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Organisms are nonequilibrium, stationary systems self-organized via spontaneous symmetry breaking and undergoing metabolic cycles with broken detailed balance in the environment. The thermodynamic free-energy principle describes an…

Neurons and Cognition · Quantitative Biology 2022-11-24 Chang Sub Kim

In this PhD thesis, we explore and apply methods inspired by the free energy principle to two important areas in machine learning and neuroscience. The free energy principle is a general mathematical theory of the necessary…

Artificial Intelligence · Computer Science 2021-08-31 Beren Millidge

The free energy principle has been proposed as a unifying account of brain function. It is closely related, and in some cases subsumes, earlier unifying ideas such as Bayesian inference, predictive coding, and active learning. This article…

Neurons and Cognition · Quantitative Biology 2022-11-30 Samuel J. Gershman

The Free-Energy-Principle (FEP) is an influential and controversial theory which postulates a deep and powerful connection between the stochastic thermodynamics of self-organization and learning through variational inference. Specifically,…

Artificial Intelligence · Computer Science 2021-10-05 Beren Millidge , Anil Seth , Christopher L Buckley

The concept of free energy has its origins in 19th century thermodynamics, but has recently found its way into the behavioral and neural sciences, where it has been promoted for its wide applicability and has even been suggested as a…

Neurons and Cognition · Quantitative Biology 2020-12-08 Sebastian Gottwald , Daniel A. Braun

Bayesian mechanics provides a framework that addresses dynamical systems that can be conceptualised as Bayesian inference. However, elucidating the requisite generative models is essential for empirical applications to realistic…

Neurons and Cognition · Quantitative Biology 2024-12-02 Takuya Isomura

The brain is a biological system comprising nerve cells and orchestrates its embodied agent's perception, behavior, and learning in the dynamic environment. The free energy principle (FEP) advocated by Karl Friston explicates the local,…

Neurons and Cognition · Quantitative Biology 2024-10-07 Chang Sub Kim

This paper provides a perspective on applying the concepts of information thermodynamics, developed recently in non-equilibrium statistical physics, to problems in theoretical neuroscience. Historically, information and energy in…

Neurons and Cognition · Quantitative Biology 2024-09-27 Jan Karbowski

We develop a novel data-driven approach to the inverse problem of classical statistical mechanics: given experimental data on the collective motion of a classical many-body system, how does one characterise the free energy landscape of that…

Statistical Mechanics · Physics 2022-03-01 Peter Yatsyshin , Serafim Kalliadasis , Andrew B. Duncan

The aim of this paper is twofold: (1) to assess whether the construct of neural representations plays an explanatory role under the variational free-energy principle and its corollary process theory, active inference; and (2) if so, to…

Neurons and Cognition · Quantitative Biology 2023-07-19 Maxwell Ramstead , Karl Friston , Ines Hipolito

The 'free energy principle' (FEP) has been suggested to provide a unified theory of the brain, integrating data and theory relating to action, perception, and learning. The theory and implementation of the FEP combines insights from…

Neurons and Cognition · Quantitative Biology 2017-05-26 Christopher L. Buckley , Chang Sub Kim , Simon McGregor , Anil K. Seth

Consider a population of organisms that harvest free energy from their environment to reproduce. This paper shows that if the organisms' reproductive rates are proportional to the amount of physical free energy that they can convert into…

Populations and Evolution · Quantitative Biology 2025-11-25 Seth Lloyd

The free energy principle (FEP) in the neurosciences stipulates that all viable agents induce and minimize informational free energy in the brain to fit their environmental niche. In this study, we continue our effort to make the FEP a more…

Neurons and Cognition · Quantitative Biology 2021-01-25 Chang Sub Kim

Biological synaptic transmission is unreliable, and this unreliability likely degrades neural circuit performance. While there are biophysical mechanisms that can increase reliability, for instance by increasing vesicle release probability,…

Neurons and Cognition · Quantitative Biology 2024-07-02 James Malkin , Cian O'Donnell , Conor Houghton , Laurence Aitchison

A popular theory of perceptual processing holds that the brain learns both a generative model of the world and a paired recognition model using variational Bayesian inference. Most hypotheses of how the brain might learn these models assume…

Neurons and Cognition · Quantitative Biology 2021-06-01 Ari S. Benjamin , Konrad P. Kording

We show how any system with morphological degrees of freedom and locally limited free energy will, under the constraints of the free energy principle, evolve toward a neuromorphic morphology that supports hierarchical computations in which…

Quantum Physics · Physics 2023-02-28 Chris Fields , Karl Friston , James F. Glazebrook , Michael Levin , Antonino Marcianò

This thesis focuses on three fundamental aspects of biological systems; namely, entropy production, Bayesian mechanics, and the free-energy principle. The contributions are threefold: 1) We compute the entropy production for a greater class…

Mathematical Physics · Physics 2024-10-16 Lancelot Da Costa

This paper provides a concise description of the free energy principle, starting from a formulation of random dynamical systems in terms of a Langevin equation and ending with a Bayesian mechanics that can be read as a physics of sentience.…

We formulate the computational processes of perception in the framework of the principle of least action by postulating the theoretical action as a time integral of the free energy in the brain sciences. The free energy principle is…

Neurons and Cognition · Quantitative Biology 2019-02-21 Chang Sub Kim

The Free Energy Principle (FEP) states that under suitable conditions of weak coupling, random dynamical systems with sufficient degrees of freedom will behave so as to minimize an upper bound, formalized as a variational free energy, on…

Quantum Physics · Physics 2022-07-21 Chris Fields , Karl Friston , James F. Glazebrook , Michael Levin
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