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Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and the fourth most common cause of cancer-related death worldwide. Understanding the underlying gene mutations in HCC provides great prognostic value for…

The objective of this paper is to provide a baseline for performing multi-modal data classification on a novel open multimodal dataset of hepatocellular carcinoma (HCC), which includes both image data (contrast-enhanced CT and MRI images)…

Predicting the subcellular localization of proteins is an important and challenging problem. Traditional experimental approaches are often expensive and time-consuming. Consequently, a growing number of research efforts employ a series of…

Machine Learning · Computer Science 2017-04-19 Shixiang Wan , Quan Zou

Multi-instance multi-label (MIML) learning is a challenging problem in many aspects. Such learning approaches might be useful for many medical diagnosis applications including breast cancer detection and classification. In this study subset…

Computer Vision and Pattern Recognition · Computer Science 2015-10-13 Baris Gecer , Ozge Yalcinkaya , Onur Tasar , Selim Aksoy

Predicting genetic mutations from whole slide images is indispensable for cancer diagnosis. However, existing work training multiple binary classification models faces two challenges: (a) Training multiple binary classifiers is inefficient…

Computer Vision and Pattern Recognition · Computer Science 2024-06-06 Gexin Huang , Chenfei Wu , Mingjie Li , Xiaojun Chang , Ling Chen , Ying Sun , Shen Zhao , Xiaodan Liang , Liang Lin

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is a leading cause of cancer-related death worldwide. However, cure is not possible with currently used therapies, and there is not so much approved targeted…

Genomics · Quantitative Biology 2017-07-18 Liang Yu , Fengdan Xu , Lin Gao

Hierarchical multi-label text classification (HMTC) aims at utilizing a label hierarchy in multi-label classification. Recent approaches to HMTC deal with the problem of imposing an over-constrained premise on the output space by using…

Computation and Language · Computer Science 2024-06-21 Simon Yu , Jie He , Víctor Gutiérrez-Basulto , Jeff Z. Pan

Unlike the typical classification setting where each instance is associated with a single class, in multi-label learning each instance is associated with multiple classes simultaneously. Therefore the learning task in this setting is to…

Machine Learning · Computer Science 2022-11-30 Harris Papadopoulos

In multi-label classification, an instance may be associated with a set of labels simultaneously. Recently, the research on multi-label classification has largely shifted its focus to the other end of the spectrum where the number of labels…

Machine Learning · Computer Science 2016-04-06 Li Li , Houfeng Wang

Multi-label classification (MLC) is a supervised learning problem in which, contrary to standard multiclass classification, an instance can be associated with several class labels simultaneously. In this chapter, we advocate a rule-based…

Machine Learning · Computer Science 2020-12-09 Eneldo Loza Mencía , Johannes Fürnkranz , Eyke Hüllermeier , Michael Rapp

This work proposes a pipeline to predict treatment response to intra-arterial therapy of patients with Hepatocellular Carcinoma (HCC) for improved therapeutic decision-making. Our graph neural network model seamlessly combines heterogeneous…

Image and Video Processing · Electrical Eng. & Systems 2019-12-03 Junlin Yang , Nicha C. Dvornek , Fan Zhang , Julius Chapiro , MingDe Lin , Aaron Abajian , James S. Duncan

Even with the luxury of having abundant data, multi-label classification is widely known to be a challenging task to address. This work targets the problem of multi-label meta-learning, where a model learns to predict multiple labels within…

Computer Vision and Pattern Recognition · Computer Science 2021-10-27 Christian Simon , Piotr Koniusz , Mehrtash Harandi

Hepatocellular carcinoma (HCC) is a common type of liver cancer whose early-stage diagnosis is a common challenge, mainly due to the manual assessment of hematoxylin and eosin-stained whole slide images, which is a time-consuming process…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Ajinkya Deshpande , Deep Gupta , Ankit Bhurane , Nisha Meshram , Sneha Singh , Petia Radeva

Histology images with multi-gigapixel of resolution yield rich information for cancer diagnosis and prognosis. Most of the time, only slide-level label is available because pixel-wise annotation is labour intensive task. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2022-09-08 Made Satria Wibawa , Kwok-Wai Lo , Lawrence Young , Nasir Rajpoot

One primary goal of precision medicine is to estimate the individualized treatment rules (ITRs) that optimize patients' health outcomes based on individual characteristics. Health studies with multiple treatments are commonly seen in…

Methodology · Statistics 2025-05-07 Xuqiao Li , Qiuyan Zhou , Ying Wu , Ying Yan

Hierarchical multi-label classification (HMC) is a challenging classification task extending standard multi-label classification problems by imposing a hierarchy constraint on the classes. In this paper, we propose C-HMCNN(h), a novel…

Machine Learning · Computer Science 2021-11-29 Eleonora Giunchiglia , Thomas Lukasiewicz

In this paper a high speed neural network classifier based on extreme learning machines for multi-label classification problem is proposed and dis-cussed. Multi-label classification is a superset of traditional binary and multi-class…

Machine Learning · Computer Science 2016-09-06 Meng Joo Er , Rajasekar Venkatesan , Ning Wang

Genetic studies have identified associations between gene mutations and clear cell renal cell carcinoma (ccRCC). Because the complete gene mutational landscape cannot be characterized through biopsy and sequencing assays for each patient,…

In real-world applications, as data availability increases, obtaining labeled data for machine learning (ML) projects remains challenging due to the high costs and intensive efforts required for data annotation. Many ML projects,…

Machine Learning · Computer Science 2024-12-24 Ismail Hakki Karaman , Gulser Koksal , Levent Eriskin , Salih Salihoglu

This study aimed to develop a classifier of prognosis after resection or liver transplantation (LT) for HCC by directly analysing the ubiquitously available histological images using deep learning based neural networks. Nucleus map set was…

Computer Vision and Pattern Recognition · Computer Science 2021-06-02 Zhikun Liu , Yuanpeng Liu , Yuan Hong , Jinwen Meng , Jianguo Wang , Shusen Zheng , Xiao Xu
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