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Recent masked diffusion models (MDMs) have shown competitive performance compared to autoregressive models (ARMs) for language modeling. While most literature has focused on performance enhancing sampling procedures, efficient sampling from…

Machine Learning · Computer Science 2025-06-02 Heli Ben-Hamu , Itai Gat , Daniel Severo , Niklas Nolte , Brian Karrer

Gene transcription is a highly stochastic and dynamic process. As a result, the mRNA copy number of a given gene is heterogeneous both between cells and across time. We present a framework to model gene transcription in populations of cells…

Quantitative Methods · Quantitative Biology 2017-01-10 Justine Dattani , Mauricio Barahona

In this paper, we study the maximum entropy sampling problem (MESP) and its variants. MESP seeks to identify a small subset of variables that maximizes the determinant of a covariance submatrix, and is a fundamental model in optimal…

Optimization and Control · Mathematics 2026-04-14 Lingqing Shen , Fatma Kılınç-Karzan

Recently discovered simple quantitative relations, known as bacterial growth laws, hint on the existence of simple underlying principles at the heart of bacterial growth. In this work, we provide a unifying picture on how these known…

Molecular Networks · Quantitative Biology 2021-04-27 Anjan Roy , Dotan Goberman , Rami Pugatch

Non-coding RNA sequences play a great role in controlling a number of cellular functions, thus raising the need to understand their complex conformational dynamics in quantitative detail. In this perspective, we first show that single…

Biomolecules · Quantitative Biology 2012-11-29 Jong-Chin Lin , Changbong Hyeon , D. Thirumalai

regulation largely unexplored, in part due to methodological limitations. Indeed, we review evidence demonstrating that commonly used methods, such as transcriptomics, are inadequate because the variability in mRNAs coding for ribosomal…

Quantitative Methods · Quantitative Biology 2020-09-01 Aleksandra A. Petelski , Nikolai Slavov

The rational covariance extension problem (RCEP) is an important problem in systems and control occurring in such diverse fields as control, estimation, system identification, and signal and image processing, leading to many fundamental…

Optimization and Control · Mathematics 2018-02-07 Axel Ringh , Johan Karlsson , Anders Lindquist

Neuro-encoded expression programming(NEEP) that aims to offer a novel continuous representation of combinatorial encoding for genetic programming methods is proposed in this paper. Genetic programming with linear representation uses…

Neural and Evolutionary Computing · Computer Science 2021-04-12 Aftab Anjum , Fengyang Sun , Lin Wang , Jeff Orchard

In this work, we present the multi-point probability distribution of the totally asymmetric simple exclusion process (TASEP) in a half-space, starting from a general deterministic initial condition. More precisely, let $h(t,x)$ denote the…

Probability · Mathematics 2025-08-08 Xincheng Zhang

The multispecies asymmetric simple exclusion process (mASEP) is a Markov chain in which particles of different species hop along a one-dimensional lattice. This paper studies the doubly asymmetric simple exclusion process…

Combinatorics · Mathematics 2024-03-12 Yuhan Jiang

The Ribosome Flow Model (RFM) describes the unidirectional movement of interacting particles along a one-dimensional chain of sites. As a site becomes fuller, the effective entry rate into this site decreases. The RFM has been used to model…

Networking and Internet Architecture · Computer Science 2015-08-26 Yoram Zarai , Oz Mendel , Michael Margaliot

How cost-effectively can we elicit strong reasoning in language models by leveraging their underlying representations? We answer this question with Resa, a family of 1.5B reasoning models trained via a novel and efficient sparse autoencoder…

Computation and Language · Computer Science 2025-06-17 Shangshang Wang , Julian Asilis , Ömer Faruk Akgül , Enes Burak Bilgin , Ollie Liu , Deqing Fu , Willie Neiswanger

The resources in a cell are finite, which implies that the various components of the cell must compete for resources. One such resource is the ribosomes used during translation to create proteins. Motivated by this example, we explore this…

Statistical Mechanics · Physics 2012-06-15 L. Jonathan Cook , R. K. P. Zia

We study the spectrum of the Markov matrix of the totally asymmetric exclusion process (TASEP) on a one-dimensional periodic lattice at ARBITRARY filling. Although the system does not possess obvious symmetries except translation…

Statistical Mechanics · Physics 2009-11-10 O. Golinelli , K. Mallick

We propose a simple yet robust stochastic answer network (SAN) that simulates multi-step reasoning in machine reading comprehension. Compared to previous work such as ReasoNet which used reinforcement learning to determine the number of…

Computation and Language · Computer Science 2018-05-16 Xiaodong Liu , Yelong Shen , Kevin Duh , Jianfeng Gao

In a random ray method of neutral particle transport simulation, each iteration begins by sampling a set of rays before proceeding to solve the characteristic transport equation along the linear paths the rays follow. Historically,…

Computational Physics · Physics 2025-01-13 Samuel Pasmann , John Tramm

This thesis presents a broad-coverage probabilistic top-down parser, and its application to the problem of language modeling for speech recognition. The parser builds fully connected derivations incrementally, in a single pass from…

Computation and Language · Computer Science 2007-05-23 Brian Roark

The letter proposes an adaptive model reduction approach based on tensor decomposition to speed up time-domain power system simulation. Taylor series expansion of a power system dynamic model is calculated around multiple equilibria…

Systems and Control · Computer Science 2019-04-02 Denis Osipov , Kai Sun

The dynamics of an asymmetric tracer in the symmetric simple exclusion process (SEP) is mapped, in the continuous scaling limit, to the local current through the origin in the zero-range process (ZRP) with a biased bond. This allows us to…

Statistical Mechanics · Physics 2022-11-23 Rahul Dandekar , Kirone Mallick

Response-adaptive randomization (RAR) methods can be used to adapt randomization probabilities based on accumulating data, aiming to increase the probability of allocating patients to effective treatments. A popular RAR method is Thompson…

Methodology · Statistics 2026-03-10 Samuel Pawel , Leonhard Held