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We consider the SEIRS epidemiology model with such features of the COVID-19 outbreak as: abundance of unidentified infected individuals, limited time of immunity and a possibility of vaccination. The control of the pandemic dynamics is…

Populations and Evolution · Quantitative Biology 2026-03-31 J. Ilnytskyi , T. Patsahan

Pandemics can bring a range of devastating consequences to public health and the world economy. Identifying the most effective control strategies has been the imperative task all around the world. Various public health control strategies…

Systems and Control · Electrical Eng. & Systems 2021-03-29 Zhe Xu , Xiaoming Duan

This paper revisits a longstanding problem of interest concerning the distributed control of an epidemic process on human contact networks. Due to the stochastic nature and combinatorial complexity of the problem, finding optimal policies…

Optimization and Control · Mathematics 2022-12-12 Mohammad Mubarak , Cameron Nowzari

Metapopulation epidemic models describe epidemic dynamics in networks of spatially distant patches connected with pathways for migration of individuals. In the present study, we deal with a susceptible-infected-recovered (SIR)…

Physics and Society · Physics 2019-08-22 Akari Matsuki , Gouhei Tanaka

This article considers the optimal control of the SIR model with both transmission and treatment uncertainty. It follows the model presented in Gatto and Schellhorn (2021). We make four significant improvements on the latter paper. First,…

Optimization and Control · Mathematics 2021-05-20 Yujia Ding , Henry Schellhorn

A human respiratory syncytial virus surveillance system was implemented in Florida in 1999, to support clinical decision-making for prophylaxis of premature newborns. Recently, a local periodic SEIRS mathematical model was proposed in…

Optimization and Control · Mathematics 2018-10-25 Silverio Rosa , Delfim F. M. Torres

Although modeling studies are focused on the control of SIR-based systems describing epidemic data sets (particularly the COVID-19), few of them present a formal dynamic characterization in terms of equilibrium sets and stability. Such…

Optimization and Control · Mathematics 2021-06-03 A. H. González , A. L. Anderson , A. Ferramosca , E. A. Hernandez-Vargas

Protecting interventions of many types (both pharmaceutical and non-pharmaceutical) can be deployed against the spreading of a communicable disease, as the worldwide COVID-19 pandemic has dramatically shown. Here we investigate in detail…

Physics and Society · Physics 2022-10-14 Romualdo Pastor-Satorras , Claudio Castellano

We study equilibrium distancing during epidemics. Distancing reduces the individual's probability of getting infected but comes at a cost. It creates a single-peaked epidemic, flattens the curve and decreases the size of the epidemic. We…

General Economics · Economics 2021-03-02 Satoshi Fukuda , Nenad Kos , Christoph Wolf

This work focuses on optimal controls of a class of stochastic SIS epidemic models under regime switching. By assuming that a decision maker can either influence the infectivity period or isolate infected individuals, our aim is to minimize…

Optimization and Control · Mathematics 2021-01-12 Ky Tran , George Yin

In this paper, an SIR epidemic model with variable size of population is considered. We study optimal control problem for an SIR model with "vaccination" and "treatment" as controls. It is shown that an optimal control exists. We have…

Optimization and Control · Mathematics 2016-12-28 Olga Klimenkova

Following the emergence of a novel coronavirus (SARS-CoV-2) and its spread outside of China, Europe has experienced large epidemics. In response, many European countries have implemented unprecedented non-pharmaceutical interventions…

The current global health emergency triggered by the pandemic COVID-19 is one of the greatest challenges mankind face in this generation. Computational simulations have played an important role to predict the development of the current…

Populations and Evolution · Quantitative Biology 2020-06-11 Kok Yew Ng , Meei Mei Gui

This paper presents a discrete time probabilistic dynamic for simulating a contact-based epidemic spreading based on discrete time Markov chain process, in particular the attention is addressed to the susceptible-infectious-removed (SIR)…

Physics and Society · Physics 2017-12-22 Fabrizio Angaroni

We apply optimal control theory to a tuberculosis model given by a system of ordinary differential equations. Optimal control strategies are proposed to minimize the cost of interventions, considering reinfection and post-exposure…

Optimization and Control · Mathematics 2013-07-15 Cristiana J. Silva , Delfim F. M. Torres

Governments across the world are currently facing the task of selecting suitable intervention strategies to cope with the effects of the COVID-19 pandemic. This is a highly challenging task, since harsh measures may result in economic…

Optimization and Control · Mathematics 2021-01-19 Andreas Kasis , Stelios Timotheou , Nima Monshizadeh , Marios Polycarpou

We analyze equilibrium behavior and optimal policy within a Susceptible-Infected-Recovered epidemic model augmented with potentially undiagnosed agents who infer their health status and a social planner with imperfect enforcement of social…

Theoretical Economics · Economics 2022-11-01 Thomas Phelan , Alexis Akira Toda

We provide a dynamic policy for the rapid containment of a contagion process modeled as an SIS epidemic on a bounded degree undirected graph with n nodes. We show that if the budget $r$ of curing resources available at each time is…

Social and Information Networks · Computer Science 2014-07-10 Kimon Drakopoulos , Asuman Ozdaglar , John N. Tsitsiklis

The goal of this work is to consider widespread use of face masks as a non-pharmaceutical control strategy for the Covid-19 pandemic. A SEIR model that divides the population into individuals that wear masks and those that do not is…

Populations and Evolution · Quantitative Biology 2021-02-03 João A. M. Gondim

Non-pharmaceutical interventions (NPIs) such as quarantine, self-isolation, social distancing, and virus-contact tracing can greatly reduce the spread of the virus during a pandemic. In the wave of the COVID-19 pandemic, many countries have…

Physics and Society · Physics 2020-12-16 Jingjing He , Xuefei Guan , Xiaochang Duan , Tian Shen , Jing Lin