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Two full rotating gantry with different nozzles (Multipurpose nozzle with MLC, Scanning Dedicated nozzle) with conventional cyclotron system is installed and under commissioning for various proton treatment options at Samsung Medical Center…

Stereotactic body radiation therapy allows for a precise and accurate dose delivery. Organ motion during treatment bears the risk of undetected high dose healthy tissue exposure. An organ very susceptible to high dose is the oesophagus. Its…

Medical Physics · Physics 2021-06-22 Tobias Fechter , Sonja Adebahr , Anca-Ligia Grosu , Dimos Baltas

Purpose: To evaluate reliability of upright CT for proton dose calculation and feasibility of a simplified phantom configuration for accelerated routine QA. Methods: A calibration phantom was scanned on an upright CT following consensus…

Radiation dose is an important performance indicator of a dedicated breast CT (DBCT). In this paper, the method of putting thermoluminescent dosimeters (TLD) into a breast shaped PMMA phantom to study the dose distribution in breasts was…

Medical Physics · Physics 2013-05-14 Shen Shan-Wei , Wang Yan-Fang , Shu Hang , Tang Xiao , Wei Cun-Feng , Song Yu-Shou , Shi Rong-Jian , Wei Long

Computed Tomography (CT) imaging is one of the most influential diagnostic methods. In clinical reconstruction, an effective energy is used instead of total X-ray spectrum. This approximation causes an accuracy decline. To increase the…

Emerging Technologies · Computer Science 2018-07-25 Neda Gholami , Mohammad Mahdi Dehshibi , Mahmood Fazlali , Antonio Rueda-Toicen , Hector Zenil , Andrew Adamatzky

Recently, Yamashita et al. reported direct measurements of ionizing radiation doses to individual organs in postmortem (using OSL dosimetry) that were exposed in the most frequent clinical CT scan protocols, corresponding to the whole body,…

The percentage depth dose distributions in inhomogeneous phantoms with lung and bone equivalent media are studied. For lung equivalent media a Balsa wood is used, and for a soft bone equivalent media a compound material with epoxy resin,…

Dosimetry audits are carried out to determine how well radiotherapy is delivered to the patient. It is also used to understand the uncertainty introduced into the measurement result when using different computational models. As measurement…

Prostate cancer is one of the most common types of cancer in men. Its diagnosis by biopsy requires a high level of expertise and precision from the surgeon, so the results are highly operator-dependent. The aim of this work is to develop a…

Femoral artery access is essential for numerous clinical procedures, including diagnostic angiography, therapeutic catheterization, and emergency interventions. Despite its critical role, successful vascular access remains challenging due…

Robotics · Computer Science 2025-08-15 Lidia Al-Zogbi , Deepak Raina , Vinciya Pandian , Thorsten Fleiter , Axel Krieger

Purpose: This work describes the development and pilot implementation of a comprehensive remote dosimetry audit for Ir-192 high-dose-rate interstitial brachytherapy, integrating independent experimental and computational dosimetry within a…

The highly energetic electrons in a transmission electron microscope (TEM) can alter or even completely destroy the structure of samples before sufficient information can be obtained. This is especially problematic in the case of zeolites,…

Materials Science · Physics 2021-05-05 Abner Velazco , Daen Jannis , Armand Béché , Johan Verbeeck

Purpose: Variations in proton Relative Biological Effectiveness (RBE) with Linear Energy Transfer (LET) remain one of the largest sources of uncertainty in proton radiotherapy. This work seeks to identify physics-based metrics which can be…

Medical Physics · Physics 2018-12-05 Stephen J McMahon , Harald Paganetti , Kevin M Prise

The high precision and conformity of intensity-modulated particle therapy (IMPT) comes at the cost of susceptibility to treatment uncertainties in particle range and patient set-up. Dose uncertainty quantification and mitigation, which is…

Medical Physics · Physics 2021-11-17 Pia Stammer , Lucas Burigo , Oliver Jäkel , Martin Frank , Niklas Wahl

Radiotherapy is sensitive to executional and preparational uncertainties that propagate to uncertainty in dose and plan quality indicators like dose-volume histograms (DVHs). Current approaches to quantify and mitigate such uncertainties…

Medical Physics · Physics 2020-10-27 Niklas Wahl , Philipp Hennig , Hans-Peter Wieser , Mark Bangert

Purpose: To validate the accuracy of 4D Monte Carlo (4DMC) simulations to calculate dose deliveries to a deforming anatomy in the presence of realistic respiratory motion traces. A previously developed deformable lung phantom comprising an…

Medical Physics · Physics 2023-05-04 Sara Gholampourkashi , Joanna E. Cygler , Bernie Lavigne , Emily Heath

The authors propose robust adaptive strategies based on stochastic minimax optimization for a series of simulated treatments on a one-dimensional patient phantom. The plan applied during the first fractions should be able to handle…

Optimization and Control · Mathematics 2018-10-01 Michelle Böck , Anders Forsgren , Kjell Eriksson , Björn Hårdemark

To accurately verify the dose of intensity-modulated radiation therapy (IMRT), we have used a global optimization method to investigate a new dose-verification algorithm. In practical application of this quality assurance (QA) procedure,…

Medical Physics · Physics 2007-05-23 Dong Hyun Park , Sung-Yong Park , Dahl Park , Tae-Hyun Kim , Kyung Hwan Shin , Dae Yong Kim , Kwan-Ho Cho

Purpose: The purpose of the work was experimental investigations of the breast dose distributions with adaptive filtration. Adaptive filtration reduces detector dynamic range and improves image quality. The adaptive filter with…

Medical Physics · Physics 2017-02-15 Polad M. Shikhaliev

A standard dose of radioactive tracer must be delivered into the patients body to obtain high-quality Positron Emission Tomography (PET) images for diagnostic purposes, which raises the risk of radiation harm. A reduced tracer dose, on the…