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We numerically investigate the influence of flow development on secondary flow patterns and subsequent wall shear stress distributions in a curved artery model, and we compute vascular metrics commonly used to assess variations in blood…

Fluid Dynamics · Physics 2022-09-20 Christopher Cox , Michael W. Plesniak

In this study OpenFOAM 4.4.2 was used to investigate flow inside the coronary artery of the heart. This step is the first step of our future project, which is to include conjugate heat transfer of the heart with three main coronary…

Medical Physics · Physics 2021-07-19 Mohammadreza Nezamirad , Nasim Sabetpour , Azadeh Yazdi , Amirmasoud Hamedi

One-dimensional blood flow model accuracy has been verified in many studies. This work is about introducing gravity into a one-dimensional model. For this purpose, gravitational force was introduced into the existing model. The boundary…

Fluid Dynamics · Physics 2023-06-27 Oleg Shramko , Andrey Svitenkov , Pavel Zun

Blood Pressure (BP) is a biological signal related to the cardiovascular system that inevitably is affected by ageing. Moreover, it is also influenced by the presence of cardiovascular risk factors. To evaluate how the relationship be-tween…

Signal Processing · Electrical Eng. & Systems 2020-11-24 Giulia Silveri , Lorenzo Pascazio , Milos Ajcevic , Aleksandar Miladinovic , Agostino Accardo1

The variation of blood flow characteristics caused by the probe pressure during noninvasive studies is of particular interest within the context of fundamental and applied research. It has been shown previously that the weak local pressure…

Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear. Aim of the…

Medical Physics · Physics 2019-04-17 Stefania Scarsoglio , Caterina Gallo , Andrea Saglietto , Luca Ridolfi , Matteo Anselmino

We numerically investigate the effect of entrance condition on the spatial and temporal evolution of multiple three-dimensional vortex pairs and wall shear stress distribution in a curved artery model. We perform this study using a…

Fluid Dynamics · Physics 2021-11-10 Christopher Cox , Michael W. Plesniak

Continuous and noninvasive monitoring of blood pressure has numerous clinical and fitness applications. Current methods of continuous measurement of blood pressure are either invasive and/or require expensive equipment. Therefore, we…

Signal Processing · Electrical Eng. & Systems 2018-11-16 Armin Soltan Zadi , Raichel Alex , Rong Zhang , Donald E. Watenpaugh , Khosrow Behbehani

Hypertension is one of the most common age-related chronic diseases and by predisposing individuals for heart failure, stroke and kidney disease, it is a major source of morbidity and mortality. Its etiology remains enigmatic despite…

Tissues and Organs · Quantitative Biology 2015-06-15 Klas H. Pettersen , Scott M. Bugenhagen , Javaid Nauman , Daniel A. Beard , Stig W. Omholt

There are more than 300,000 heart valves implanted annually worldwide with about 50% of them being mechanical valves. The heart valve replacement is often a common treatment for severe valvular disease. However, valves may dysfunction…

Fluid Dynamics · Physics 2018-03-12 Fardin Khalili , Peshala T. Gamage , Hansen Mansy

Bileaflet mechanical heart valves have one of the most successful valve designs for more than 30 years. These valves are often used for aortic valve replacement, where the geometry of the aortic root sinuses may vary due to valvular disease…

Fluid Dynamics · Physics 2018-03-12 Fardin Khalili , Peshala P. T. Gamage , Hansen A. Mansy

Mechanical heart valve replacement is the preferred alternative in younger patients with severe symptomatic aortic valve disease. However, thrombus and pannus formations are common complications associated with bileaflet mechanical heart…

Medical Physics · Physics 2019-11-14 Ahmed Darwish , Giuseppe Di Labbio , Wael Saleh , Othman Smadi , Lyes Kadem

An improved understanding of how vortices develop and propagate under pulsatile flow can shed important light on the mixing and transport processes including the transition to turbulent regime occurring in such systems. For example, the…

Fluid Dynamics · Physics 2019-12-13 Nicasio Barrere , Javier Brum , Alexandre L'Her , Gustavo L. Sarasúa , Cecilia Cabeza

We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…

Fluid Dynamics · Physics 2008-11-11 Renat A. Sultanov , Dennis Guster

We introduce an innovative lumped-parameter model of the aortic valve, designed to efficiently simulate the impact of valve dynamics on blood flow. Our reduced model includes the elastic effects associated with the leaflets' curvature and…

Numerical Analysis · Mathematics 2025-04-15 Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

Using a three-compartment model of blood pressure dynamics, we analyze theoretically the short term cardiovascular variability: how the respiratory-related blood pressure fluctuations are buffered by appropriate heart rate changes: i.e. the…

Medical Physics · Physics 2010-07-15 Teodor Buchner , Jan Żebrowski , Grzegorz Gielerak

The influence of hypertension on low-density lipoproteins intake into the arterial wall is an important factor for understanding mechanisms of atherosclerosis. It has been experimentally observed that the increased pressure leads to the…

Biological Physics · Physics 2016-04-14 Katarzyna Jesionek , Aleksandra Slapik , Marcin Kostur

We experimentally and numerically investigate the flow of a Newtonian fluid through a constricted geometry for Reynolds numbers in the range $0.1 - 100$. The major aim is to study non-linear inertia effects at larger Reynolds numbers (>10)…

In this paper, effects of heat and mass transfer on two-phase pulsatile blood flow through a narrowed stenosed artery with radiation and the chemical reaction have been investigated. A vertical artery is assumed in which magnetic field is…

Fluid Dynamics · Physics 2018-07-27 Bhavya Tripathi , Bhupendra Kumar Sharma , Madhu Sharma

Inertial pumping is a promising new method of moving fluids through microchannels but many of its properties remain unexplored. In this work, inertial flow rates are investigated for different channel lengths, operating temperatures, and…

Fluid Dynamics · Physics 2022-02-03 Pavel E. Kornilovitch , Tyler Cochell , Alexander N. Govyadinov
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