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Quantifying functional connectivity (FC), a vital metric for the diagnosis of various brain disorders, traditionally relies on the use of a pre-defined brain atlas. However, using such atlases can lead to issues regarding selection bias and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Tyler Ward , Abdullah-Al-Zubaer Imran

Atypical Parkinsonian Disorders (APD), also known as Parkinson-plus syndrome, are a group of neurodegenerative diseases that include progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). In the early stages, overlapping…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Mengyu Li , Ingibjörg Kristjánsdóttir , Thilo van Eimeren , Kathrin Giehl , Lotta M. Ellingsen , the ASAP Neuroimaging Initiative

Purpose: Hard-to-interpret Black-box Machine Learning (ML) were often used for early Alzheimer's Disease (AD) detection. Methods: To interpret eXtreme Gradient Boosting (XGBoost), Random Forest (RF), and Support Vector Machine (SVM)…

Machine Learning · Computer Science 2022-11-08 Louise Bloch , Christoph M. Friedrich

Autism Spectrum Disorder (ASD) is a multi-factorial neurodevelopmental disorder, whose causes are still poorly understood. Effective therapies to reduce all the heterogeneous symptoms of the disorder do not exists yet, but behavioural…

Neurons and Cognition · Quantitative Biology 2025-06-02 Elisa Ferrari , Alessandra Retico , Alessandro Cellerino , Davide Bacciu

Autism spectrum disorder (ASD) remains a challenging condition to diagnose effectively and promptly, despite global efforts in public health, clinical screening, and scientific research. Traditional diagnostic methods, primarily reliant on…

Computers and Society · Computer Science 2025-03-11 Nora Fink

A good teaching method is incomprehensible for an autistic child. The autism spectrum disorder is a very diverse phenomenon. It is said that no two autistic children are the same. So, something that works for one child may not be fit for…

Human-Computer Interaction · Computer Science 2023-02-13 Zarin Tassnim Zoana , Mahmudul Wahed Shafeen , Nasrin Akter , Tanvir Rahman

Individuals with Autism Spectrum Disorder (ASD) often experience challenges in health, communication, and sensory processing; therefore, early diagnosis is necessary for proper treatment and care. In this work, we consider the problem of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 M. Serna-Aguilera , X. B. Nguyen , A. Singh , L. Rockers , S. Park , L. Neely , H. Seo , K. Luu

Autism spectrum disorder (ASD) is a developmental disorder characterized by significant social communication impairments and difficulties perceiving and presenting communication cues. Machine learning techniques have been broadly adopted to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Jicheng Li , Vuthea Chheang , Pinar Kullu , Eli Brignac , Zhang Guo , Kenneth E. Barner , Anjana Bhat , Roghayeh Leila Barmaki

Autism, also known as Autism Spectrum Disorder (or ASD), is a neurological disorder. Its main symptoms include difficulty in (verbal and/or non-verbal) communication, and rigid/repetitive behavior. These symptoms are often indistinguishable…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Asha Rani , Pankaj Yadav , Yashaswi Verma

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by impairments in social interaction, communication, as well as restrained or stereotyped behaviors. The inherent heterogeneity within the autism…

Neurons and Cognition · Quantitative Biology 2024-03-28 Caroline Gora , Ana Dudas , Océane Vaugrente , Lucile Drobecq , Emmanuel Pecnard , Gaëlle Lefort , Lucie P. Pellissier

The upper motor neuron dysfunction in amyotrophic lateral sclerosis was quantified using triple stimulation and more focal transcranial magnetic stimulation techniques that were developed to reduce recording variability. These measurements…

Neurons and Cognition · Quantitative Biology 2016-09-29 Rahul Remanan , Viktor Sukhotskiy , Mona Shahbazi , Edward P. Furlani , Dale J. Lange

Autism Spectrum Disorder (ASD) is a pervasive developmental disorder of the central nervous system, primarily manifesting in childhood. It is characterized by atypical and repetitive behaviors. Currently, diagnostic methods mainly rely on…

Neurons and Cognition · Quantitative Biology 2025-03-21 Yiqian Luo , Qiurong Chen , Fali Li , Liang Yi , Peng Xu , Yangsong Zhang

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

The cerebrospinal fluid (CSF) of 19 subjects who received a clinical diagnosis of Alzheimer's disease (AD) as well as of 5 pathological controls have been collected and analysed by Raman spectroscopy (RS). We investigated whether the raw…

Structural magnetic resonance imaging (sMRI) combined with deep learning has achieved remarkable progress in the prediction and diagnosis of Alzheimer's disease (AD). Existing studies have used CNN and transformer to build a well-performing…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Zheng Yang , Yanteng Zhang , Xupeng Kou , Yang Liu , Chao Ren

We performed a PubMed search to find 148 papers published between January 2010 and December 2019 related to human brain, Diffusion Tensor Imaging (DTI), and Machine Learning (ML). The studies focused on healthy cohorts (n = 15), mental…

Machine Learning · Computer Science 2020-12-22 Ashirbani Saha , Pantea Fadaiefard , Jessica E. Rabski , Alireza Sadeghian , Michael D. Cusimano

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder. Finding the biomarkers associated with ASD is extremely helpful to understand the underlying roots of the disorder and can lead to earlier diagnosis and more targeted…

Computer Vision and Pattern Recognition · Computer Science 2018-08-28 Xiaoxiao Li , Nicha C. Dvornek , Juntang Zhuang , Pamela Ventola , James S. Duncan

It is acknowledged that the most common cause of dementia worldwide is Alzheimer's disease (AD). This condition progresses in severity from mild to severe and interferes with people's everyday routines. Early diagnosis plays a critical role…

Image and Video Processing · Electrical Eng. & Systems 2024-09-30 Sajjad Aghasi Javid , Mahmood Mohassel Feghhi

Background: An early diagnosis together with an accurate disease progression monitoring of multiple sclerosis is an important component of successful disease management. Prior studies have established that multiple sclerosis is correlated…

Audio and Speech Processing · Electrical Eng. & Systems 2021-09-28 Emil Svoboda , Tomáš Bořil , Jan Rusz , Tereza Tykalová , Dana Horáková , Charles R. G. Guttman , Krastan B. Blagoev , Hiroto Hatabu , Vlad I. Valtchinov

In recent years, many papers have reported state-of-the-art performance on Alzheimer's Disease classification with MRI scans from the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset using convolutional neural networks. However,…

Image and Video Processing · Electrical Eng. & Systems 2019-06-12 Yi Ren Fung , Ziqiang Guan , Ritesh Kumar , Joie Yeahuay Wu , Madalina Fiterau
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