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Related papers: Spatial-Temporal Mitosis Detection in Phase-Contra…

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Detection of mitosis events plays an important role in biomedical research. Deep-learning-based mitosis detection methods have achieved outstanding performance with a certain amount of labeled data. However, these methods require…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Kazuya Nishimura , Ami Katanaya , Shinichiro Chuma , Ryoma Bise

In this paper we propose a workflow to detect and track mitotic cells in time-lapse microscopy image sequences. In order to avoid the requirement for cell lines expressing fluorescent markers and the associated phototoxicity, phase contrast…

Mitotic counts are one of the key indicators of breast cancer prognosis. However, accurate mitotic cell counting is still a difficult problem and is labourious. Automated methods have been proposed for this task, but are usually dependent…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Salar Razavi , Fariba Dambandkhameneh , Dimitri Androutsos , Susan Done , April Khademi

This work presents a mitosis detection method with only one vanilla Convolutional Neural Network (CNN). Our method consists of two steps: given an image, we first apply a CNN using a sliding window technique to extract patches that have…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Hongyan Gu , Mohammad Haeri , Shuo Ni , Christopher Kazu Williams , Neda Zarrin-Khameh , Shino Magaki , Xiang 'Anthony' Chen

Mitotic activity is a crucial proliferation biomarker for the diagnosis and prognosis of different types of cancers. Nevertheless, mitosis counting is a cumbersome process for pathologists, prone to low reproducibility, due to the large…

Image and Video Processing · Electrical Eng. & Systems 2022-12-01 Claudio Fernandez-Martín , Umay Kiraz , Julio Silva-Rodríguez , Sandra Morales , Emiel Janssen , Valery Naranjo

We propose a two-step domain shift-invariant mitosis cell detection method based on Faster RCNN and a convolutional neural network (CNN). We generate various domain-shifted versions of existing histopathology images using a stain…

Computer Vision and Pattern Recognition · Computer Science 2021-09-29 Ramin Nateghi , Fattaneh Pourakpour

Mitotic counting is a vital prognostic marker of tumor proliferation in breast cancer. Deep learning-based mitotic detection is on par with pathologists, but it requires large labeled data for training. We propose a deep classification…

Computer Vision and Pattern Recognition · Computer Science 2020-07-03 Pushpak Pati , Antonio Foncubierta-Rodriguez , Orcun Goksel , Maria Gabrani

The proliferative activity of breast tumors, which is routinely estimated by counting of mitotic figures in hematoxylin and eosin stained histology sections, is considered to be one of the most important prognostic markers. However, mitosis…

Counting mitotic figures is time-intensive for pathologists and leads to inter-observer variability. Artificial intelligence (AI) promises a solution by automatically detecting mitotic figures while maintaining decision consistency.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Seungho Choe , Xiaoli Qin , Abubakr Shafique , Amanda Dy , Susan Done , Dimitrios Androutsos , April Khademi

Counting of mitotic figures is a fundamental step in grading and prognostication of several cancers. However, manual mitosis counting is tedious and time-consuming. In addition, variation in the appearance of mitotic figures causes a high…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Mostafa Jahanifar , Adam Shephard , Neda Zamanitajeddin , Simon Graham , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot

Cell event detection in cell videos is essential for monitoring of cellular behavior over extended time periods. Deep learning methods have shown great success in the detection of cell events for their ability to capture more discriminative…

Computer Vision and Pattern Recognition · Computer Science 2019-09-24 Ha Tran Hong Phan , Ashnil Kumar , David Feng , Michael Fulham , Jinman Kim

For the MIDOG mitosis detection challenge, we created a cascade algorithm consisting of a Mask-RCNN detector, followed by a classification ensemble consisting of ResNet50 and DenseNet201 to refine detected mitotic candidates. The MIDOG…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Gauthier Roy , Jules Dedieu , Capucine Bertrand , Alireza Moshayedi , Ali Mammadov , Stéphanie Petit , Saima Ben Hadj , Rutger H. J. Fick

Mitosis detection is one of the fundamental tasks in computational pathology, which is extremely challenging due to the heterogeneity of mitotic cell. Most of the current studies solve the heterogeneity in the technical aspect by increasing…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Hao Wang , Jiatai Lin , Danyi Li , Jing Wang , Bingchao Zhao , Zhenwei Shi , Xipeng Pan , Huadeng Wang , Bingbing Li , Changhong Liang , Guoqiang Han , Li Liang , Chu Han , Zaiyi Liu

MIDOG 2025 Track 1 requires mitosis detection in whole-slideimages (WSIs) containing non-tumor, inflamed, and necrotic re-gions. Due to the complicated and heterogeneous context, aswell as possible artifacts, there are often false positives…

Image and Video Processing · Electrical Eng. & Systems 2025-09-29 Jie Xiao , Mengye Lyu , Shaojun Liu

The effective localization of mitosis is a critical precursory task for deciding tumor prognosis and grade. Automated mitosis detection through deep learning-oriented image analysis often fails on unseen patient data due to inherent domain…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Tirupati Saketh Chandr , Sahar Almahfouz Nasser , Nikhil Cherian Kurian , Amit Sethi

Mitotic figure count is an important marker of tumor proliferation and has been shown to be associated with patients' prognosis. Deep learning based mitotic figure detection methods have been utilized to automatically locate the cell in…

Computer Vision and Pattern Recognition · Computer Science 2021-09-01 Jingtang Liang , Cheng Wang , Yujie Cheng , Zheng Wang , Fang Wang , Liyu Huang , Zhibin Yu , Yubo Wang

In certain types of cancerous tissue, mitotic count has been shown to be associated with tumor proliferation, poor prognosis, and therapeutic resistance. Due to the high inter-rater variability of mitotic counting by pathologists,…

Computer Vision and Pattern Recognition · Computer Science 2023-10-12 Ruiwen Ding , James Hall , Neil Tenenholtz , Kristen Severson

Domain variability is a common bottle neck in developing generalisable algorithms for various medical applications. Motivated by the observation that the domain variability of the medical images is to some extent compact, we propose to…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Mustaffa Hussain , Ritesh Gangnani , Sasidhar Kadiyala

Mitosis detection is one of the challenging problems in computational pathology, and mitotic count is an important index of cancer grading for pathologists. However, current counts of mitotic nuclei rely on pathologists looking…

Computer Vision and Pattern Recognition · Computer Science 2023-01-19 Huadeng Wang , Hao Xu , Bingbing Li , Xipeng Pan , Lingqi Zeng , Rushi Lan , Xiaonan Luo

We present a novel approach which extends the existing Fully Convolutional One-Stage Object Detector (FCOS) for mitotic figure detection. Our composite model adds a Feedback Attention Ladder CNN (FAL-CNN) model for classification of normal…

Image and Video Processing · Electrical Eng. & Systems 2025-09-22 Andrew Broad , Jason Keighley , Lucy Godson , Alex Wright
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