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Recent Covid-19 pandemic has demonstrated the need of efficient epidemic outbreak management. We study the optimal control problem of minimizing the fraction of infected population by applying vaccination and treatment control strategies,…

Social and Information Networks · Computer Science 2021-12-07 Jagtap Kalyani Devendra , Kundan Kandhway

In this paper we propose a data-driven model for the spread of SARS-CoV-2 and use it to design optimal control strategies of human-mobility restrictions that both curb the epidemic and minimize the economic costs associated with…

Optimization and Control · Mathematics 2021-05-21 Mikhail Hayhoe , Francisco Barreras , Victor M. Preciado

This work examines the use of reinforcement learning (RL) to optimize cyclic lockdowns, which is one of the methods available for control of the COVID-19 pandemic. The problem is structured as an optimal control system for tracking a…

Machine Learning · Computer Science 2020-09-11 Mauricio Arango , Lyudmil Pelov

The rapid spread of the Coronavirus (COVID-19) confronts policy makers with the problem of measuring the effectiveness of containment strategies, balancing public health considerations with the economic costs of social distancing measures.…

Physics and Society · Physics 2021-04-02 Claudius Gros , Roser Valenti , Lukas Schneider , Kilian Valenti , Daniel Gros

We propose a general Bayesian approach to modeling epidemics such as COVID-19. The approach grew out of specific analyses conducted during the pandemic, in particular an analysis concerning the effects of non-pharmaceutical interventions…

Applications · Statistics 2021-01-01 Samir Bhatt , Neil Ferguson , Seth Flaxman , Axel Gandy , Swapnil Mishra , James A. Scott

A simple analytical model for modeling the evolution of the 2020 COVID-19 pandemic is presented. The model is based on the numerical solution of the widely used Susceptible-Infectious-Removed (SIR) populations model for describing…

Populations and Evolution · Quantitative Biology 2020-08-26 Efthimios Kaxiras , George Neofotistos , Eleni Angelaki

The great challenge for the humanity of the year 2020 is the fight against COVID-19. The whole world is making a huge effort to find an effective vaccine with purpose to protect people not yet infected. The alternative solution remains…

Image and Video Processing · Electrical Eng. & Systems 2020-12-03 Mario Manzo , Simone Pellino

Governments across the world are currently facing the task of selecting suitable intervention strategies to cope with the effects of the COVID-19 pandemic. This is a highly challenging task, since harsh measures may result in economic…

Optimization and Control · Mathematics 2021-01-19 Andreas Kasis , Stelios Timotheou , Nima Monshizadeh , Marios Polycarpou

This paper develops an individual-based stochastic network SIR model for the empirical analysis of the Covid-19 pandemic. It derives moment conditions for the number of infected and active cases for single as well as multigroup epidemic…

Econometrics · Economics 2022-01-05 M. Hashem Pesaran , Cynthia Fan Yang

Most governments employ a set of quasi-standard measures to fight COVID-19 including wearing masks, social distancing, virus testing, contact tracing, and vaccination. However, combining these measures into an efficient holistic pandemic…

Theoretical Economics · Economics 2022-02-10 Balázs Pejó , Gergely Biczók

The COVID-19 pandemic led several countries to resort to social distancing, the only known way to slow down the spread of the virus and keep the health system under control. Here we use an individual based model (IBM) to study how the…

Populations and Evolution · Quantitative Biology 2020-08-18 Vitor M. Marquioni , Marcus A. M. de Aguiar

We develop methodology for a multistage decision problem with flexible number of stages in which the rewards are survival times that are subject to censoring. We present a novel Q-learning algorithm that is adjusted for censored data and…

Statistics Theory · Mathematics 2012-05-31 Yair Goldberg , Michael R. Kosorok

This paper presents a detailed mathematical investigation into the dynamics of COVID-19 infections through extended Susceptible-Infected-Recovered (SIR) and Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological models. By…

Populations and Evolution · Quantitative Biology 2025-05-21 Caleb Traxler , Minh Ton , Nameer Ahmed , Sasha Prostota , Annie Cheng

Various non pharmaceutical interventions have been settled to minimise the burden of the COVID-19 outbreak. We build a framework to analyse the dynamics of non pharmaceutical interventions, to distinguish between mitigations measures…

Populations and Evolution · Quantitative Biology 2023-01-23 Laurent Evain , Jean-Jacques Loeb

Due to the characteristics of COVID-19, the epidemic develops rapidly and overwhelms health service systems worldwide. Many patients suffer from systemic life-threatening problems and need to be carefully monitored in ICUs. Thus the…

Machine Learning · Computer Science 2020-07-20 Liantao Ma , Xinyu Ma , Junyi Gao , Chaohe Zhang , Zhihao Yu , Xianfeng Jiao , Wenjie Ruan , Yasha Wang , Wen Tang , Jiangtao Wang

We demonstrate an approach to replicate and forecast the spread of the SARS-CoV-2 (COVID-19) pandemic using the toolkit of probabilistic programming languages (PPLs). Our goal is to study the impact of various modeling assumptions and…

Machine Learning · Statistics 2022-03-08 Swapneel Mehta , Noah Kasmanoff

To reduce the impact of COVID-19 pandemic most countries have implemented several counter-measures to control the virus spread including school and border closing, shutting down public transport and workplace and restrictions on gathering.…

Social and Information Networks · Computer Science 2020-09-14 Ahmed Ben Said , Abdelkarim Erradi , Hussein Aly , Abdelmonem Mohamed

This study aims to determine an optimal control strategy for vaccine scheduling in COVID-19 pandemic treatment by converting widely acknowledged infectious disease model named SEIR into an optimal control problem. The problem is augmented…

Populations and Evolution · Quantitative Biology 2020-08-26 Syed Irfan Ali Meerza , Seyed M. Karimi , Bert B. Little , Jacek M. Zurada , Tamer Inanc

At the end of 2020, policy responses to the SARS-CoV-2 outbreak have been shaken by the emergence of virus variants. The emergence of these more contagious, more severe, or even vaccine-resistant strains have challenged worldwide policy…

Populations and Evolution · Quantitative Biology 2021-03-29 Aymeric Vie

The 2019 Novel Corona virus infection (COVID 19) is an ongoing public health emergency of international focus. Significant gaps persist in our knowledge of COVID 19 epidemiology, transmission dynamics, investigation tools and management,…

Physics and Society · Physics 2020-12-01 Anca Radulescu , Cassandra Williams , Kieran Cavanagh
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