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Air pollution remains a major environmental risk factor that is often associated with adverse health outcomes. However, quantifying and evaluating its effects on human health is challenging due to the complex nature of exposure data. Recent…

Methodology · Statistics 2025-06-02 Soumyakanti Pan , Sudipto Banerjee

Rare cancers affect millions of people worldwide each year. However, estimating incidence or mortality rates associated with rare cancers presents important difficulties and poses new statistical methodological challenges. In this paper, we…

Methodology · Statistics 2025-07-30 Garazi Retegui , Jaione Etxeberria , María Dolores Ugarte

Disease mapping focuses on learning about areal units presenting high relative risk. Disease mapping models for disease counts specify Poisson regressions in relative risks compared with the expected counts. These models typically…

Methodology · Statistics 2016-07-26 Feifei Wang , Jian Wang , Alan E. Gelfand , Fan Li

Income inequality is a major contributor to health disparities, yet its effects often vary by geography and are commonly represented as compositional distributions (e.g., proportions of households across income brackets). Existing spatial…

Methodology · Statistics 2026-05-18 Jingwen Deng , Shujie Ma , Sergio J. Rey , Guanyu Hu

Automated learning of patients demographics can be seen as multi-label problem where a patient model is based on different race and gender groups. The resulting model can be further integrated into Privacy-Preserving Data Mining, where it…

Machine Learning · Computer Science 2015-03-27 Naveen Kumar Parachur Cotha , Marina Sokolova

In low- and middle-income countries (LMICs), accurate estimates of subnational health and demographic indicators are critical for guiding policy and identifying disparities. Many indicators of interest are proportions of binary outcomes and…

Applications · Statistics 2025-06-23 Jon Wakefield , Peter A. Gao , Geir-Arne Fuglstad , Zehang Richard Li

Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…

Machine Learning · Computer Science 2025-03-04 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo

To complement traditional dietary surveys, which are costly and of limited scale, researchers have resorted to digital data to infer the impact of eating habits on people's health. However, online studies are limited in resolution: they are…

Computers and Society · Computer Science 2019-05-02 Luca Maria Aiello , Rossano Schifanella , Daniele Quercia , Lucia Del Prete

Illness-death models are a class of stochastic models inside the multi-state framework. In those models, individuals are allowed to move over time between different states related to illness and death. They are of special interest when…

Applications · Statistics 2022-10-14 Fran Llopis-Cardona , Carmen Armero , Gabriel Sanfélix-Gimeno

Multimorbidity, the co-occurrence of two or more chronic diseases such as diabetes, obesity or cardiovascular diseases in one patient, is a frequent phenomenon. To make care more efficient, it is of relevance to understand how different…

Medical Physics · Physics 2019-08-05 Nils Haug , Stefan Thurner , Alexandra Kautzky-Willer , Michael Gyimesi , Peter Klimek

Disease mapping attempts to explain observed health event counts across areal units, typically using Markov random field models. These models rely on spatial priors to account for variation in raw relative risk or rate estimates. Spatial…

Methodology · Statistics 2025-10-03 Garazi Retegui , Alan E. Gelfand , Jaione Etxeberria , María Dolores Ugarte

Several methods have been proposed in the spatial statistics literature for the analysis of big data sets in continuous domains. However, new methods for analyzing high-dimensional areal data are still scarce. Here, we propose a scalable…

Methodology · Statistics 2021-02-26 E. Orozco-Acosta , A. Adin , M. D. Ugarte

Many scientific applications involve mixed spatially indexed outcomes of heterogeneous types that are driven by shared latent mechanisms. Modeling such data is challenging due to complex, nonlinear, and potentially nonstationary spatial…

Methodology · Statistics 2026-03-10 Yeseul Jeon , Kyeong Eun Lee , Joon Jin Song

The classical multilevel model fails to capture the proximity effect in epidemiological studies, where subjects are nested within geographical units. Multilevel Conditional Autoregressive models are alternatives to help explain the spatial…

Methodology · Statistics 2021-11-24 Dany Djeudeu , Susanne Moebus , Katja Ickstadt

We investigate joint modeling of longevity trends using the spatial statistical framework of Gaussian Process regression. Our analysis is motivated by the Human Mortality Database (HMD) that provides unified raw mortality tables for nearly…

Applications · Statistics 2020-03-06 Nhan Huynh , Mike Ludkovski

We develop a Bayesian bivariate spatial model for multivariate regression analysis applicable to studies examining the influence of genetic variation on brain structure. Our model is motivated by an imaging genetics study of the Alzheimer's…

Methodology · Statistics 2020-05-26 Yin Song , Shufei Ge , Jiguo Cao , Liangliang Wang , Farouk S. Nathoo

This work focuses on the mixed membership models for multivariate categorical data widely used for analyzing survey responses and population genetics data. These grade of membership (GoM) models offer rich modeling power but present…

Methodology · Statistics 2024-12-30 Ling Chen , Chengzhu Huang , Yuqi Gu

In this work, we propose a new Bayesian spatial homogeneity pursuit method for survival data under the proportional hazards model to detect spatially clustered patterns in baseline hazard and regression coefficients. Specially, regression…

Applications · Statistics 2021-02-24 Lijiang Geng , Guanyu Hu

In recent years, disease mapping studies have become a routine application within geographical epidemiology and are typically analysed within a Bayesian hierarchical model formulation. A variety of model formulations for the latent level…

Methodology · Statistics 2016-01-07 Andrea Riebler , Sigrunn H. Sørbye , Daniel Simpson , Håvard Rue

Case vs control comparisons have been the classical approach to the study of neurological diseases. However, most patients will not fall cleanly into either group. Instead, clinicians will typically find patients that cannot be classified…

Machine Learning · Statistics 2012-07-20 Iead Rezek , Christian Beckmann