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Parkinson's disease (PD) is a slowly progressive debilitating neurodegenerative disease which is prominently characterised by motor symptoms. Indoor localisation, including number and speed of room to room transitions, provides a proxy…

Machine Learning · Computer Science 2022-05-13 Ferdian Jovan , Ryan McConville , Catherine Morgan , Emma Tonkin , Alan Whone , Ian Craddock

In this paper, an explainable deep learning-based classifier based on adaptive sinc filters for Parkinson's Disease diagnosis (PD) along with determining its severity, based on analyzing the gait cycle (SincPD) is presented. Considering the…

Signal Processing · Electrical Eng. & Systems 2025-02-26 Armin Salimi-Badr , Mahan Veisi , Sadra Berangi

Surface roughness plays an important role in analyzing engineering surfaces. It quantifies the surface topography and can be used to determine whether the resulting surface finish is acceptable or not. Nevertheless, while several existing…

Signal Processing · Electrical Eng. & Systems 2021-10-20 Melih C. Yesilli , Firas A. Khasawneh

Application and use of deep learning algorithms for different healthcare applications is gaining interest at a steady pace. However, use of such algorithms can prove to be challenging as they require large amounts of training data that…

Machine Learning · Computer Science 2020-05-08 Anirudh Som , Narayanan Krishnamurthi , Matthew Buman , Pavan Turaga

Electrocorticogram (ECoG) well characterizes hand movement intentions and gestures. In the present work we aim to investigate the possibility to enhance hand pose classification, in a Rock-Paper-Scissor - and Rest - task, by introducing…

PPINtonus is a system for the early detection of Parkinson's Disease (PD) utilizing deep-learning tonal analysis, providing a cost-effective and accessible alternative to traditional neurological examinations. Partnering with the…

Audio and Speech Processing · Electrical Eng. & Systems 2024-06-06 Varun Reddy

In recent years, sensors from smart consumer devices have shown great diagnostic potential in movement disorders. In this context, data modalities such as electronic questionnaires, hand movement and voice captures have successfully…

Machine Learning · Computer Science 2022-05-13 Catharina Marie van Alen , Alexander Brenner , Tobias Warnecke , Julian Varghese

Parkinson's disease (PD) is a common neurodegenerative disorder with a poorly understood physiopathology and no established biomarkers for the diagnosis of early stages and for prediction of disease progression. Several neuroimaging…

In recent years, there are many research cases for the diagnosis of Parkinson's disease (PD) with the brain magnetic resonance imaging (MRI) by utilizing the traditional unsupervised machine learning methods and the supervised deep learning…

Image and Video Processing · Electrical Eng. & Systems 2020-03-11 Xiaobo Zhang , Donghai Zhai , Yan Yang , Yiling Zhang , Chunlin Wang

Recently, there has been an explosion in statistical learning literature to represent data using topological principles to capture structure and relationships. We propose a topological data analysis (TDA)-based framework, named Topological…

Machine Learning · Statistics 2025-11-10 Jordan Eckert , Elvan Ceyhan , Henry Schenck

Detecting Parkinson's Disease in its early stages using EEG data presents a significant challenge. This paper introduces a novel approach, representing EEG data as a 15-variate series of bandpower and peak frequency values/coefficients. The…

Neurons and Cognition · Quantitative Biology 2023-12-11 Amarpal Sahota , Amber Roguski , Matthew W. Jones , Michal Rolinski , Alan Whone , Raul Santos-Rodriguez , Zahraa S. Abdallah

Parkinson's disease is a progressive neurodegenerative disorder affecting motor and non-motor functions, with speech impairments among its earliest symptoms. Speech impairments offer a valuable diagnostic opportunity, with machine learning…

Machine Learning · Computer Science 2025-04-25 Lorenzo Simone , Mauro Giuseppe Camporeale , Vito Marco Rubino , Vincenzo Gervasi , Giovanni Dimauro

Deep neural networks have shown potential in analyzing digitized hand-drawn signals for early diagnosis of Parkinson's disease. However, the lack of clear interpretability in existing diagnostic methods presents a challenge to clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Xuechao Wang , Sven Nomm , Junqing Huang , Kadri Medijainen , Aaro Toomela , Michael Ruzhansky

Topological Data Analysis (TDA) has emerged as a powerful framework for extracting robust and interpretable features from noisy high-dimensional data. In the context of Social Choice Theory, where preference profiles and collective…

Algebraic Topology · Mathematics 2025-07-22 Athanasios Andrikopoulos , Nikolaos Sampanis

Alzheimer's disease (AD) emerges from a complex interplay of molecular, cellular, and network-level disturbances that are not easily captured by traditional reductionist frameworks. Conventional analyses of gene expression often rely on…

Quantitative Methods · Quantitative Biology 2025-12-11 Aya Samadzelkava

Parkinson's disease (PD) is a progressive neurodegenerative disorder that impacts motor functions and speech characteristics This study focuses on differentiating individuals with Parkinson's disease from healthy controls through the…

Machine Learning · Computer Science 2025-01-27 Burak Çelik , Ayhan Akbal

Topological Data Analysis (TDA) has emerged as a powerful framework for extracting robust, multiscale, and interpretable features from complex molecular data for artificial intelligence (AI) modeling and topological deep learning (TDL).…

Biomolecules · Quantitative Biology 2025-09-23 JunJie Wee , Jian Jiang

Identifying molecular signatures from complex disease patients with underlying symptomatic similarities is a significant challenge in the analysis of high dimensional multi-omics data. Topological data analysis (TDA) provides a way of…

Genomics · Quantitative Biology 2024-04-23 Davide Gurnari , Aldo Guzmán-Sáenz , Filippo Utro , Aritra Bose , Saugata Basu , Laxmi Parida

In a world abundant with diverse data arising from complex acquisition techniques, there is a growing need for new data analysis methods. In this paper we focus on high-dimensional data that are organized into several hierarchical datasets.…

Machine Learning · Computer Science 2021-04-06 Lior Aloni , Omer Bobrowski , Ronen Talmon

Modern business and economic datasets often exhibit nonlinear, multi-scale structures that traditional linear tools under-represent. Topological Data Analysis (TDA) offers a geometric lens for uncovering robust patterns, such as connected…

Machine Learning · Statistics 2025-11-18 Ioannis Diamantis