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Background: Lung cancer was known as primary cancers and the survival rate of cancer is about 15%. Early detection of lung cancer is the leading factor in survival rate. All symptoms (features) of lung cancer do not appear until the cancer…

Artificial Intelligence · Computer Science 2016-01-26 Mitra Montazeri , Mahdieh Soleymani Baghshah , Ahmad Enhesari

By combining various cancer cell line (CCL) drug screening panels, the size of the data has grown significantly to begin understanding how advances in deep learning can advance drug response predictions. In this paper we train >35,000…

The ability to generalize to unseen domains is crucial for machine learning systems deployed in the real world, especially when we only have data from limited training domains. In this paper, we propose a simple and effective regularization…

Machine Learning · Computer Science 2023-12-06 Zhenmei Shi , Yifei Ming , Ying Fan , Frederic Sala , Yingyu Liang

Kernel-based feature selection is an important tool in nonparametric statistics. Despite many practical applications of kernel-based feature selection, there is little statistical theory available to support the method. A core challenge is…

Statistics Theory · Mathematics 2022-05-26 Feng Ruan , Keli Liu , Michael I. Jordan

Learning tasks such as those involving genomic data often poses a serious challenge: the number of input features can be orders of magnitude larger than the number of training examples, making it difficult to avoid overfitting, even when…

Radiation response in cancer is shaped by complex, patient specific biology, yet current treatment strategies often rely on uniform dose prescriptions without accounting for tumor heterogeneity. In this study, we introduce a meta learning…

Medical Physics · Physics 2025-08-12 Hao Peng , Yuanyuan Zhang , Steve Jiang , Robert Timmerman , John Minna

Despite the advances in medicine, cancer has remained a formidable challenge. Particularly in the case of pancreatic tumors, characterized by their diversity and late diagnosis, early detection poses a significant challenge crucial for…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Reza Babaei , Samuel Cheng , Theresa Thai , Shangqing Zhao

This paper presents a novel kernel-based generative classifier which is defined in a distortion subspace using polynomial series expansion, named Kernel-Distortion (KD) classifier. An iterative kernel selection algorithm is developed to…

Machine Learning · Statistics 2016-06-22 Bo Tang , Paul M. Baggenstoss , Haibo He

With too few samples or too many model parameters, overfitting can inhibit the ability to generalise predictions to new data. Within medical imaging, this can occur when features are incorrectly assigned importance such as distinct hospital…

Computer Vision and Pattern Recognition · Computer Science 2019-07-31 Becks Simpson , Francis Dutil , Yoshua Bengio , Joseph Paul Cohen

Kernel methods have achieved very good performance on large scale regression and classification problems, by using the Nystr\"om method and preconditioning techniques. The Nystr\"om approximation -- based on a subset of landmarks -- gives a…

Machine Learning · Computer Science 2020-02-21 Michaël Fanuel , Joachim Schreurs , Johan A. K. Suykens

In the last decade, a considerable research effort has been devoted to developing adaptive algorithms based on kernel functions. One of the main features of these algorithms is that they form a family of universal approximation techniques,…

Signal Processing · Electrical Eng. & Systems 2018-08-21 A. Flores , R. C. de Lamare

We develop a feature allocation model for inference on genetic tumor variation using next-generation sequencing data. Specifically, we record single nucleotide variants (SNVs) based on short reads mapped to human reference genome and…

Applications · Statistics 2015-09-15 Juhee Lee , Peter Müller , Kamalakar Gulukota , Yuan Ji

Characterization of lung nodules as benign or malignant is one of the most important tasks in lung cancer diagnosis, staging and treatment planning. While the variation in the appearance of the nodules remains large, there is a need for a…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Sarfaraz Hussein , Robert Gillies , Kunlin Cao , Qi Song , Ulas Bagci

Kernel methods represent one of the most powerful tools in machine learning to tackle problems expressed in terms of function values and derivatives due to their capability to represent and model complex relations. While these methods show…

Statistics Theory · Mathematics 2015-11-06 Bharath K. Sriperumbudur , Zoltan Szabo

Amidst the array of quantum machine learning algorithms, the quantum kernel method has emerged as a focal point, primarily owing to its compatibility with noisy intermediate-scale quantum devices and its promise to achieve quantum…

Quantum Physics · Physics 2024-09-13 Shahram Dehdashti , Prayag Tiwari , Kareem H. El Safty , Peter Bruza , Janis Notzel

The diagnosis of brain tumours is an extremely sensitive and complex clinical task that must rely upon information gathered through non-invasive techniques. One such technique is magnetic resonance, in the modalities of imaging or…

Image and Video Processing · Electrical Eng. & Systems 2025-03-13 Carlos Arizmendi , Alfredo Vellido , Enrique Romero

Background Precise prediction of cancer types is vital for cancer diagnosis and therapy. Important cancer marker genes can be inferred through predictive model. Several studies have attempted to build machine learning models for this task…

Genomics · Quantitative Biology 2019-06-20 Milad Mostavi , Yu-Chiao Chiu , Yufei Huang , Yidong Chen

In this paper we propose a classification scheme to isolate truly benign tumors from those that initially start off as benign but subsequently show metastases. A non-parametric artificial neural network methodology has been chosen because…

General Mathematics · Mathematics 2007-05-23 M. Khoshnevisan , Sukanto Bhattacharya , Florentin Smarandache

Lung cancer is one of the prevalence diseases in the world which cause many deaths. Detecting early stages of lung cancer is so necessary. So, modeling and simulating some intelligent medical systems is an essential which can help…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Ehsan Sadeghi Pour , Mahdi Esmaeili

Quantum algorithms based on quantum kernel methods have been investigated previously [1]. A quantum advantage is derived from the fact that it is possible to construct a family of datasets for which, only quantum processing can recognise…

Quantum Physics · Physics 2024-05-08 Sanjeev Naguleswaran