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Epilepsy is the most common, chronic, neurological disease worldwide and is typically accompanied by reoccurring seizures. Neuro implants can be used for effective treatment by suppressing an upcoming seizure upon detection. Due to the…

Signal Processing · Electrical Eng. & Systems 2025-05-12 Julia Werner , Bhavya Kohli , Paul Palomero Bernardo , Christoph Gerum , Oliver Bringmann

Epilepsy is a neurological illness that is characterised by continuous spasms of shaking, sometimes known as convulsions. Although there are effective treatments for epilepsy, such as drugs and surgery, there is still a group of individuals…

Artificial Intelligence · Computer Science 2023-05-01 Ishan Shivansh Bangroo , Samia Tahzeen

Understanding brain dynamics in epilepsy is critical for establishing rigorous control objectives that enable new therapeutic methods to mitigate seizure occurrence. In multichannel electrocorticography (ECoG) recordings acquired in 21…

Excessively high, neural synchronisation has been associated with epileptic seizures, one of the most common brain diseases worldwide. A better understanding of neural synchronisation mechanisms can thus help control or even treat epilepsy.…

Drug-resistant epilepsy is traditionally characterized by pathologic cortical tissue comprised of seizure-initiating `foci'. These `foci' are thought to be embedded within an epileptic network whose functional architecture dynamically…

Neurons and Cognition · Quantitative Biology 2016-02-17 Ankit Khambhati , Brian Litt , Danielle S. Bassett

Medically uncontrolled epileptic seizures affect nearly 15 million people worldwide, resulting in enormous economic and psychological burdens. Treatment of medically refractory epilepsy is essential for patients to achieve remission,…

Quantitative Methods · Quantitative Biology 2025-12-25 Yaoyue Wang , Arian Ashourvan , Guilherme Ramos , Paul Bogdan , Emily Pereira

Epilepsy is a chronic, noncommunicable brain disorder, and sudden seizure onsets can significantly impact patients' quality of life and health. However, wearable seizure-predicting devices are still limited, partly due to the bulky size of…

Signal Processing · Electrical Eng. & Systems 2025-07-22 Ruifeng Zheng , Cong Chen , Shuang Wang , Yiming Liu , Lin You , Jindong Lu , Ruizhe Zhu , Guodao Zhang , Kejie Huang

Epileptic seizure prediction from electroencephalographic (EEG) recordings remains challenging due to strong inter-patient variability and the complex temporal structure of neural signals. This paper presents a patient-adaptive transformer…

Machine Learning · Computer Science 2026-03-31 Mohamed Mahdi , Asma Baghdadi

Epileptic seizures are characterized by abnormal and excessive neural activity, where cortical network dynamics seem to become unstable. However, most of the time, during seizure-free periods, cortex of epilepsy patients shows perfectly…

Neurons and Cognition · Quantitative Biology 2021-04-06 Annika Hagemann , Jens Wilting , Bita Samimizad , Florian Mormann , Viola Priesemann

Recent advances in control theory yield closed-loop neurostimulations for suppressing epileptiform seizures. These advances are illustrated by computer experiments which are easy to implement and to tune. The feedback synthesis is provided…

Systems and Control · Electrical Eng. & Systems 2024-10-03 Cédric Join , D. Blair Jovellar , Emmanuel Delaleau , Michel Fliess

Epileptic seizures detection and forecasting is nowadays widely recognized as a problem of great significance and social resonance, and still remains an open, grand challenge. Furthermore, the development of mobile warning systems and…

Quantitative Methods · Quantitative Biology 2018-12-10 Roberto Zingone , Chiara Mocenni , Dario Madeo

Objective: Epilepsy, a prevalent neurological disease, demands careful diagnosis and continuous care. Seizure detection remains challenging, as current clinical practice relies on expert analysis of electroencephalography, which is a…

Machine Learning · Computer Science 2025-09-18 Amirhossein Shahbazinia , Jonathan Dan , Jose A. Miranda , Giovanni Ansaloni , David Atienza

Epilepsy is one of the most prevalent neurological conditions, where an epileptic seizure is a transient occurrence due to abnormal, excessive and synchronous activity in the brain. Electroencephalogram signals emanating from the brain may…

Neurons and Cognition · Quantitative Biology 2023-12-05 Paul Grant , Md Zahidul Islam

Epilepsy is a neurological disorder arising from anomalies of the electrical activity in the brain, affecting about 0.5--0.8\% of the world population. Several studies investigated the relationship between seizures and brainwave…

Machine Learning · Computer Science 2018-01-25 Paolo Detti , Garazi Zabalo Manrique de Lara , Renato Bruni , Marco Pranzo , Francesco Sarnari

We consider an excitatory random network of leaky integrate-and-fire pulse coupled neurons. The neurons are connected as in a directed Erd\"os-Renyi graph with average connectivity $<k>$ scaling as a power law with the number of neurons in…

Disordered Systems and Neural Networks · Physics 2012-08-28 Lorenzo Tattini , Simona Olmi , Alessandro Torcini

Predicting post-operative seizure freedom using functional correlation networks derived from interictal intracranial EEG has shown some success. However, there are important challenges to consider. 1: electrodes physically closer to each…

Neurostimulation is a promising therapy for abating epileptic seizures. However, it is extremely difficult to identify optimal stimulation patterns experimentally. In this study human recordings are used to develop a functional 24 neuron…

Epilepsy is one of the most occurring neurological diseases. The main characteristic of this disease is a frequent seizure, which is an electrical imbalance in the brain. It is generally accompanied by shaking of body parts and even leads…

Machine Learning · Computer Science 2023-03-22 Shivam Gupta , Virender Ranga , Priyansh Agrawal

Epileptic seizures arise from abnormally synchronised neural activity and remain a major global health challenge, affecting more than 50 million people worldwide. Despite advances in pharmacological interventions, a significant proportion…

Signal Processing · Electrical Eng. & Systems 2025-12-19 Arfan Ghani

Critical dynamics are assumed to be an attractive mode for normal brain functioning as information processing and computational capabilities are found to be optimized there. Recent experimental observations of neuronal activity patterns…

Neurons and Cognition · Quantitative Biology 2015-05-28 Christian Meisel , Alexander Storch , Susanne Hallmeyer-Elgner , Ed Bullmore , Thilo Gross