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Epilepsy is one of the most prevalent brain disorders that disrupts the lives of millions worldwide. For patients with drug-resistant seizures, there exist implantable devices capable of monitoring neural activity, promptly triggering…

Signal Processing · Electrical Eng. & Systems 2023-10-31 Arman Zarei , Bingzhao Zhu , Mahsa Shoaran

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

Neurons and Cognition · Quantitative Biology 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett

Epilepsy is one of the most occurring neurological disease globally emerged back in 4000 BC. It is affecting around 50 million people of all ages these days. The trait of this disease is recurrent seizures. In the past few decades, the…

Machine Learning · Computer Science 2021-11-08 Virender Ranga , Shivam Gupta , Jyoti Meena , Priyansh Agrawal

Epilepsy is a chronic neurological disorder affecting more than 65 million people worldwide and manifested by recurrent unprovoked seizures. The unpredictability of seizures not only degrades the quality of life of the patients, but it can…

Signal Processing · Electrical Eng. & Systems 2019-11-13 Damian Pascual , Amir Aminifar , David Atienza , Philippe Ryvlin , Roger Wattenhofer

Analyzing neural data such as Electroencephalography (EEG) data often involves dealing with high-dimensional datasets, where not all channels provide equally meaningful informa- tion. Selecting the most relevant channels is crucial for…

Signal Processing · Electrical Eng. & Systems 2025-10-16 Neda Abdollahpour , N. Sertac Artan , Ian Daly , Mohammadreza Yazdchi , Zahra Baharlouei

Epileptic seizure detection and classification in clinical electroencephalogram data still is a challenge, and only low sensitivity with a high rate of false positives has been achieved with commercially available seizure detection tools,…

Signal Processing · Electrical Eng. & Systems 2020-07-14 Tomas Iesmantas , Robertas Alzbutas

Emotion regulation plays a key role in human behavior and overall well-being. Neurofeedback is a non-invasive self-brain training technique used for emotion regulation to enhance brain function and treatment of mental disorders through…

Neurons and Cognition · Quantitative Biology 2023-11-06 Amin Dehghani , Hamid Soltanian-Zadeh , Gholam-Ali Hossein-Zadeh

An ability to map seizure-generating brain tissue, i.e., the seizure onset zone (SOZ), without recording actual seizures could reduce the duration of invasive EEG monitoring for patients with drug-resistant epilepsy. A widely-adopted…

The underlying dynamics for the electroencephalographic (EEG) recordings from humans but especially epilepsy patients are usually not completely known. However, the ictal activity is claimed to be characterized by synchronous oscillations…

Biological Physics · Physics 2010-08-09 Caglar Tuncay

The electrical stimulation to the seizure onset zone (SOZ) serves as an efficient approach to seizure suppression. Recently, seizure dynamics have gained widespread attendance in its network propagation mechanisms. Compared with the direct…

Neurons and Cognition · Quantitative Biology 2024-06-17 Zhichao Liang , Guanyi Zhao , Yinuo Zhang , Weiting Sun , Jingzhe Lin , Jialin Wang , Quanying Liu

The brain is a high-dimensional directional network system consisting of many regions as network nodes that influence each other. The directional influence from one region to another is referred to as directional connectivity. Epilepsy is a…

Applications · Statistics 2022-08-18 Yaotian Wang , Guofen Yan , Seiji Tanabe , Chang-Chia Liu , Shayan Moosa , Mark S. Quigg , Tingting Zhang

Whole-brain models offer a promising method of predicting seizure spread, which is critical for successful surgery treatment of focal epilepsy. Existing methods are largely based on structural connectome, which ignores the effects of…

Neurons and Cognition · Quantitative Biology 2022-07-13 Chen Wang , Sida Chen , Liang Huang , Lianchun Yu

Improving the controllability of power networks is crucial as they are highly complex networks operating in synchrony; even minor perturbations can cause desynchronization and instability. To that end, one needs to assess the criticality of…

Systems and Control · Electrical Eng. & Systems 2025-05-16 MirSaleh Bahavarnia , Muhammad Nadeem , Ahmad F. Taha

In recent years, machine learning has become an increasingly powerful tool for supporting seizure detection and monitoring in epilepsy care. Traditional approaches focus on identifying seizures only after they begin, which limits the…

Machine Learning · Computer Science 2025-10-30 Ria Jayanti , Tanish Jain

Therapeutic intervention in neurological disorders still relies heavily on pharmacological solutions, while the treatment of patients with drug resistance remains an open challenge. This is particularly true for patients with epilepsy, 30%…

Human-Computer Interaction · Computer Science 2022-10-20 Margherita Ronchini , Yasser Rezaeiyan , Milad Zamani , Gabriella Panuccio , Farshad Moradi

This study investigated the dynamic connectivity patterns between EEG and fMRI modalities, contributing to our understanding of brain network interactions. By employing a comprehensive approach that integrated static and dynamic analyses of…

Machine Learning · Computer Science 2024-12-02 Guiran Liu , Binrong Zhu

Epilepsy is one of the most common neurological disorders, typically observed via seizure episodes. Epileptic seizures are commonly monitored through electroencephalogram (EEG) recordings due to their routine and low expense collection. The…

Signal Processing · Electrical Eng. & Systems 2023-01-10 İlkay Yıldız Potter , George Zerveas , Carsten Eickhoff , Dominique Duncan

Periodic pulse train stimulation is generically used to study the function of the nervous system and to counteract disease-related neuronal activity, e.g., collective periodic neuronal oscillations. The efficient control of neuronal…

Adaptation and Self-Organizing Systems · Physics 2020-08-05 Kestutis Pyragas , Augustinas P. Fedaravičius , Tatjana Pyragienė

Epilepsy can be treated with medication, however, $30\%$ of epileptic patients are still drug resistive. Devices like responsive neurostimluation systems are implanted in select patients who may not be amenable to surgical resection.…

The psychosis spectrum is associated with structural dysconnectivity concentrated in transmodal association cortex. However, understanding of this pathophysiology has been limited by an exclusive focus on the direct connections to a region.…