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Alzheimer's disease is a neurodegenerative condition that accelerates cognitive decline relative to normal aging. It is of critical scientific importance to gain a better understanding of early disease mechanisms in the brain to facilitate…

Applications · Statistics 2022-01-19 D. Andrew Brown , Christopher S. McMahan , Russell T. Shinohara , Kristin A. Linn

Neuroimaging datasets are rapidly growing in size as a result of advancements in image acquisition methods, open-science and data sharing. However, the adoption of Big Data processing strategies by neuroimaging processing engines remains…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-04-04 Valérie Hayot-Sasson , Shawn T Brown , Tristan Glatard

With the wide adoption of functional magnetic resonance imaging (fMRI) by cognitive neuroscience researchers, large volumes of brain imaging data have been accumulated in recent years. Aggregating these data to derive scientific insights…

Applications · Statistics 2020-06-01 Ming Bo Cai , Michael Shvartsman , Anqi Wu , Hejia Zhang , Xia Zhu

We consider exploratory methods for the discovery of cortical functional connectivity. Typically, data for the i-th subject (i=1...NS) is represented as an NVxNT matrix Xi, corresponding to brain activity sampled at NT moments in time from…

Methodology · Statistics 2011-03-17 Roberto D. Pascual-Marqui , Rolando J. Biscay-Lirio

Single image superresolution has been a popular research topic in the last two decades and has recently received a new wave of interest due to deep neural networks. In this paper, we approach this problem from a different perspective. With…

Computer Vision and Pattern Recognition · Computer Science 2018-10-03 Weifeng Ge , Bingchen Gong , Yizhou Yu

The scale of functional magnetic resonance image data is rapidly increasing as large multi-subject datasets are becoming widely available and high-resolution scanners are adopted. The inherent low-dimensionality of the information in this…

Functional principal component analysis is essential in functional data analysis, but the inferences will become unconvincing when some non-Gaussian characteristics occur, such as heavy tail and skewness. The focus of this paper is to…

Methodology · Statistics 2021-02-02 Rou Zhong , Shishi Liu , Jingxiao Zhang , Haocheng Li

Correlated component analysis as proposed by Dmochowski et al. (2012) is a tool for investigating brain process similarity in the responses to multiple views of a given stimulus. Correlated components are identified under the assumption…

Machine Learning · Statistics 2018-02-08 Simon Kamronn , Andreas Trier Poulsen , Lars Kai Hansen

Characterizing interactions between brain areas is a fundamental goal of systems neuroscience. While such analyses are possible when areas are recorded simultaneously, it is rare to observe all combinations of areas of interest within a…

Neurons and Cognition · Quantitative Biology 2025-10-15 Ji Xia , Yizi Zhang , Shuqi Wang , Genevera I. Allen , Liam Paninski , Cole Lincoln Hurwitz , Kenneth D. Miller

Small sample sizes in neuroimaging in general, and in structural connectome (SC) studies in particular limit the development of reliable biomarkers for neurological and psychiatric disorders - such as Alzheimer's disease and schizophrenia -…

Missingness is a common issue for neuroimaging data, and neglecting it in downstream statistical analysis can introduce bias and lead to misguided inferential conclusions. It is therefore crucial to conduct appropriate statistical methods…

Methodology · Statistics 2025-03-25 Tong Lu , Chixiang Chen , Hsin-Hsiung Huang , Peter Kochunov , Elliot Hong , Shuo Chen

The relation between large-scale brain structure and function is an outstanding open problem in neuroscience. We approach this problem by studying the dynamical regime under which realistic spatio-temporal patterns of brain activity emerge…

Neurons and Cognition · Quantitative Biology 2014-05-27 Ariel Haimovici , Enzo Tagliazucchi , Pablo Balenzuela , Dante R. Chialvo

Fusing structural-functional images of the brain has shown great potential to analyze the deterioration of Alzheimer's disease (AD). However, it is a big challenge to effectively fuse the correlated and complementary information from…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Qiankun Zuo , Junren Pan , Shuqiang Wang

In many neural systems anatomical motifs are present repeatedly, but despite their structural similarity they can serve very different tasks. A prime example for such a motif is the canonical microcircuit of six-layered neo-cortex, which is…

Neurons and Cognition · Quantitative Biology 2015-10-07 Michael Wibral , Viola Priesemann , Jim W. Kay , Joseph T. Lizier , William A. Phillips

While the Segment Anything Model (SAM) excels in semantic segmentation for general-purpose images, its performance significantly deteriorates when applied to medical images, primarily attributable to insufficient representation of medical…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Yiming Zhang , Tianang Leng , Kun Han , Xiaohui Xie

Multi-modal MRIs are widely used in neuroimaging applications since different MR sequences provide complementary information about brain structures. Recent works have suggested that multi-modal deep learning analysis can benefit from…

Computer Vision and Pattern Recognition · Computer Science 2021-06-14 Jiahong Ouyang , Ehsan Adeli , Kilian M. Pohl , Qingyu Zhao , Greg Zaharchuk

Neuroimaging meta-analysis is an important tool for finding consistent effects over studies that each usually have 20 or fewer subjects. Interest in meta-analysis in brain mapping is also driven by a recent focus on so-called "reverse…

Applications · Statistics 2014-12-05 Jian Kang , Thomas E. Nichols , Tor D. Wager , Timothy D. Johnson

We propose a novel technique to assess functional brain connectivity in EEG/MEG signals. Our method, called Sparsely-Connected Sources Analysis (SCSA), can overcome the problem of volume conduction by modeling neural data innovatively with…

Methodology · Statistics 2010-08-05 Stefan Haufe , Ryota Tomioka , Guido Nolte , Klaus-Robert Mueller , Motoaki Kawanabe

Neuroimaging techniques have shown to be useful when studying the brain's activity. This paper uses Magnetoencephalography (MEG) data, provided by the Human Connectome Project (HCP), in combination with various deep artificial neural…

Machine Learning · Computer Science 2020-07-07 Ismail Alaoui Abdellaoui , Jesus Garcia Fernandez , Caner Sahinli , Siamak Mehrkanoon

To understand Working of Human Brain measurements related to the brain function are required. These measurements should be possibly non-invasive. Brain should be disturbed as less as possible during the measurement. Integration of various…

Emerging Technologies · Computer Science 2015-06-16 Revati Shriram , M. Sundhararajan , Nivedita Daimiwal
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