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Machine learning-based multi-label medical text classifications can be used to enhance the understanding of the human body and aid the need for patient care. We present a broad study on clinical natural language processing techniques to…

Information Retrieval · Computer Science 2020-04-02 Vithya Yogarajan , Jacob Montiel , Tony Smith , Bernhard Pfahringer

Cell detection in histopathology images is of great interest to clinical practice and research, and convolutional neural networks (CNNs) have achieved remarkable cell detection results. Typically, to train CNN-based cell detection models,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-17 Zipei Zhao , Fengqian Pang , Yaou Liu , Zhiwen Liu , Chuyang Ye

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. Several diagnostic methods, such as imaging modalities and Serum Alpha-Fetoprotein (AFP) testing, have been used for HCC detection; however,…

Genomics · Quantitative Biology 2025-07-02 Aram Ansary Ogholbake , Qiang Cheng

Image classification is one of the most important areas in computer vision. Hierarchical multi-label classification applies when a multi-class image classification problem is arranged into smaller ones based upon a hierarchy or taxonomy.…

Computer Vision and Pattern Recognition · Computer Science 2022-09-14 Khondaker Tasrif Noor , Antonio Robles-Kelly , Brano Kusy

A comprehensive and reliable survival prediction model is of great importance to assist in the personalized management of Head and Neck Cancer (HNC) patients treated with curative Radiation Therapy (RT). In this work, we propose IMLSP, an…

Computer Vision and Pattern Recognition · Computer Science 2024-05-10 Meixu Chen , Kai Wang , Jing Wang

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Akihiko Yoshizawa , Tetsuo Ushiku , Masashi Fukayama , Masanobu Kitagawa , Masaru Kitsuregawa , Tatsuya Harada

Multiple Instance learning (MIL) models have been extensively used in pathology to predict biomarkers and risk-stratify patients from gigapixel-sized images. Machine learning problems in medical imaging often deal with rare diseases, making…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Dinkar Juyal , Siddhant Shingi , Syed Ashar Javed , Harshith Padigela , Chintan Shah , Anand Sampat , Archit Khosla , John Abel , Amaro Taylor-Weiner

Single-cell datasets often lack individual cell labels, making it challenging to identify cells associated with disease. To address this, we introduce Mixture Modeling for Multiple Instance Learning (MMIL), an expectation maximization…

Quantitative Methods · Quantitative Biology 2024-06-13 Erin Craig , Timothy Keyes , Jolanda Sarno , Maxim Zaslavsky , Garry Nolan , Kara Davis , Trevor Hastie , Robert Tibshirani

Multi-label classification (MC) is a standard machine learning problem in which a data point can be associated with a set of classes. A more challenging scenario is given by hierarchical multi-label classification (HMC) problems, in which…

Machine Learning · Computer Science 2022-10-05 Eleonora Giunchiglia , Thomas Lukasiewicz

Computational pathology models that use digitized histopathology whole-slide images have the potential to become a cost-effective and scalable alternative to molecular assays for the prediction of genomic biomarkers, a key task in precision…

Quantitative Methods · Quantitative Biology 2026-03-03 Ekaterina Redekop , Eric Zimmermann , Ava P Amini , Alex X Lu , Neil Tenenholtz , James Brian Hall , Lorin Crawford , Kristen A Severson

Longitudinal MRI analysis is crucial for predicting disease outcomes, particularly in chronic conditions like hepatocellular carcinoma (HCC), where early detection can significantly influence treatment strategies and patient prognosis. Yet,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-23 Jakob Nolte , Maureen M. J. Guichelaar , Donald E. Bouman , Stephanie M. van den Berg , Maryam Amir Haeri

With the emergence of diverse data collection techniques, objects in real applications can be represented as multi-modal features. What's more, objects may have multiple semantic meanings. Multi-modal and Multi-label (MMML) problem becomes…

Machine Learning · Computer Science 2019-07-30 Yi Zhang , Cheng Zeng , Hao Cheng , Chongjun Wang , Lei Zhang

Cell detection in histopathology images is of great value in clinical practice. \textit{Convolutional neural networks} (CNNs) have been applied to cell detection to improve the detection accuracy, where cell annotations are required for…

Computer Vision and Pattern Recognition · Computer Science 2021-07-01 Zipei Zhao , Fengqian Pang , Zhiwen Liu , Chuyang Ye

The problem of multilabel classification when the labels are related through a hierarchical categorization scheme occurs in many application domains such as computational biology. For example, this problem arises naturally when trying to…

Machine Learning · Computer Science 2012-05-14 Sara Mostafavi , Quaid Morris

Class-imbalance is an inherent characteristic of multi-label data which affects the prediction accuracy of most multi-label learning methods. One efficient strategy to deal with this problem is to employ resampling techniques before…

Machine Learning · Computer Science 2021-05-18 Bin Liu , Grigorios Tsoumakas

Multi-label classification is an important learning problem with many applications. In this work, we propose a principled similarity-based approach for multi-label learning called SML. We also introduce a similarity-based approach for…

Machine Learning · Statistics 2017-10-31 Ryan A. Rossi , Nesreen K. Ahmed , Hoda Eldardiry , Rong Zhou

Data collection from manual labeling provides domain-specific and task-aligned supervision for data-driven approaches, and a critical mass of well-annotated resources is required to achieve reasonable performance in natural language…

Computation and Language · Computer Science 2023-11-09 Zhengyuan Liu , Hai Leong Chieu , Nancy F. Chen

Multi-label image classification presents a challenging task in many domains, including computer vision and medical imaging. Recent advancements have introduced graph-based and transformer-based methods to improve performance and capture…

Computer Vision and Pattern Recognition · Computer Science 2024-04-15 Ahmad Sajedi , Samir Khaki , Yuri A. Lawryshyn , Konstantinos N. Plataniotis

Multimodal learning that integrates histopathology images and genomic data holds great promise for cancer survival prediction. However, existing methods face key limitations: 1) They rely on multimodal mapping and metrics in Euclidean…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Jiaqi Yang , Wenting Chen , Xiaohan Xing , Sean He , Xiaoling Luo , Xinheng Lyu , Linlin Shen , Guoping Qiu

The learning from imbalanced data is a deeply studied problem in standard classification and, in recent times, also in multilabel classification. A handful of multilabel resampling methods have been proposed in late years, aiming to balance…

Machine Learning · Computer Science 2018-02-15 Francisco Charte , Antonio J. Rivera , María J. del Jesus , Francisco Herrera