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We present a method of optical magnetometry with parts-per-billion resolution that is able to detect biomagnetic signals generated from the human brain and heart in Earth's ambient environment. Our magnetically silent sensors measure the…
The design of a loop-gap-resonator RF coil optimized for ex vivo mouse brain microscopy at ultra high fields is described and its properties characterized using simulations, phantoms and experimental scans of mouse brains fixed in 10%…
Magnetic Resonance Imaging (MRI) is universally acknowledged as an excellent tool to extract detailed spatial information with minimally invasive measurements. Efforts toward ultra-low-field (ULF) MRI are made to simplify the scanners and…
We develop a novel next generation light-weight highly flexible pediatric coil array, combine it with a high-density pediatric posterior array or conventional posterior phased array, and determine feasibility of pediatric clinical use. A…
High-resolution whole-brain in vivo MR imaging at mesoscale resolutions remains challenging due to long scan durations, motion artifacts, and limited signal-to-noise ratio (SNR). This study proposes Rotating-view super-resolution…
The brain deformation that occurs during neurosurgery is a serious issue impacting the patient "safety" as well as the invasiveness of the brain surgery. Model-driven compensation is a realistic and efficient solution to solve this problem.…
Access to Magnetic Resonance Imaging system assembly knowledge can be expanded by leveraging open-source hardware and software, simplified installation requirements, and collaborative training initiatives. To this end, we conducted a…
Brain atrophy and white matter hyperintensity (WMH) are critical neuroimaging features for ascertaining brain injury in cerebrovascular disease and multiple sclerosis. Automated segmentation and quantification is desirable but existing…
Magnetic resonance imaging (MRI) is the standard modality to understand human brain structure and function in vivo (antemortem). Decades of research in human neuroimaging has led to the widespread development of methods and tools to provide…
Obtaining high quality images of the spinal cord with MRI is difficult, partly due to the fact that the spinal cord is surrounded by a number of structures that have differing magnetic susceptibility. This causes inhomogeneities in the…
Halbach magnets are a source of homogeneous magnetic field in an enclosed volume while keeping stray fields at a minimum. Here, we present the design, construction, and characterization for a 10 cm inner diameter double Halbach ring…
Magnetic resonance spectroscopic imaging (MRSI) enables the simultaneous non-invasive acquisition of MR spectra from multiple spatial locations inside the brain. While 1H-MRSI is increasingly used in the human brain, it is not yet widely…
Magnetic Resonance Imaging (MRI) is essential for noninvasive generation of high-quality images of human tissues. Accurate segmentation of MRI data is critical for medical applications like brain anatomy analysis and disease detection.…
Magnetic resonance imaging (MRI) has revolutionized biomedical science by providing non-invasive, three-dimensional biological imaging. However, spatial resolution in conventional MRI systems is limited to tens of microns, which is…
Purpose: MRI gradients with a conventional, bipolar design generally face a trade-off between performance, encoding ambiguity, and circumventing the latter by means of RF selectivity. This problem is particularly limiting in cutting-edge…
The human brain is a complex system requiring both macroscopic and microscopic components for comprehensive understanding. However, mapping nonlinear relationships between these scales remains challenging due to technical limitations and…
Purpose: Diffusion MRI has shown promise for breast cancer screening, lesion characterization,and treatment response monitoring without contrast agents, but further translation is constraint by the gradient performance of conventional…
It is well known that magnetic resonance imaging (MRI) at 7 Tesla (7T) and higher magnets can provide much better signal sensitivity compared with lower field strengths. However, variety of commercially available ultra-high-field MRI coils…
Three-dimensional reconstruction of cortical surfaces from MRI for morphometric analysis is fundamental for understanding brain structure. While high-field MRI (HF-MRI) is standard in research and clinical settings, its limited availability…
Purpose: Conventional MRI is relying on the assumption of the magnetic field being homogeneous in direction and amplitude. However, with the growing interest in portable, affordable point-of-care MRI systems, these assumptions do not…