Quantifying functional connectivity (FC), a vital metric for the diagnosis of various brain disorders, traditionally relies on the use of a pre-defined brain atlas. However, using such atlases can lead to issues regarding selection bias and lack of regard for specificity. Addressing this, we propose a novel transformer-based classification network (ABFR-KAN) with effective brain function representation to aid in diagnosing autism spectrum disorder (ASD). ABFR-KAN leverages Kolmogorov-Arnold Network (KAN) blocks replacing traditional multi-layer perceptron (MLP) components. Thorough experimentation reveals the effectiveness of ABFR-KAN in improving the diagnosis of ASD under various configurations of the model architecture. Our code is available at https://github.com/tbwa233/ABFR-KAN
@article{arxiv.2504.03923,
title = {Improving Brain Disorder Diagnosis with Advanced Brain Function Representation and Kolmogorov-Arnold Networks},
author = {Tyler Ward and Abdullah-Al-Zubaer Imran},
journal= {arXiv preprint arXiv:2504.03923},
year = {2025}
}
Comments
Paper presented orally and as a poster at MIDL 2025