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We present a data-driven optimal control approach which integrates the reported partial data with the epidemic dynamics for COVID-19. We use a basic Susceptible-Exposed-Infectious-Recovered (SEIR) model, the model parameters are…

Optimization and Control · Mathematics 2020-12-22 Hailiang Liu , Xuping Tian

In this paper, we propose a Susceptible-Infected-Removal (SIR) model with time fused coefficients. In particular, our proposed model discovers the underlying time homogeneity pattern for the SIR model's transmission rate and removal rate…

Applications · Statistics 2021-03-11 Hou-Cheng Yang , Yishu Xue , Yuqing Pan , Qingyang Liu , Guanyu Hu

This paper studies algorithmic strategies to effectively reduce the number of infections in susceptible-infected-recovered (SIR) epidemic models. We consider a Markov chain SIR model and its two instantiations in the deterministic SIR…

Optimization and Control · Mathematics 2020-11-24 Yuhao Yi , Liren Shan , Philip E. Paré , Karl H. Johansson

Graph convolutional neural networks (GCNs) have shown tremendous promise in addressing data-intensive challenges in recent years. In particular, some attempts have been made to improve predictions of Susceptible-Infected-Recovered (SIR)…

Machine Learning · Statistics 2025-01-07 Petr Kisselev , Padmanabhan Seshaiyer

We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…

Populations and Evolution · Quantitative Biology 2020-06-09 Evangelos Magirou

A linearization-based feedback-control strategy for a SEIR epidemic model is discussed. The vaccination objective is the asymptotically tracking of the removed-by-immunity population to the total population while achieving simultaneously…

Dynamical Systems · Mathematics 2011-03-24 M. De la Sen , A. Ibeas , S. Alonso-Quesada

Governments across the world are currently facing the task of selecting suitable intervention strategies to cope with the effects of the COVID-19 pandemic. This is a highly challenging task, since harsh measures may result in economic…

Optimization and Control · Mathematics 2021-01-19 Andreas Kasis , Stelios Timotheou , Nima Monshizadeh , Marios Polycarpou

We introduce an epidemic spreading model on a network using concepts from percolation theory. The model is motivated by discussing the standard SIR model, with extensions to describe effects of lockdowns within a population. The underlying…

Physics and Society · Physics 2020-08-26 Fabrizio Croccolo , H. Eduardo Roman

The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has led to a wide range of non-pharmaceutical interventions being implemented around the world to curb transmission. However, the economic and social costs of some of these…

Quantitative Methods · Quantitative Biology 2022-04-29 Cameron A. Smith , Christian A. Yates , Ben Ashby

Disease transmission is studied through disciplines like epidemiology, applied mathematics, and statistics. Mathematical simulation models for transmission have implications in solving public and personal health challenges. The SIR model…

Populations and Evolution · Quantitative Biology 2022-01-04 R. Jayatilaka , R. Patel , M. Brar , Y. Tang , N. M. Jisrawi , F. Chishtie , J. Drozd , S. R. Valluri

The spread of COVID-19 has been thwarted in most countries through non-pharmaceutical interventions. In particular, the most effective measures in this direction have been the stay-at-home and closure strategies of businesses and schools.…

Physics and Society · Physics 2022-05-04 G. Dimarco , G. Toscani , M. Zanella

We investigate final outcome properties of an SIR (susceptible $\to$ infective $\to$ recovered) epidemic model defined on a population of large sub-communities in which there is stronger disease transmission within the communities than…

Probability · Mathematics 2024-04-08 Frank Ball , David Sirl , Pieter Trapman

An epidemiological study of deaths is carried out in a dozen countries by analyzing the first wave of the COVID-19 pandemic. These countries are among those most affected by the first wave, i.e. where daily-death data series may closely…

Populations and Evolution · Quantitative Biology 2023-06-22 J. E. Amaro

Accurate forecasts of the number of newly infected people during an epidemic are critical for making effective timely decisions. This paper addresses this challenge using the SIMLR model, which incorporates machine learning (ML) into the…

Machine Learning · Computer Science 2021-06-04 Roberto Vega , Leonardo Flores , Russell Greiner

In this research, we develop a framework to analyze the interaction between the economy and the Covid-19 pandemic using an extension of SIR epidemic model. At the outset, we assume there are two health related investments including general…

Optimization and Control · Mathematics 2022-02-14 Zachariah Sinkala , Vajira Manathunga , Bichaka Fayissa

The presence of a large number of infected individuals with few or no symptoms is an important epidemiological difficulty and the main mathematical feature of COVID-19. The A-SIR model, i.e. a SIR (Susceptible-Infected-Removed) model with a…

Populations and Evolution · Quantitative Biology 2020-08-19 Armando G. M. Neves , Gustavo Guerrero

Coronavirus COVID-19 spreads through the population mostly based on social contact. To gauge the potential for widespread contagion, to cope with associated uncertainty and to inform its mitigation, more accurate and robust modelling is…

This paper studies the distribution function of the time of extinction of a subcritical epidemic, when a large enough proportion of the population has been immunized and/or the infectivity of the infectious individuals has been reduced, so…

Probability · Mathematics 2023-04-05 Anicet Mougabe-Peurkor , Ibrahima Drame , Modeste N'zi , Etienne Pardoux

We present modeling of the COVID-19 epidemic in Illinois, USA, capturing the implementation of a Stay-at-Home order and scenarios for its eventual release. We use a non-Markovian age-of-infection model that is capable of handling long and…

Populations and Evolution · Quantitative Biology 2020-11-25 George N. Wong , Zachary J. Weiner , Alexei V. Tkachenko , Ahmed Elbanna , Sergei Maslov , Nigel Goldenfeld

Containing an epidemic at its origin is the most desirable mitigation. Epidemics have often originated in rural areas, with rural communities among the first affected. Disease dynamics in rural regions have received limited attention, and…