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Variations of transport efficiency in structured environments between distinct individuals in actively self-propelled systems is both hard to study and poorly understood. Here, we study the transport of a non-tumbling {\ecoli} strain, an…

Soft Condensed Matter · Physics 2023-08-28 Pooja Chopra , David Quint , Ajay Gopinathan , Bin Liu

Host-to-host variability with respect to interactions between microorganisms and multicellular hosts are commonly observed in infection and in homeostasis. However, the majority of mechanistic models used in analyzing host-microorganism…

Populations and Evolution · Quantitative Biology 2015-06-19 Sayak Mukherjee , Kristin E. Weimer , Sang-Cheol Seok , Will C. Ray , C. Jayaprakash , Veronica J. Vieland , W. Edward Swords , Jayajit Das

Adhesive cell-substrate interactions are crucial for cell motility and are responsible for the necessary traction that propels cells. These interactions can also change the shape of the cell, analogous to liquid droplet wetting on adhesive…

Biological cells are able to adapt their behaviour in response to environmental cues. Durotaxis is a phenomenon in which cells adjust their migration depending on the mechanical properties of a surrounding substrate. Although durotaxis has…

Biological Physics · Physics 2026-05-11 Sohei Nakamura , Mitsusuke Tarama

We study methylation dynamics of the chemoreceptors as an {\sl E.coli} cell moves around in a spatially varying chemo-attractant environment. We consider attractant concentration with strong and weak spatial gradient. During the uphill and…

Cell Behavior · Quantitative Biology 2022-01-28 Shobhan Dev Mandal , Sakuntala Chatterjee

Thanks to recent technological advances, it is now possible to track with an unprecedented precision and for long periods of time the movement patterns of many living organisms in their habitat. The increasing amount of data available on…

Populations and Evolution · Quantitative Biology 2015-05-19 Denis Boyer , Peter D. Walsh

Navigation of microorganisms is controlled by internal processes ultimately sensitive to mechanical or chemical signaling encountered along the path. In many natural environments, such as porous soils or physiological ducts, motile species…

Lately, experimental research on microbial symbioses based on nutrient exchange and interdependence has yielded a number of interesting findings, however an in-depth mathematical description of the exact underlying dynamics of such…

Populations and Evolution · Quantitative Biology 2019-08-08 Matthias M. Fischer

Swimming cells and microorganisms must often move though complex fluids that contain an immersed microstructure such as polymer molecules, or filaments. In many important biological processes, such as mammalian reproduction and bacterial…

Fluid Dynamics · Physics 2018-08-06 Arshad Kamal , Eric E Keaveny

Bacteria can spontaneously develop collective motions by aligning their motions in dense systems. Here, we show that bacteria can also respond collectively to an alternating electrical field and form dynamic clusters oscillating at the same…

Soft Condensed Matter · Physics 2022-10-11 Mei Mei Bao , Isaiah Eze Igwe , Kang Chen , Tian Hui Zhang

Related groups of microbes are widely distributed across Earth's habitats, implying numerous dispersal and adaptation events over evolutionary time. However, to date, relatively little is known about the characteristics and mechanisms of…

Populations and Evolution · Quantitative Biology 2023-02-02 Alexander L. Jaffe , Cindy J. Castelle , Jillian F. Banfield

Bacteria can adjust their swimming behaviour in response to chemical variations, a phenomenon known as chemotaxis. This process is characterised by a drift velocity that depends non-linearly on the concentration of chemical species and its…

Fluid Dynamics · Physics 2026-05-07 Adam Gargasson , Julien Bouvard , Carine Douarche , Peter Mergaert , Harold Auradou

Recent studies have shown that packings of cells, both eukaryotic cellular tissues and growing or swarming bacterial colonies, can often be understood as active nematic fluids. A key property of volume-conserving active nematic model…

Soft Condensed Matter · Physics 2022-05-12 Fabian Jan Schwarzendahl , Daniel A. Beller

A number of biological processes, such as embryo development, cancer metastasis or wound healing, rely on cells moving in concert. The mechanisms leading to the emergence of coordinated motion remain however largely unexplored. Although…

Cell Behavior · Quantitative Biology 2011-08-23 Alexandre J Kabla

Many biological populations, such as bacterial colonies, have developed through evolution a protection mechanism, called bet-hedging, to increase their probability of survival under stressful environmental fluctutation. In this context, the…

Populations and Evolution · Quantitative Biology 2017-05-24 Masaki Ogura , Masashi Wakaiki , Harvey Rubin , Victor M. Preciado

Directed cell motion in response to an external chemical gradient occurs in many biological phenomena such as wound healing, angiogenesis, and cancer metastasis. Chemotaxis is often characterized by the accuracy, persistence, and speed of…

Cell Behavior · Quantitative Biology 2019-06-19 Julien Varennes , Hye-ran Moon , Soutick Saha , Andrew Mugler , Bumsoo Han

Communication between cells is realized by exchange of biochemical substances. Due to internal organization of living systems and variability of external parameters, the exchange is heavily influenced by perturbations of various parameters…

Chaotic Dynamics · Physics 2015-05-19 Dragutin T. Mihailovic , Igor Balaz

Organisms that grow and survive in uncertain environments may need to change their physiological state as the environment changes. When the environment is uncertain, one strategy known as bet-hedging is to make these changes randomly and…

Cell Behavior · Quantitative Biology 2023-04-28 David Lacoste , Olivier Rivoire , David S. Tourigny

In the chemotactic motion of Escherichia coli, the switching of transmembrane chemoreceptors between active and inactive states is one of the most important steps of the signaling pathway. We study the effect of this switching time-scale on…

Cell Behavior · Quantitative Biology 2022-08-18 Shobhan Dev Mandal , Sakuntala Chatterjee

The dispersal of cells from an initially constrained location is a crucial aspect of many physiological phenomena ranging from morphogenesis to tumour spreading. In such processes, the way cell-cell interactions impact the motion of single…