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Motivation. Understanding the pan-cancer mutational landscape offers critical insights into the molecular mechanisms underlying tumorigenesis. While patient-level machine learning techniques have been widely employed to identify tumor…

Machine Learning · Computer Science 2025-08-29 Yifan Dou , Adam Khadre , Ruben C Petreaca , Golrokh Mirzaei

Tumor growth prediction, a highly challenging task, has long been viewed as a mathematical modeling problem, where the tumor growth pattern is personalized based on imaging and clinical data of a target patient. Though mathematical models…

Computer Vision and Pattern Recognition · Computer Science 2017-06-05 Ling Zhang , Le Lu , Ronald M. Summers , Electron Kebebew , Jianhua Yao

In the field of data mining, how to deal with high-dimensional data is an inevitable problem. Unsupervised feature selection has attracted more and more attention because it does not rely on labels. The performance of spectral-based…

Machine Learning · Computer Science 2021-01-01 Zhengxin Li , Feiping Nie , Jintang Bian , Xuelong Li

We propose a tree regularization framework, which enables many tree models to perform feature selection efficiently. The key idea of the regularization framework is to penalize selecting a new feature for splitting when its gain (e.g.…

Machine Learning · Computer Science 2012-03-22 Houtao Deng , George Runger

Linearization of attention using various kernel approximation and kernel learning techniques has shown promise. Past methods used a subset of combinations of component functions and weight matrices within the random feature paradigm. We…

Machine Learning · Computer Science 2025-09-24 Duke Nguyen , Du Yin , Aditya Joshi , Flora Salim

Machine learning and quantum computing are two technologies each with the potential for altering how computation is performed to address previously untenable problems. Kernel methods for machine learning are ubiquitous for pattern…

In supervised machine learning, feature selection plays a very important role by potentially enhancing explainability and performance as measured by computing time and accuracy-related metrics. In this paper, we investigate a method for…

Machine Learning · Computer Science 2024-02-02 Raisa Islam , Subhasish Mazumdar , Rakibul Islam

In this work, we introduce kernels with random Fourier features in the meta-learning framework to leverage their strong few-shot learning ability. We propose meta variational random features (MetaVRF) to learn adaptive kernels for the…

Machine Learning · Computer Science 2020-08-14 Xiantong Zhen , Haoliang Sun , Yingjun Du , Jun Xu , Yilong Yin , Ling Shao , Cees Snoek

This study presents a convolutional neural network (CNN)-based approach for the multi-class classification of brain tumors using magnetic resonance imaging (MRI) scans. We utilize a publicly available dataset containing MRI images…

Image and Video Processing · Electrical Eng. & Systems 2025-05-07 Natnael Alemayehu

Gene expression analysis aims at identifying the genes able to accurately predict biological parameters like, for example, disease subtyping or progression. While accurate prediction can be achieved by means of many different techniques,…

Methodology · Statistics 2008-09-11 Christine De Mol , Sofia Mosci , Magali Traskine , Alessandro Verri

Definitive cancer diagnosis and management depend upon the extraction of information from microscopy images by pathologists. These images contain complex information requiring time-consuming expert human interpretation that is prone to…

Cancer and its subtypes constitute approximately 30% of all causes of death globally and display a wide range of heterogeneity in terms of clinical and molecular responses to therapy. Molecular subtyping has enabled the use of precision…

Quantitative Methods · Quantitative Biology 2024-07-11 Anwar Khan , Boreom Lee

Improvement of statistical learning models in order to increase efficiency in solving classification or regression problems is still a goal pursued by the scientific community. In this way, the support vector machine model is one of the…

Machine Learning · Statistics 2019-11-22 Anderson Ara , Mateus Maia , Samuel Macêdo , Francisco Louzada

Kernel pruning methods have been proposed to speed up, simplify, and improve explanation of convolutional neural network (CNN) models. However, the effectiveness of a simplified model is often below the original one. In this letter, we…

Machine Learning · Computer Science 2021-08-19 D. Osaku , J. F. Gomes , A. X. Falcão

Recently the use of Noisy Intermediate Scale Quantum (NISQ) devices for machine learning tasks has been proposed. The propositions often perform poorly due to various restrictions. However, the quantum devices should perform well in…

Quantum Physics · Physics 2019-07-12 Przemysław Sadowski

Recent years have demonstrated that using random feature maps can significantly decrease the training and testing times of kernel-based algorithms without significantly lowering their accuracy. Regrettably, because random features are…

Machine Learning · Computer Science 2015-04-08 Jiyan Yang , Alex Gittens

We discuss a cancer hallmark network framework for modelling genome-sequencing data to predict cancer clonal evolution and associated clinical phenotypes. Strategies of using this framework in conjunction with genome sequencing data in an…

Molecular Networks · Quantitative Biology 2014-08-12 Edwin Wang , Naif Zaman , Shauna Mcgee , Jean-Sébastien Milanese , Ali Masoudi-Nejad , Maureen O'Connor

We study in this paper a smoothness regularization method for functional linear regression and provide a unified treatment for both the prediction and estimation problems. By developing a tool on simultaneous diagonalization of two positive…

Statistics Theory · Mathematics 2012-11-13 Ming Yuan , T. Tony Cai

Gradient based meta-learning methods are prone to overfit on the meta-training set, and this behaviour is more prominent with large and complex networks. Moreover, large networks restrict the application of meta-learning models on low-power…

Machine Learning · Computer Science 2022-06-06 Arnav Chavan , Rishabh Tiwari , Udbhav Bamba , Deepak K. Gupta

Kernel method has been developed as one of the standard approaches for nonlinear learning, which however, does not scale to large data set due to its quadratic complexity in the number of samples. A number of kernel approximation methods…

Machine Learning · Computer Science 2018-09-20 Lingfei Wu , Ian E. H. Yen , Jie Chen , Rui Yan
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