametric curves and surfaces with topological information which connects the…

In this paper, we propose an automatic brain tumor segmentation approach (e.g., PixelNet) using a pixel-level convolutional neural network (CNN). The model extracts feature from multiple convolutional layers and concatenate them to form a…

Image and Video Processing · Electrical Eng. & Systems 2022-04-26 Mobarakol Islam , Hongliang Ren

Boundary incompleteness raises great challenges to automatic prostate segmentation in ultrasound images. Shape prior can provide strong guidance in estimating the missing boundary, but traditional shape models often suffer from hand-crafted…

Computer Vision and Pattern Recognition · Computer Science 2016-12-07 Xin Yang , Lequan Yu , Lingyun Wu , Yi Wang , Dong Ni , Jing Qin , Pheng-Ann Heng

Nuclei segmentation and classification provide an essential basis for tumor immune microenvironment analysis. The previous nuclei segmentation and classification models require splitting large images into smaller patches for training,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Ye Zhang , Zijie Fang , Yifeng Wang , Lingbo Zhang , Xianchao Guan , Yongbing Zhang

Automated diagnosis with artificial intelligence has emerged as a promising area in the realm of medical imaging, while the interpretability of the introduced deep neural networks still remains an urgent concern. Although contemporary…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Binghua Li , Jie Mao , Zhe Sun , Chao Li , Qibin Zhao , Toshihisa Tanaka

The state-of-the-art in semantic segmentation is currently represented by fully convolutional networks (FCNs). However, FCNs use large receptive fields and many pooling layers, both of which cause blurring and low spatial resolution in the…

Computer Vision and Pattern Recognition · Computer Science 2016-05-26 Gedas Bertasius , Jianbo Shi , Lorenzo Torresani

Although deep models have greatly improved the accuracy and robustness of image segmentation, obtaining segmentation results with highly accurate boundaries and fine structures is still a challenging problem. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2021-05-12 Xuebin Qin , Deng-Ping Fan , Chenyang Huang , Cyril Diagne , Zichen Zhang , Adrià Cabeza Sant'Anna , Albert Suàrez , Martin Jagersand , Ling Shao

In this work we introduce a new Bounding-Box Free Network (BBFNet) for panoptic segmentation. Panoptic segmentation is an ideal problem for proposal-free methods as it already requires per-pixel semantic class labels. We use this…

Computer Vision and Pattern Recognition · Computer Science 2020-07-28 Ujwal Bonde , Pablo F. Alcantarilla , Stefan Leutenegger

One of the main requirements of tumor extraction is the annotation and segmentation of tumor boundaries correctly. For this purpose, we present a threefold deep learning architecture. First classifiers are implemented with a deep…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Shanaka Ramesh Gunasekara , H. N. T. K. Kaldera , Maheshi B. Dissanayake

Simultaneous segmentation and classification of nuclei in digital histology play an essential role in computer-assisted cancer diagnosis; however, it remains challenging. The highest achieved binary and multi-class Panoptic Quality (PQ)…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Ibtihaj Ahmad , Syed Muhammad Israr , Zain Ul Islam

Gland segmentation is a critical step to quantitatively assess the morphology of glands in histopathology image analysis. However, it is challenging to separate densely clustered glands accurately. Existing deep learning-based approaches…

Image and Video Processing · Electrical Eng. & Systems 2021-10-28 Haotian Wang , Min Xian , Aleksandar Vakanski