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Related papers: Stretching DNA in hard-wall potential channels

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For an understanding of DNA elasticity at high mechanical loads (F > 30 pN), its helical nature needs to be taken into account, in the form of coupling between the twist and stretch degrees of freedom. The prevailing model for DNA…

Biological Physics · Physics 2016-06-29 Onno D. Broekmans , Graeme A. King , Greg J. Stephens , Gijs J. L. Wuite

A polymer chain confined in nano-scale geometry has been used to investigate the underlying mechanism of Nuclear Pore Complex (NPC), where transport of cargoes is directional. It was shown here that depending on the solvent quality (good or…

Soft Condensed Matter · Physics 2017-08-02 Sanjay Kumar , Sanjiv Kumar , Debaprasad Giri , Shesh Nath

In this work we propose a model for DNA double helix within the tight-binding framework that incorporates the helicity of the molecules. We have studied localization properties of three DNAsequences,the periodic poly(dG)-poly(dC) and…

Mesoscale and Nanoscale Physics · Physics 2015-07-27 Sourav Kundu , S. N. Karmakar

In this paper we study the shape characteristics of a polymer chain in a good solvent using a mesoscopic level of modelling. The dissipative particle dynamics simulations are performed in the $3D$ space at a range of chain lengths $N$. The…

Soft Condensed Matter · Physics 2016-11-24 Ostap Kalyuzhnyi , Jaroslav Ilnytskyi , Yurij Holovatch , Christian von Ferber

The binding of proteins onto DNA contributes to the shaping and packaging of genome as well as to the expression of specific genetic messages. With a view to understanding the interplay between the presence of proteins and the deformation…

Biological Physics · Physics 2014-05-30 Nicolas Clauvelin , Wilma K. Olson

The Peyrard-Bishop DNA model describes the molecular interactions with simple potentials which allow efficient calculations of melting temperatures. However, it is based on a Hamiltonian that does not consider the helical twist or any other…

Biomolecules · Quantitative Biology 2020-07-16 Mateus Rodrigues Leal , Gerald Weber

The mechanical properties of DNA are typically described by elastic theories with purely local couplings (on-site models). We discuss and analyze coarse-grained (oxDNA) and all-atom simulations, which indicate that in DNA distal sites are…

Soft Condensed Matter · Physics 2021-04-21 Enrico Skoruppa , Aderik Voorspoels , Jocelyne Vreede , Enrico Carlon

The inherent structure landscape for a system of hard spheres confined to a hard cylindrical channel, such that spheres can only contact their first and second neighbours, is studied using an analytical model that extends previous results…

Soft Condensed Matter · Physics 2021-12-15 Mahdi Zarif , Raymond J. Spiteri , Richard K. Bowles

The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally-constrained single molecules give the first direct measurement of this…

Soft Condensed Matter · Physics 2009-10-28 Randall D. Kamien , Tom C. Lubensky , Philip Nelson , Corey S. O'Hern

A couple of models are explained. Helicoidal PB model is studied in more details. It is shown that semi-discrete approximation yields to breather-type soliton moving along the chain. The model can explain local opening as a resonance mode.…

Soft Condensed Matter · Physics 2019-09-16 Slobodan Zdravkovic

Protein complexes involved in DNA mismatch repair appear to diffuse along dsDNA in order to locate a hemimethylated incision site via a dissociative mechanism. Here, we study the probability that these complexes locate a given target site…

Subcellular Processes · Quantitative Biology 2021-05-12 Kyle Crocker , James London , Andrés Medina , Richard Fishel , Ralf Bundschuh

Emitters strongly coupled to a photonic crystal provide a powerful platform for realizing novel quantum light-matter interactions. Here we study the optical properties of a three-level artificial atomic chain coupled to a one-dimensional…

Quantum Physics · Physics 2019-05-01 Guo-Zhu Song , Leong-Chuan Kwek , Fu-Guo Deng , Gui-Lu Long

The so called long range correlation properties of DNA sequences are studied using the variance analyses of the density distribution of a single or a group of nucleotides in a model independent way. This new method which was suggested…

Biological Physics · Physics 2007-05-23 A. K. Mohanty , A. V. S. S. Narayana Rao

We examine the elastic model of short circular DNA. We obtain analytic expressions for configurations, elastic energy, twist and linking number of our solutions. We find the onset of the plectonemic transition. We suggest ways to use our…

Soft Condensed Matter · Physics 2008-02-03 Boris Fain , Joseph Rudnick

We modify and extend the recently developed statistical mechanical model for predicting the thermodynamic properties of chain molecules having noncovalent double-stranded conformations, as in RNA or ssDNA, and $\beta-$sheets in protein, by…

Soft Condensed Matter · Physics 2009-11-07 Fei Liu , Luru Dai , Zhong-can Ou-Yang

The dynamics of individual DNA molecules in semidilute solutions undergoing planar extensional flow is simulated using a multi-particle Brownian dynamics algorithm, which incorporates hydrodynamic and excluded volume interactions in the…

Soft Condensed Matter · Physics 2020-07-03 Chandi Sasmal , Kai-Wen Hsiao , Charles M. Schroeder , J. Ravi Prakash

A simple one-dimensional lattice model is suggested to describe the experimentally observed plateau in force-stretching diagrams for some macromolecules. This chain model involves the nearest-neighbor interaction of a Morse-like potential…

Pattern Formation and Solitons · Physics 2015-06-03 P. L. Christiansen , A. V. Savin , A. V. Zolotaryuk

At the core of high throughput DNA sequencing platforms lies a bio-physical surface process that results in a random geometry of clusters of homogenous short DNA fragments typically hundreds of base pairs long - bridge amplification. The…

Genomics · Quantitative Biology 2015-08-13 Eliza O'Reilly , Francois Baccelli , Gustavo de Veciana , Haris Vikalo

DNA is a flexible molecule, but the degree of its flexibility is subject to debate. The commonly-accepted persistence length of $l_p \approx 500\,$\AA\ is inconsistent with recent studies on short-chain DNA that show much greater…

Time and spatial damping of transverse magnetohydrodynamic (MHD) kink oscillations is a source of information on the cross-field variation of the plasma density in coronal waveguides. We show that a probabilistic approach to the problem of…

Solar and Stellar Astrophysics · Physics 2014-05-14 I. Arregui , A. Asensio Ramos