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Spatial Frequency Domain Imaging can map tissue scattering and absorption properties over a wide field of view, making it useful for clinical applications such as wound assessment and surgical guidance. This technique has previously…

Biological Physics · Physics 2021-02-24 Mason T. Chen , Melina Papadakis , Nicholas J. Durr

Synthetic aperture radar (SAR) utilizes an aircraft-carried antenna to emit electromagnetic pulses and detect the returning echoes. As the aircraft travels across a designated area, it synthesizes a large virtual aperture to improve image…

We are now moving into an era where multi-object wide-field surveys, which traditionally use single fibres to observe many targets simultaneously, can exploit compact integral field units in place of single fibres. Current multi-object…

Instrumentation and Methods for Astrophysics · Physics 2015-06-18 Julia Bryant , Joss Bland-Hawthorn , Lisa Fogarty , Jon Lawrence , Scott Croom

The use of individual multimode optical fibers in endoscopy applications has the potential to provide highly miniaturized and noninvasive probes for microscopy and optical micromanipulation. A few different strategies have been proposed…

Single molecule localization microscopy (SMLM) techniques enable imaging biological samples well beyond the diffraction limit of light, but they vary significantly in their spatial and temporal resolutions. High-order statistical analysis…

Biological Physics · Physics 2016-03-15 Shachar Schidorsky , Xiyu Yi , Yair Razvag , Yonatan Golan , Shimon Weiss , Eilon Sherman

We investigate the point spread function of a multimode fiber. The distortion of the focal spot created on the fiber output facet is studied for a variety of the parameters. We develop a theoretical model of wavefront shaping through a…

Optics · Physics 2018-05-18 Adrien Descloux , Lyubov V. Amitonova , Pepijn W. H. Pinkse

When multimode optical fibers are perturbed, the data that is transmitted through them is scrambled. This presents a major difficulty for many possible applications, such as multimode fiber-based telecommunication and endoscopy. To overcome…

Image and Video Processing · Electrical Eng. & Systems 2022-02-17 Shachar Resisi , Sebastien M. Popoff , Yaron Bromberg

The flexible endoscope is a minimally invasive tool in clinical settings, but most of them rely on exogenous staining for diagnosis to provide qualitative information. Here, we demonstrated a flexible endoscopic microscopy (FEM) with…

Significance: Confocal laser scanning enables optical sectioning in fiber bundle endomicroscopy but limits the frame rate. To be able to better explore tissue morphology it is useful to stitch sequentially acquired frames into a mosaic.…

Optics · Physics 2021-07-14 Andrew D. Thrapp , Michael R. Hughes

We present an ultra-thin hybrid imaging system based on an optical multimode fiber (MMF) and an optical fiber hydrophone that combines optical resolution photoacoustic and fluorescence microscopy. To control the illumination at the distal…

The lensless endoscope is a promising device designed to image tissues in vivo at the cellular scale. The traditional acquisition setup consists in raster scanning during which the focused light beam from the optical fiber illuminates…

Computer Vision and Pattern Recognition · Computer Science 2018-10-31 Stéphanie Guérit , Siddharth Sivankutty , Camille Scotté , John Alto Lee , Hervé Rigneault , Laurent Jacques

We propose to use high numerical aperture single mode optical fibers like photonic crystal fiber for lensless in-line holographic microscopy. Highly divergent beam helps to overcome the spatial sampling limitation of the image sensor. In…

Optics · Physics 2020-07-01 Sanjeev Kumar , Manjunatha Mahadevappa , Pranab K. Dutta

In astronomy, multi-object spectrographs employ fibre positioning robots to couple the light from multiple astronomy sources (stars or galaxies) into multiple multi-mode fibres, which are distributed across the focal plane of the telescope.…

Using the shifted-excitation Raman difference spectroscopy technique and an optical fibre featuring a negative curvature excitation core and a coaxial ring of high numerical aperture collection cores, we have developed a portable,…

Progress in neuroscience constantly relies on the development of new techniques to investigate the complex dynamics of neuronal networks. An ongoing challenge is to achieve minimally-invasive and high-resolution observations of neuronal…

Quantitative phase imaging (QPI) is a label-free technique providing both morphology and quantitative biophysical information in biomedicine. However, applying such a powerful technique to in vivo pathological diagnosis remains challenging.…

The current weak lensing measurements of the large scale structure are mostly related to statistical study of background galaxy ellipticities. We consider a possibility to extend lensing studies with intrinsically unresolved sources and…

Astrophysics · Physics 2008-11-26 Asantha Cooray

Bessel beams are non-diffracting light structures, which can be produced with simple tabletop optical elements such as axicon lenses or ring spatial filters and coherent laser beams. One of their main characteristic is that Bessel beams…

For several centuries, far-field optical microscopy has remained a key instrument in many scientific disciplines including physical, chemical and biomedical research. Nonetheless, far-field imaging has many limitations: the spatial…

Optics · Physics 2020-01-27 Lyubov V. Amitonova , Johannes F. de Boer

Following recent advancements in multimode fiber (MMF), miniaturization of imaging endoscopes has proven crucial for minimally invasive surgery in vivo. Recent progress enabled by super-resolution imaging methods with a data-driven deep…

Optics · Physics 2023-07-12 Chuncheng Zhang , Tingting Liu , Zhihua Xie , Yu Wang , Tong Liu , Qian Chen , Xiubao Sui