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Classical multiple instance learning (MIL) methods are often based on the identical and independent distributed assumption between instances, hence neglecting the potentially rich contextual information beyond individual entities. On the…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Daniel Reisenbüchler , Sophia J. Wagner , Melanie Boxberg , Tingying Peng

Sebocytes are lipid-secreting cells whose differentiation is marked by the accumulation of intracellular lipid droplets, making their quantification a key readout in sebocyte biology. Manual counting is labor-intensive and subjective,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Maryam Adelipour , Gustavo Carneiro , Jeongkwon Kim

In this work, we address the challenge of binary lung nodule classification (benign vs malignant) using CT images by proposing a multi-level attention stacked ensemble of deep neural networks. Three pretrained backbones -- EfficientNet V2…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Uzzal Saha , Surya Prakash

In the real world, medical datasets often exhibit a long-tailed data distribution (i.e., a few classes occupy most of the data, while most classes have rarely few samples), which results in a challenging imbalance learning scenario. For…

Computer Vision and Pattern Recognition · Computer Science 2021-04-23 Lie Ju , Xin Wang , Lin Wang , Tongliang Liu , Xin Zhao , Tom Drummond , Dwarikanath Mahapatra , Zongyuan Ge

Lung cancer is the leading cause of patient mortality in the world. Early diagnosis of malignant pulmonary nodules in CT images can have a significant impact on reducing disease mortality and morbidity. In this work, we propose LMLCC-Net, a…

Image and Video Processing · Electrical Eng. & Systems 2025-11-27 Tasnia Binte Mamun , Adhora Madhuri , Nusaiba Sobir , Taufiq Hasan

The accurate classification of benign and malignant pulmonary nodules in CT scans is critical for early lung cancer screening, yet remains challenging due to the multi-scale and heterogeneous nature of pulmonary nodules. While deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Jinyue Li , Yuzhou Yu , Jingjing Yang , Meng Fu , Yani Zhang , Shuyao He , Dianlong Ge , Xin Ning , Yannan Chu , Qiankun Li

This paper addresses the challenges posed by the unstructured nature and high-dimensional semantic complexity of electronic health record texts. A deep learning method based on attention mechanisms is proposed to achieve unified modeling…

Computation and Language · Computer Science 2025-07-03 Ting Xu , Xiaoxiao Deng , Xiandong Meng , Haifeng Yang , Yan Wu

Automatic pulmonary nodules classification is significant for early diagnosis of lung cancers. Recently, deep learning techniques have enabled remarkable progress in this field. However, these deep models are typically of high computational…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Hanliang Jiang , Fuhao Shen , Fei Gao , Weidong Han

Multiple instance learning (MIL) is a supervised learning methodology that aims to allow models to learn instance class labels from bag class labels, where a bag is defined to contain multiple instances. MIL is gaining traction for learning…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Samuel W. Remedios , Zihao Wu , Camilo Bermudez , Cailey I. Kerley , Snehashis Roy , Mayur B. Patel , John A. Butman , Bennett A. Landman , Dzung L. Pham

Objective: Molecular testing (MT) classifies cytologically indeterminate thyroid nodules as benign or malignant with high sensitivity but low positive predictive value (PPV), only using molecular profiles, ignoring ultrasound (US) imaging…

General point clouds have been increasingly investigated for different tasks, and recently Transformer-based networks are proposed for point cloud analysis. However, there are barely related works for medical point clouds, which are…

Image and Video Processing · Electrical Eng. & Systems 2021-12-20 Jianhui Yu , Chaoyi Zhang , Heng Wang , Dingxin Zhang , Yang Song , Tiange Xiang , Dongnan Liu , Weidong Cai

Multi-instance learning attempts to learn from a training set consisting of labeled bags each containing many unlabeled instances. Previous studies typically treat the instances in the bags as independently and identically distributed.…

Machine Learning · Computer Science 2009-05-13 Zhi-Hua Zhou , Yu-Yin Sun , Yu-Feng Li

We address the problem of supporting radiologists in the longitudinal management of lung cancer. Therefore, we proposed a deep learning pipeline, composed of four stages that completely automatized from the detection of nodules to the…

Image and Video Processing · Electrical Eng. & Systems 2021-03-29 Xavier Rafael-Palou , Anton Aubanell , Mario Ceresa , Vicent Ribas , Gemma Piella , Miguel A. González Ballester

Computed tomography (CT) examinations are commonly used to predict lung nodule malignancy in patients, which are shown to improve noninvasive early diagnosis of lung cancer. It remains challenging for computational approaches to achieve…

Computer Vision and Pattern Recognition · Computer Science 2018-02-07 Jason Causey , Junyu Zhang , Shiqian Ma , Bo Jiang , Jake Qualls , David G. Politte , Fred Prior , Shuzhong Zhang , Xiuzhen Huang

Pulmonary nodule detection using low-dose Computed Tomography (CT) is often the first step in lung disease screening and diagnosis. Recently, algorithms based on deep convolutional neural nets have shown great promise for automated nodule…

Computer Vision and Pattern Recognition · Computer Science 2019-03-26 Hao Tang , Xingwei Liu , Xiaohui Xie

Automatic diagnosing lung cancer from Computed Tomography (CT) scans involves two steps: detect all suspicious lesions (pulmonary nodules) and evaluate the whole-lung/pulmonary malignancy. Currently, there are many studies about the first…

Computer Vision and Pattern Recognition · Computer Science 2019-02-04 Fangzhou Liao , Ming Liang , Zhe Li , Xiaolin Hu , Sen Song

Advances in medical imaging and deep learning have propelled progress in whole slide image (WSI) analysis, with multiple instance learning (MIL) showing promise for efficient and accurate diagnostics. However, conventional MIL models often…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Xianrui Li , Yufei Cui , Jun Li , Antoni B. Chan

We generalize deep self-attention distillation in MiniLM (Wang et al., 2020) by only using self-attention relation distillation for task-agnostic compression of pretrained Transformers. In particular, we define multi-head self-attention…

Computation and Language · Computer Science 2021-06-29 Wenhui Wang , Hangbo Bao , Shaohan Huang , Li Dong , Furu Wei

Classifying chest radiographs is a time-consuming and challenging task, even for experienced radiologists. This provides an area for improvement due to the difficulty in precisely distinguishing between conditions such as pleural effusion,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Maria Efimovich , Jayden Lim , Vedant Mehta , Ethan Poon

Multiple instance learning is qualified for many pattern recognition tasks with weakly annotated data. The combination of artificial neural network and multiple instance learning offers an end-to-end solution and has been widely utilized.…

Computer Vision and Pattern Recognition · Computer Science 2022-05-30 Jingjun Yi , Beichen Zhou