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Related papers: Spatial-Temporal Mitosis Detection in Phase-Contra…

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Breast cancer is the most commonly diagnosed cancer worldwide, with over two million new cases each year. During diagnostic tumour grading, pathologists manually count the number of dividing cells (mitotic figures) in biopsy or tumour…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Jack Breen , Kieran Zucker , Nicolas M. Orsi , Nishant Ravikumar

Atypical mitotic figures are important biomarkers of tumor aggressiveness in histopathology, yet reliable recognition remains challenging due to severe class imbalance and variability across imaging domains. We present a DenseNet-121-based…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Adinath Dukre , Ankan Deria , Yutong Xie , Imran Razzak

Mitotic count (MC) is an important histological parameter for cancer diagnosis and grading, but the manual process for obtaining MC from whole-slide histopathological images is very time-consuming and prone to error. Therefore, deep…

Computer Vision and Pattern Recognition · Computer Science 2022-03-01 Chawan Piansaddhayanon , Sakun Santisukwongchote , Shanop Shuangshoti , Qingyi Tao , Sira Sriswasdi , Ekapol Chuangsuwanich

Detecting road features is a key enabler for autonomous driving and localization. For instance, a reliable detection of poles which are widespread in road environments can improve localization. Modern deep learning-based perception systems…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Maxime Noizet , Philippe Xu , Philippe Bonnifait

Identification and counting of cells and mitotic figures is a standard task in diagnostic histopathology. Due to the large overall cell count on histological slides and the potential sparse prevalence of some relevant cell types or mitotic…

Computer Vision and Pattern Recognition · Computer Science 2017-09-08 Marc Aubreville , Maximilian Krappmann , Christof Bertram , Robert Klopfleisch , Andreas Maier

Mitotic figure detection is a challenging task in digital pathology that has a direct impact on therapeutic decisions. While automated methods often achieve acceptable results under laboratory conditions, they frequently fail in the…

Image and Video Processing · Electrical Eng. & Systems 2022-01-21 Jakob Dexl , Michaela Benz , Volker Bruns , Petr Kuritcyn , Thomas Wittenberg

Learned object detection methods based on fusion of LiDAR and camera data require labeled training samples, but niche applications, such as warehouse robotics or automated infrastructure, require semantic classes not available in large…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Ryan Rubel , Andrew Dudash , Mohammad Goli , James O'Hara , Karl Wunderlich

Mitotic figures represent a key histoprognostic feature in tumor pathology, providing crucial insights into tumor aggressiveness and proliferation. However, their identification remains challenging, subject to significant inter-observer…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Raphaël Bourgade , Guillaume Balezo , Hana Feki , Lily Monier , Matthieu Blons , Alice Blondel , Delphine Loussouarn , Anne Vincent-Salomon , Thomas Walter

Introduction: Nottingham grading system is a major prognostic factor for invasive breast carcinoma (IBC). Its determination requires the evaluation of the mitotic score (MS) which is subject to low intra- and inter-observer reproducibility.…

Empirical evaluation of breast tissue biopsies for mitotic nuclei detection is considered an important prognostic biomarker in tumor grading and cancer progression. However, automated mitotic nuclei detection poses several challenges…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Anabia Sohail , Muhammad Ahsan Mukhtar , Asifullah Khan , Muhammad Mohsin Zafar , Aneela Zameer , Saranjam Khan

Time series anomaly detection plays a critical role in many dynamic systems. Despite its importance, previous approaches have primarily relied on unimodal numerical data, overlooking the importance of complementary information from other…

Machine Learning · Computer Science 2026-03-24 Shiyan Hu , Jianxin Jin , Yang Shu , Peng Chen , Bin Yang , Chenjuan Guo

Recognizing atypical mitotic figures in histopathology images allows physicians to correctly assess tumor aggressiveness. Although machine learning models could be exploited for automatically performing such a task, under domain shift these…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 Gennaro Percannella , Mattia Sarno , Francesco Tortorella , Mario Vento

Atypical mitotic figures (AMFs) are clinically relevant indicators of abnormal cell division, yet their reliable detection remains challenging due to morphological ambiguity and scanner variability. In this work, we investigated three…

Image and Video Processing · Electrical Eng. & Systems 2025-09-08 Biwen Meng , Xi Long , Jingxin Liu

The difficulty of detecting mitosis and its similarity to non-mitosis objects has remained a challenge in computational pathology. The lack of publicly available data has added more complexity. Deep learning algorithms have shown potentials…

Image and Video Processing · Electrical Eng. & Systems 2021-10-25 Seyed H. Mirjahanmardi , Samir Mitha , Salar Razavi , Susan Done , April Khademi

Bayesian change-point detection, together with latent variable models, allows to perform segmentation over high-dimensional time-series. We assume that change-points lie on a lower-dimensional manifold where we aim to infer subsets of…

Machine Learning · Statistics 2020-11-04 Lorena Romero-Medrano , Pablo Moreno-Muñoz , Antonio Artés-Rodríguez

Accurate Computer-Assisted Diagnosis, relying on large-scale annotated pathological images, can alleviate the risk of overlooking the diagnosis. Unfortunately, in medical imaging, most available datasets are small/fragmented. To tackle…

Computer Vision and Pattern Recognition · Computer Science 2019-08-14 Changhee Han , Yoshiro Kitamura , Akira Kudo , Akimichi Ichinose , Leonardo Rundo , Yujiro Furukawa , Kazuki Umemoto , Yuanzhong Li , Hideki Nakayama

Studies estimate that there will be 266,120 new cases of invasive breast cancer and 40,920 breast cancer induced deaths in the year of 2018 alone. Despite the pervasiveness of this affliction, the current process to obtain an accurate…

Computer Vision and Pattern Recognition · Computer Science 2018-07-06 Siddhant Rao

We present a summary of the domain adaptive cascade R-CNN method for mitosis detection of digital histopathology images. By comprehensive data augmentation and adapting existing popular detection architecture, our proposed method has…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Xi Long , Ying Cheng , Xiao Mu , Lian Liu , Jingxin Liu

Cell detection is the task of detecting the approximate positions of cell centroids from microscopy images. Recently, convolutional neural network-based approaches have achieved promising performance. However, these methods require a…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Kazuya Nishimura , Hyeonwoo Cho , Ryoma Bise

Noisy labels can significantly affect the performance of deep neural networks (DNNs). In medical image segmentation tasks, annotations are error-prone due to the high demand in annotation time and in the annotators' expertise. Existing…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Jiachen Yao , Yikai Zhang , Songzhu Zheng , Mayank Goswami , Prateek Prasanna , Chao Chen