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The ability to reason beyond established knowledge allows Organic Chemists to solve synthetic problems and to invent novel transformations. Here, we propose a model which mimics chemical reasoning and formalises reaction prediction as…

Artificial Intelligence · Computer Science 2017-12-27 Marwin H. S. Segler , Mark P. Waller

Chemistry plays a key role in many aspects of astrophysical fluids. Atoms and molecules are agents for heating and cooling, determine the ionization fraction, serve as observational tracers, and build the molecular foundation of life. We…

The impossibility of experiencing the molecular world with our senses hampers teaching and understanding chemistry because very abstract concepts (such as atoms, chemical bonds, molecular structure, reactivity) are required for this…

Physics Education · Physics 2021-03-02 Thomas Weymuth , Markus Reiher

Both experimental and computational biology is becoming increasingly automated. Laboratory experiments are now performed automatically on high-throughput machinery, while computational models are synthesized or inferred automatically from…

Programming Languages · Computer Science 2018-05-08 Alessandro Abate , Luca Cardelli , Marta Kwiatkowska , Luca Laurenti , Boyan Yordanov

We discuss a method to describe the qualitative dynamics of chemical reaction networks in terms of symbolic dynamics. The method, that can be applied to mass-action reaction networks with separated timescales, uses solutions of the partial…

Molecular Networks · Quantitative Biology 2022-05-17 Aurélien Desoeuvres , Peter Szmolyan , Ovidiu Radulescu

For the investigation of chemical reaction networks, the efficient and accurate determination of all relevant intermediates and elementary reactions is mandatory. The complexity of such a network may grow rapidly, in particular if reactive…

Chemical Physics · Physics 2016-01-08 Maike Bergeler , Gregor N. Simm , Jonny Proppe , Markus Reiher

The development of chemical engineering technology is a multi-stage process that encompasses laboratory research, scaling up, and industrial deployment. This process demands interdisciplinary col laboration and typically incurs significant…

Chemical Physics · Physics 2025-09-10 Heng Zhang , Jibin Zhou , Feiyang Xu , Jian Cui , Yi Li , Fan Yang , Hao Wang , Xin Li , Mao Ye

The construction of a reaction network containing all relevant intermediates and elementary reactions is necessary for the accurate description of chemical processes. In the case of a complex chemical reaction (involving, for instance, many…

Chemical Physics · Physics 2017-12-19 Gregor N. Simm , Markus Reiher

AutoMeKin2021 is an updated version of tsscds2018, a program for the automated discovery of reaction mechanisms (J. Comput. Chem. 2018, 39, 1922-1930). This release features a number of new capabilities: rare-event molecular dynamics…

Computational techniques are required for narrowing down the vast space of possibilities to plausible prebiotic scenarios, since precise information on the molecular composition, the dominant reaction chemistry, and the conditions for that…

Molecular Networks · Quantitative Biology 2018-02-07 Jakob L. Andersen , Christoph Flamm , Daniel Merkle , Peter F. Stadler

We describe software and a language for quasibiological computations. Its theoretical basis is a unified theory of complex (adaptive) systems where all laws are regularities of relations between things or agents, and dynamics is made from…

Computational Physics · Physics 2007-05-23 Gerhard Mack , Jan Wuerthner

Motivation: SBML is the most widespread language for the definition of biochemical models. Although dozens of SBML simulators are available, there is a general lack of support to the integration of SBML models within open-standard…

Molecular Networks · Quantitative Biology 2021-06-07 Filippo Maggioli , Toni Mancini , Enrico Tronci

This paper introduces ChemGen, a software package that uses code generation to integrate multispecies thermodynamics and chemical kinetics into C+-based computational physics codes. ChemGen aims to make chemical kinetics more accessible in…

Computational Physics · Physics 2025-12-11 Ryan F. Johnson , Eric J. Ching , Ethan S. Genter , Joshua E. Lipman , Andrew D. Kercher , Jay Arcities , Hai Wang

CORSIKA 8 represents a significant update in the simulation of particle showers, building on the well-established foundation of CORSIKA 7. It has been entirely rewritten as a modular and modern C++ framework, addressing the limitations of…

High Energy Astrophysical Phenomena · Physics 2025-08-13 Marvin Gottowik

In this work, we present RePlaChem, a software library for reducing detailed large-scale plasma chemical mechanisms to smaller skeletal ones. The library parses a plasma chemical mechanism in the well-established format compatible with the…

Computational Physics · Physics 2025-07-08 Z. Nikolaou , E. Morais , S. Van Rompaey , C. Anastassiou , A. Bogaerts , V. Vavourakis

Chemists now routinely use software as part of their work. For example, virtual chemistry allows chemical reactions to be simulated. In particular, a selection of software is available for the visualisation of complex 3-dimensional…

Graphics · Computer Science 2013-07-25 Karl Harrison , Jonathan P. Bowen , Alice M. Bowen

Accurate simulation of dynamical processes in molecules and reactions is among the most challenging problems in quantum chemistry. Quantum computers promise efficient chemical simulation, but the existing quantum algorithms require many…

Artificial chemistry simulations produce many intriguing emergent behaviors, but they are often difficult to steer or control. This paper proposes a method for steering the dynamics of a classic artificial chemistry model, known as AlChemy…

Formal Languages and Automata Theory · Computer Science 2025-09-05 Devansh Vimal , Cole Mathis , Westley Weimer , Stephanie Forrest

The chemical reaction network (CRN) is a widely used formalism to describe macroscopic behavior of chemical systems. Available tools for CRN modelling and simulation require local access, installation, and often involve local file storage,…

Computational Engineering, Finance, and Science · Computer Science 2015-12-07 Peter Banda , Drew Blount , Christof Teuscher

We propose using semiconductor quantum dots for a simulation of chemical reactions as electrons are redistributed among such artificial atoms. We show that it is possible to achieve various reaction regimes and obtain different reaction…

Materials Science · Physics 2009-11-13 A. Yu. Smirnov , S. Savel'ev , L. G. Mourokh , Franco Nori