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Medical events of interest, such as mortality, often happen at a low rate in electronic medical records, as most admitted patients survive. Training models with this imbalance rate (class density discrepancy) may lead to suboptimal…

Machine Learning · Computer Science 2022-08-02 Zepeng Huo , Xiaoning Qian , Shuai Huang , Zhangyang Wang , Bobak J. Mortazavi

In this work, we propose to tackle the problem of domain generalization in the context of \textit{insufficient samples}. Instead of extracting latent feature embeddings based on deterministic models, we propose to learn a domain-invariant…

Machine Learning · Computer Science 2024-02-12 Kecheng Chen , Elena Gal , Hong Yan , Haoliang Li

Two-sample summary-data Mendelian randomization (MR) has become a popular research design to estimate the causal effect of risk exposures. With the sample size of GWAS continuing to increase, it is now possible to utilize genetic…

Applications · Statistics 2018-11-20 Qingyuan Zhao , Yang Chen , Jingshu Wang , Dylan S. Small

The success and generalisation of deep learning algorithms heavily depend on learning good feature representations. In medical imaging this entails representing anatomical information, as well as properties related to the specific imaging…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Agisilaos Chartsias , Thomas Joyce , Giorgos Papanastasiou , Scott Semple , Michelle Williams , David Newby , Rohan Dharmakumar , Sotirios A. Tsaftaris

Time elapsed till an event of interest is often modeled using the survival analysis methodology, which estimates a survival score based on the input features. There is a resurgence of interest in developing more accurate prediction models…

Machine Learning · Computer Science 2024-07-23 Navid Seidi , Ardhendu Tripathy , Sajal K. Das

Long-term adherence to medication is a critical factor in preventing chronic diseases, such as cardiovascular disease. To address poor adherence, physicians may recommend adherence-improving interventions; however, such interventions are…

Optimization and Control · Mathematics 2026-02-24 Daniel Otero-Leon , Mariel Lavieri , Brian Denton , Jeremy Sussman , Rodney Hayward

The vast amount of health data has been continuously collected for each patient, providing opportunities to support diverse healthcare predictive tasks such as seizure detection and hospitalization prediction. Existing models are mostly…

Machine Learning · Computer Science 2023-02-16 Chaoqi Yang , M. Brandon Westover , Jimeng Sun

Access to healthy food is key to maintaining a healthy lifestyle and can be quantified by the distance to the nearest grocery store. However, calculating this distance forces a trade-off between cost and correctness. Accurate route-based…

Methodology · Statistics 2025-10-17 Ashley E. Mullan , P. D. Anh Nguyen , Sarah C. Lotspeich

Multivariate data that combine binary, categorical, count and continuous outcomes are common in the social and health sciences. We propose a semiparametric Bayesian latent variable model for multivariate data of arbitrary type that does not…

Applications · Statistics 2014-01-14 Jonathan Gruhl , Elena A. Erosheva , Paul K. Crane

Medical data range from genomic sequences and retinal photographs to structured laboratory results and unstructured clinical narratives. Although these modalities appear disparate, many encode convergent information about a single…

Quantitative Methods · Quantitative Biology 2025-06-06 Salil Patel

Diabetes is considered a lifestyle disease and a well managed self-care plays an important role in the treatment. Clinicians often conduct surveys to understand the self-care behaviors in their patients. In this context, we propose to use…

Computational Engineering, Finance, and Science · Computer Science 2015-03-29 Santosh Tirunagari , Norman Poh , Guosheng Hu , David Windridge

The appropriateness of the Poisson model is frequently challenged when examining spatial count data marked by unbalanced distributions, over-dispersion, or under-dispersion. Moreover, traditional parametric models may inadequately capture…

Methodology · Statistics 2025-03-26 Mahsa Nadifar , Andriette Bekker , Mohammad Arashi , Abel Ramoelo

Joint models for longitudinal and survival data have become a popular framework for studying the association between repeatedly measured biomarkers and clinical events. Nevertheless, addressing complex survival data structures, especially…

Joint modeling of longitudinal and survival data has become increasingly important in medical research, particularly for understanding disease progression in chronic conditions where both repeated biomarker measurements and time-to-event…

Methodology · Statistics 2025-12-30 Nithisha Suryadevara , Vivek Reddy Srigiri

Personalized longitudinal disease assessment is central to quickly diagnosing, appropriately managing, and optimally adapting the therapeutic strategy of multiple sclerosis (MS). It is also important for identifying the idiosyncratic…

Road traffic casualties represent a hidden global epidemic, demanding evidence-based interventions. This paper demonstrates a network lattice approach for identifying road segments of particular concern, based on a case study of a major…

Applications · Statistics 2023-03-13 Andrea Gilardi , Jorge Mateu , Riccardo Borgoni , Robin Lovelace

Understanding how and why certain communities bear a disproportionate burden of disease is challenging due to the scarcity of data on these communities. Surveys provide a useful avenue for accessing hard-to-reach populations, as many…

Methodology · Statistics 2023-07-27 Stephanie M. Wu , Briana Joy K. Stephenson

Cancer is a significant health issue globally and it is well known that cancer risk varies geographically. However in many countries there are no small area level data on cancer risk factors with high resolution and complete reach, which…

Applications · Statistics 2024-03-04 James Hogg , Jessica Cameron , Susanna Cramb , Peter Baade , Kerrie Mengersen

The management of hyperglycemia in hospitalized patients has a significant impact on both morbidity and mortality. Therefore, it is important to predict the need for diabetic patients to be hospitalized. However, using standard machine…

Artificial Intelligence · Computer Science 2022-08-02 Shaina Raza

The problem we consider considers estimating a multivariate longitudinal panel data model whose outcomes can be a combination of discrete and continuous variables. This problem is challenging because the likelihood is usually analytically…

Methodology · Statistics 2017-09-26 David Gunawan , Chris carter , Denzil Fiebig , Robert Kohn
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