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Bacteria are often exposed to multiple stimuli in complex environments, and their efficient chemotactic decisions are critical to survive and grow in their native environments. Bacterial responses to the environmental stimuli depend on the…

Quantitative Methods · Quantitative Biology 2021-06-10 Jeungeun Park , Zahra Aminzare

We study analytically and numerically a model metabolic cycle composed of an arbitrary number of species of catalytically active particles. Each species converts a substrate into a product, the latter being used as the substrate by the next…

Soft Condensed Matter · Physics 2023-09-29 Vincent Ouazan-Reboul , Jaime Agudo-Canalejo , Ramin Golestanian

The large scale behaviour of a population of cells that grow and interact through the concentration field of the chemicals they secrete is studied using dynamical renormalization group methods. The combination of the effective long-range…

Cell Behavior · Quantitative Biology 2015-01-19 Anatolij Gelimson , Ramin Golestanian

Bacterial chemotaxis in Escherichia coli is a canonical system for the study of signal transduction. A remarkable feature of this system is the coexistence of precise adaptation in population with large fluctuating cellular behavior in…

Molecular Networks · Quantitative Biology 2019-08-19 Thierry Emonet , Philippe Cluzel

The behaviour of an organism often reflects a strategy for coping with its environment. Such behaviour in higher organisms can often be reduced to a few stereotyped modes of movement due to physiological limitations, but finding such modes…

Cell Behavior · Quantitative Biology 2013-08-26 Luke Tweedy , Börn Meier , Jürgen Stephan , Doris Heinrich , Robert G. Endres

Micro-organisms aggregate through chemotaxis against a concentration gradient of signals secreted by themselves. We have numerically studied a model consisting of elements with intracellular dynamics, random walks with a state-dependent…

Statistical Mechanics · Physics 2007-10-31 Masayo Inoue , Kunihiko Kaneko

Microbial communities are ubiquitous in nature and come in a multitude of forms, ranging from communities dominated by a handful of species to communities containing a wide variety of metabolically distinct organisms. This huge range in…

Biological Physics · Physics 2021-11-02 Amir Erez , Jaime G. Lopez , Yigal Meir , Ned S. Wingreen

Many bacteria rely on active cell appendages, such as type IV pili, to move over substrates and interact with neighboring cells. Here, we study the motion of individual cells and bacterial colonies, mediated by the collective interactions…

Biological Physics · Physics 2019-05-01 Wolfram Pönisch , Christoph A. Weber , Vasily Zaburdaev

Chemotaxis, the directional locomotion of cells towards a source of a chemical gradient, is an integral part of many biological processes - for example, bacteria motion, single-cell or multicellular organisms development, immune response,…

Analysis of PDEs · Mathematics 2021-03-29 Yishu Gong , Alexander Kiselev

The spreading of bacterial populations is central to processes in agriculture, the environment, and medicine. However, existing models of spreading typically focus on cells in unconfined settings--despite the fact that many bacteria inhabit…

Populations and Evolution · Quantitative Biology 2022-06-07 Daniel B. Amchin , Jenna A. Ott , Tapomoy Bhattacharjee , Sujit S. Datta

Ecology and evolution under changing environments are important in many subfields of biology with implications for medicine. Here, we explore an example: the consequences of fluctuating environments on the emergence of antibiotic…

Populations and Evolution · Quantitative Biology 2021-04-13 Bryce Morsky , Dervis Can Vural

We propose two nonlinear random walk models which are suitable for the analysis of both chemotaxis and anomalous transport. We derive the balance equations for the population density for the case when the transition rate for a random walk…

Statistical Mechanics · Physics 2010-10-22 Sergei Fedotov

Despite major environmental and genetic differences, microbial metabolic networks are known to generate consistent physiological outcomes across vastly different organisms. This remarkable robustness suggests that, at least in bacteria,…

Molecular Networks · Quantitative Biology 2022-05-24 Anna Paola Muntoni , Alfredo Braunstein , Andrea Pagnani , Daniele De Martino , Andrea De Martino

Active navigation in disordered media depends on a biased random walk interacting with environmental constraints. Using E. coli chemotactic navigation in agar gels as a model system, we reveal a fundamental trade-off between diffusive…

Soft Condensed Matter · Physics 2025-12-23 Yang Bai , Caiyun He , Weirong Liu , Songtao Cheng , Pan Chu , Liang Luo , Chenli Liu , Xiongfei Fu

We use moving light patterns to control the motion of {\it Escherichia coli} bacteria whose motility is photo-activated. Varying the pattern speed controls the magnitude and direction of the bacterial flux, and therefore the accumulation of…

Microbial interactions regulate their spread and survival in competitive environments. It is not clear if the physical parameters of the environment regulate the outcome of these interactions. In this work, we show that the opportunistic…

Cell Behavior · Quantitative Biology 2023-09-12 Divakar Badal , Aloke Kumar , Varsha Singh , Danny Raj M

Bacterial swimming is well characterized in uniform liquids at rest. The natural habitat of bacterial swimmers, however, is often dominated by moving fluids and interfaces, resulting in shear flows that may strongly alter bacterial…

Various microorganisms and some mammalian cells are able to swim in viscous fluids by performing nonreciprocal body deformations, such as rotating attached flagella or by distorting their entire body. In order to perform chemotaxis, i.e. to…

Biological Physics · Physics 2021-05-06 Benedikt Hartl , Maximilian Hübl , Gerhard Kahl , Andreas Zöttl

Chirality in shape and motility can evolve rapidly in microbes and cancer cells. To determine how chirality affects cell fitness, we developed a model of chiral growth in compact aggregates such as microbial colonies and solid tumors. Our…

Populations and Evolution · Quantitative Biology 2020-07-14 Ashish B. George , Kirill S. Korolev

We investigate the evolution of quiescence within the framework of Adaptive Dynamics for an SIQS (Susceptible - Infected - Quiescent) model with constant environment. In the first part of the paper, the competition of two strains which have…

Populations and Evolution · Quantitative Biology 2025-07-14 Leonard Braun , Noah Risse , Aurélien Tellier , Johannes Müller