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The discovery of important biomarkers is a significant step towards understanding the molecular mechanisms of carcinogenesis; enabling accurate diagnosis for, and prognosis of, a certain cancer type. Before recommending any diagnosis,…

Quantitative Methods · Quantitative Biology 2019-09-11 Md. Rezaul Karim , Michael Cochez , Oya Beyan , Stefan Decker , Christoph Lange

Language Models (LMs) continue to advance, improving response quality and coherence. Given Internet-scale training datasets, LMs have likely encountered much of what users may ask them to generate in some form during their training. A…

Artificial Intelligence · Computer Science 2026-01-27 Michael Majurski , Cynthia Matuszek

BACKGROUND: Breast cancer has emerged as one of the most prevalent cancers among women leading to a high mortality rate. Due to the heterogeneous nature of breast cancer, there is a need to identify differentially expressed genes associated…

Machine Learning · Computer Science 2021-11-30 Sheetal Rajpal , Ankit Rajpal , Manoj Agarwal , Naveen Kumar

In this paper, we present a novel integrated approach for keyphrase generation (KG). Unlike previous works which are purely extractive or generative, we first propose a new multi-task learning framework that jointly learns an extractive…

Computation and Language · Computer Science 2019-04-09 Wang Chen , Hou Pong Chan , Piji Li , Lidong Bing , Irwin King

Although somatic mutations are the main contributor to cancer, underlying germline alterations may increase the risk of cancer, mold the somatic alteration landscape and cooperate with acquired mutations to promote the tumor onset and/or…

Quantitative Methods · Quantitative Biology 2016-11-01 Jorge Fernandez-de-Cossio , Yasser Perera

As the development of the encoder-decoder architecture, researchers are able to study the text generation tasks with broader types of data. Among them, KB-to-text aims at converting a set of knowledge triples into human readable sentences.…

Computation and Language · Computer Science 2022-09-27 Zihao Fu , Yijiang River Dong , Lidong Bing , Wai Lam

A variety of genome-wide profiling techniques are available to probe complementary aspects of genome structure and function. Integrative analysis of heterogeneous data sources can reveal higher-level interactions that cannot be detected…

Computational Engineering, Finance, and Science · Computer Science 2012-03-23 Leo Lahti , Martin Schäfer , Hans-Ulrich Klein , Silvio Bicciato , Martin Dugas

Gene selection plays a pivotal role in oncology research for improving outcome prediction accuracy and facilitating cost-effective genomic profiling for cancer patients. This paper introduces two gene selection strategies for deep…

Genomics · Quantitative Biology 2024-03-05 Akhila Krishna , Ravi Kant Gupta , Pranav Jeevan , Amit Sethi

We study the problem of generating keyphrases that summarize the key points for a given document. While sequence-to-sequence (seq2seq) models have achieved remarkable performance on this task (Meng et al., 2017), model training often relies…

Computation and Language · Computer Science 2019-09-09 Hai Ye , Lu Wang

Conventionally, the radiologist prepares the diagnosis notes and shares them with the transcriptionist. Then the transcriptionist prepares a preliminary formatted report referring to the notes, and finally, the radiologist reviews the…

Computation and Language · Computer Science 2022-06-15 Kaveri Kale , Pushpak Bhattacharyya , Aditya Shetty , Milind Gune , Kush Shrivastava , Rustom Lawyer , Spriha Biswas

The prediction of cancer prognosis and metastatic potential immediately after the initial diagnoses is a major challenge in current clinical research. The relevance of such a signature is clear, as it will free many patients from the agony…

Applications · Statistics 2017-10-17 Royi Jacobovic

Evidence-based medicine, the practice in which healthcare professionals refer to the best available evidence when making decisions, forms the foundation of modern healthcare. However, it relies on labour-intensive systematic reviews, where…

Computation and Language · Computer Science 2021-12-13 Jetsun Whitton , Anthony Hunter

Cancer is a complex disease, the understanding and treatment of which are being aided through increases in the volume of collected data and in the scale of deployed computing power. Consequently, there is a growing need for the development…

Knowledge graphs can represent information about the real-world using entities and their relations in a structured and semantically rich manner and they enable a variety of downstream applications such as question-answering, recommendation…

Computation and Language · Computer Science 2023-05-16 Hanieh Khorashadizadeh , Nandana Mihindukulasooriya , Sanju Tiwari , Jinghua Groppe , Sven Groppe

Understanding the molecular processes that drive cellular life is a fundamental question in biological research. Ambitious programs have gathered a number of molecular datasets on large populations. To decipher the complex cellular…

Genomics · Quantitative Biology 2023-03-22 Myriam Bontonou , Anaïs Haget , Maria Boulougouri , Jean-Michel Arbona , Benjamin Audit , Pierre Borgnat

The web contains countless semi-structured websites, which can be a rich source of information for populating knowledge bases. Existing methods for extracting relations from the DOM trees of semi-structured webpages can achieve high…

Artificial Intelligence · Computer Science 2018-04-13 Colin Lockard , Xin Luna Dong , Arash Einolghozati , Prashant Shiralkar

The ability to construct domain specific knowledge graphs (KG) and perform question-answering or hypothesis generation is a transformative capability. Despite their value, automated construction of knowledge graphs remains an expensive…

We describe a neural network model that jointly learns distributed representations of texts and knowledge base (KB) entities. Given a text in the KB, we train our proposed model to predict entities that are relevant to the text. Our model…

Computation and Language · Computer Science 2017-11-08 Ikuya Yamada , Hiroyuki Shindo , Hideaki Takeda , Yoshiyasu Takefuji

Renal Cell Carcinoma is typically asymptomatic at the early stages for many patients. This leads to a late diagnosis of the tumor, where the curability likelihood is lower, and makes the mortality rate of Renal Cell Carcinoma high, with…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Mohamad Mohamad , Francesco Ponzio , Santa Di Cataldo , Damien Ambrosetti , Xavier Descombes

Clinical trial records are variable resources or the analysis of patients and diseases. Information extraction from free text such as eligibility criteria and summary of results and conclusions in clinical trials would better support…

Computation and Language · Computer Science 2020-01-01 Yingcheng Sun , Kenneth Loparo