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Related papers: Stretching DNA in hard-wall potential channels

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Minuscule molecular forces can transform DNA into a structure that is elongated by more than half its original length. We demonstrate that this pronounced conformational transition is of relevance to ongoing experimental and theoretical…

Materials Science · Physics 2010-07-06 Paul Maragakis , Ryan Lee Barnett , Efthimios Kaxiras , Marcus Elstner , Thomas Frauenheim

Single molecule experiments on B-DNA stretching have revealed one or two structural transitions, when increasing the external force. They are characterized by a sudden increase of DNA contour length and a decrease of the bending rigidity.…

Soft Condensed Matter · Physics 2012-10-25 Manoel Manghi , Nicolas Destainville , John Palmeri

We develop an analytical method for studying the properties of a non-interacting Wormlike Chain (WLC) in confined geometries. The mean field-like theory replaces the rigid constraints of confinement with average constraints, thus allowing…

Soft Condensed Matter · Physics 2009-11-13 Greg Morrison , D. Thirumalai

We study some mesoscopic properties of electron transport by employing one-dimensional chains and Anderson tight-binding model. Principal attention is paid to the resistance of finite-length chains with disordered white-noise potential. We…

Mesoscale and Nanoscale Physics · Physics 2015-06-24 V. Dossetti-Romero , F. M. Izrailev , A. A. Krokhin

While analyzing the persistence length of DNA atomistic simulations Wu et al. [J. Chem. Phys. 142, 125103 (2015)] introduced an empirical formula to account for the observed length-dependence. In particular they found that the persistence…

Soft Condensed Matter · Physics 2021-10-26 Midas Segers , Enrico Skoruppa , Jan A. Stevens , Merijn Vangilbergen , Aderik Voorspoels , Enrico Carlon

Previous numerical investigations of an one-dimensional DNA model with an extended modified coupling constant by transcripting enzyme are integrated to longer time and demonstrated explicitly the trapping of breathers by DNA chains with…

solv-int · Physics 2021-01-21 Julian Juhi-Lian Ting

We develop a continuum elastic approach to examining the bending mechanics of semiflexible filaments with a local internal degree of freedom that couples to the bending modulus. We apply this model to study the nonlinear mechanics of a…

Soft Condensed Matter · Physics 2013-02-12 Arthur A. Evans , Alex J. Levine

The chiral nature of DNA plays a crucial role in cellular processes. Here we use magnetic tweezers to explore one of the signatures of this chirality, the coupling between stretch and twist deformations. We show that the extension of a…

Biomolecules · Quantitative Biology 2009-09-29 Timothee Lionnet , Sylvain Joubaud , Richard Lavery , David Bensimon , Vincent Croquette

Double-stranded DNA `overstretches' at a pulling force of about 65 pN, increasing in length by a factor of 1.7. The nature of the overstretched state is unknown, despite its considerable importance for DNA's biological function and…

Statistical Mechanics · Physics 2009-11-13 Stephen Whitelam , Sander Pronk , Phillip L. Geissler

Advanced Monte Carlo simulations are used to study the effect of nano-slit confinement on metric and topological properties of model DNA chains. We consider both linear and circularised chains with contour lengths in the 1.2--4.8 $\mu$m…

Biological Physics · Physics 2012-04-11 C. Micheletti , E. Orlandini

The characterization of the long-range order and fractal properties of DNA sequences has proved a difficult though highly rewarding task due mainly to the mosaic character of DNA consisting of many interwoven patches of various lengths with…

Statistical Mechanics · Physics 2009-11-07 Alexandre Rosas , Edvaldo Nogueira , José F. Fontanari

We report model calculations on DNA single strands which describe the equilibrium dynamics and kinetics of hairpin formation and melting. Modeling is at the level of single bases. Strand rigidity is described in terms of simple polymer…

Soft Condensed Matter · Physics 2007-10-01 Jalal Errami , Michel Peyrard , Nikos Theodorakopoulos

A statistical method is developed to estimate the maximum amplitude of the base pair fluctuations in a three dimensional mesoscopic model for nucleic acids. The base pair thermal vibrations around the helix diameter are viewed as a Brownian…

Soft Condensed Matter · Physics 2021-05-20 Marco Zoli

The strength of the spin-orbit interaction relevant to transport in a low dimensional structure depends critically on the relative geometrical arrangement of current carrying orbitals. Recent tight-binding orbital models for spin transport…

Mesoscale and Nanoscale Physics · Physics 2017-10-20 Solmar Varela , Vladimiro Mujica , Ernesto Medina

We use a bath of chaotic surface waves in water to mechanically and macroscopically mimic the thermal behavior of a short articulated chain with only nearest-neighbor interactions. The chaotic waves provide isotropic and random agitation to…

Soft Condensed Matter · Physics 2015-03-05 Kyle J. Welch , Clayton S. G. Kilmer , Eric I. Corwin

The double-helical structure of DNA results from canonical base pairing and stacking interactions. However, variations from steady-state conformations result from mechanical perturbations in cells. These different topologies have…

Biomolecules · Quantitative Biology 2019-04-05 Jack W Shepherd , Robert J Greenall , Matt I J Probert , Agnes Noy , Mark C Leake

A unified model is constructed to study the recently observed DNA entropic elasticity, cooperative extensibility, and supercoiling property. With the introduction of a new structural parameter (the folding angle $\phi$), bending…

Soft Condensed Matter · Physics 2007-05-23 Zhou Haijun , Zhang Yang , Ou-Yang Zhong-can

Localization property in the disordered few-chain DNA systems with a long-range correlation is numerically investigated. We apply the chain system with the correlated disorder in the interchain and/or intrachain hoppings to the simple model…

Disordered Systems and Neural Networks · Physics 2009-09-29 Hiroaki Yamada

Flexibility of short DNA helices is important for the biological functions such as nucleosome formation and DNA-protein recognition. Recent experiments suggest that short DNAs of tens of base pairs (bps) may have apparently higher…

Biological Physics · Physics 2015-06-24 Yuan-Yan Wu , Lei Bao , Xi Zhang , Zhi-Jie Tan

We present a simple model which describes elastic response of single-stranded DNA (ssDNA) to stretching, including the regime of very high force (up to 1000 pN). ssDNA is modelled as a discreet persistent chain, whose ground state is a…

Biomolecules · Quantitative Biology 2009-11-13 Alexei V. Tkachenko
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