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We consider a generic class of gene circuits affected by nonlinear extrinsic noise. To address this nonlinearity we introduce a general perturbative methodology based on assuming timescale separation between noise and genes dynamics, with…

Molecular Networks · Quantitative Biology 2023-05-10 Gerardo Aquino , Andrea Rocco

We study the statistical physics of a surprising phenomenon arising in large networks of excitable elements in response to noise: while at low noise, solutions remain in the vicinity of the resting state and large-noise solutions show…

Adaptation and Self-Organizing Systems · Physics 2020-04-01 Jonathan D. Touboul , Charlotte Piette , Laurent Venance , G. Bard Ermentrout

In neurosciences, the brain processes information via the firing patterns of connected neurons operating across a spectrum of frequencies. To better understand the effects of these frequencies in the neuron dynamics, we have simulated a…

Neurons and Cognition · Quantitative Biology 2025-11-21 Gabriel Marghoti , Thiago L. Prado , Miguel A. F. Sanjuán , Sergio R. Lopes

In recurrent neural networks (RNNs) used to model biological neural networks, noise is typically introduced during training to emulate biological variability and regularize learning. The expectation is that removing the noise at test time…

Neural and Evolutionary Computing · Computer Science 2026-01-09 Noah Eckstein , Manoj Srinivasan

Spontaneous cortical population activity exhibits a multitude of oscillatory patterns, which often display synchrony during slow-wave sleep or under certain anesthetics and stay asynchronous during quiet wakefulness. The mechanisms behind…

Neurons and Cognition · Quantitative Biology 2018-06-20 Rodrigo F. O. Pena , Michael A. Zaks , Antonio C. Roque

Integrate and fire oscillators are widely used to model the generation of action potentials in neurons. In this paper, we discuss small noise asymptotic results for a class of stochastic integrate and fire oscillators (SIFs) in which the…

Probability · Mathematics 2009-07-22 Peter Baxendale , John Mayberry

A recent study on the effect of colored driving noise on the escape from a metastable state derives an analytic expression of the transfer function of the leaky integrate-and-fire neuron model subject to colored noise. Here we present an…

Neurons and Cognition · Quantitative Biology 2015-10-14 Jannis Schuecker , Markus Diesmann , Moritz Helias

Neurons in the brain continuously process the barrage of sensory inputs they receive from the environment. A wide array of experimental work has shown that the collective activity of neural populations encodes and processes this constant…

Neurons and Cognition · Quantitative Biology 2025-10-30 Siddharth Paliwal , Gabriel Koch Ocker , Braden A. W. Brinkman

We analyze the effects of noise on the traveling wave dynamics in neural fields. The noise influences the dynamics on two scales: first, it causes fluctuations in the wave profile, and second, it causes a random shift in the phase of the…

Probability · Mathematics 2015-08-06 Eva Lang

In this manuscript we analyze the collective behavior of mean-field limits of large-scale, spatially extended stochastic neuronal networks with delays. Rigorously, the asymptotic regime of such systems is characterized by a very intricate…

Dynamical Systems · Mathematics 2017-02-21 Jonathan Touboul

Trial-to-trial variability is an essential feature of neural responses, but its source is a subject of active debate. Response variability (Mast and Victor, 1991; Arieli et al., 1995 & 1996; Anderson et al., 2000 & 2001; Kenet et al., 2003;…

Neurons and Cognition · Quantitative Biology 2010-08-04 L F Abbott , Kanaka Rajan , Haim Sompolinsky

In recent years, more and more researchers in the field of neural networks are interested in creating hardware implementations where neurons and the connection between them are realized physically. The physical implementation of ANN…

Neural and Evolutionary Computing · Computer Science 2023-07-24 V. M. Moskvitin , N. Semenova

The functional significance of correlations between action potentials of neurons is still a matter of vivid debates. In particular it is presently unclear how much synchrony is caused by afferent synchronized events and how much is…

Neurons and Cognition · Quantitative Biology 2013-04-09 Matthias Schultze-Kraft , Markus Diesmann , Sonja Grün , Moritz Helias

Living systems implement and execute an extraordinary plethora of computational tasks. The inherent degree of large scale coordination emerges as a global property, from the intricate sea of microscopic interactions. The brain, with its…

Disordered Systems and Neural Networks · Physics 2018-01-03 Duccio Fanelli , Francesco Ginelli , Roberto Livi , Niccolò Zagli , Clement Zankoc

We analyze order-disorder phase transitions driven by noise that occur in two kinds of network models closely related to the self-propelled model proposed by Vicsek et. al. to describe the collective motion of groups of organisms…

Disordered Systems and Neural Networks · Physics 2008-02-27 Jaime A. Pimentel , Maximino Aldana , Cristián Huepe , Hernán Larralde

We demonstrate the existence of noise-induced periodicity (coherence resonance) in both a discrete-time model and a continuous-time model of an excitable neuron. In particular, we show that the effects of noise added to the fast and slow…

Neurons and Cognition · Quantitative Biology 2009-11-10 Robert C. Hilborn , Rebecca J. Erwin

Excessively high, neural synchronisation has been associated with epileptic seizures, one of the most common brain diseases worldwide. A better understanding of neural synchronisation mechanisms can thus help control or even treat epilepsy.…

The seemingly stochastic transient dynamics of neocortical circuits observed in vivo have been hypothesized to represent a signature of ongoing stochastic inference. In vitro neurons, on the other hand, exhibit a highly deterministic…

Neurons and Cognition · Quantitative Biology 2017-03-14 Mihai A. Petrovici , Johannes Bill , Ilja Bytschok , Johannes Schemmel , Karlheinz Meier

Various classes of neurons alternate between high-frequency discharges and silent intervals. This phenomenon is called burst firing. To analyze burst activity in an insect system, grasshopper auditory receptor neurons were recorded in vivo…

Neurons and Cognition · Quantitative Biology 2008-07-17 Hugo G. Eyherabide , Ariel Rokem , Andreas V. M. Herz , Ines Samengo

Noise usually has an unwelcome influence on system performance. For instance, noise inevitably affects the low-frequency mechanical freedom in optomechanical experiments. However, we investigate here the beneficial effects of thermal noise…

Quantum Physics · Physics 2018-12-26 Danying Yu , Min Xie , Yanbei Cheng , Bixuan Fan