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This paper proposes a novel topological learning framework that integrates networks of different sizes and topology through persistent homology. Such challenging task is made possible through the introduction of a computationally efficient…

Neurons and Cognition · Quantitative Biology 2023-01-30 Tananun Songdechakraiwut , Moo K. Chung

This thesis is a compendium of research which brings together ideas from the fields of Complex Networks and Computational Neuroscience to address two questions regarding neural systems: 1) How the activity of neurons, via synaptic changes,…

Neurons and Cognition · Quantitative Biology 2013-02-19 Samuel Johnson

Network topology inference is a fundamental problem in many applications of network science, such as locating the source of fake news, brain connectivity networks detection, etc. Many real-world situations suffer from a critical problem…

Applications · Statistics 2022-06-22 Yupeng Chen , Zhiguo Wang , Xiaojing Shen

Regulatory networks describe the interactions between molecular or cellular regulators, like transcription factors and genes in gene regulatory networks, kinases and their receptors in signalling networks, or neurons in neural networks. A…

Molecular Networks · Quantitative Biology 2022-12-29 Niklas Bonacker , Johannes Berg

In this paper, we consider the problem of optimal exogenous control of gene regulatory networks. Our approach consists in adapting an established reinforcement learning algorithm called the fitted Q iteration. This algorithm infers the…

Systems and Control · Computer Science 2015-02-26 Aivar Sootla , Natalja Strelkowa , Damien Ernst , Mauricio Barahona , Guy-Bart Stan

The inverse statistical problem of finding direct interactions in complex networks is difficult. In the natural sciences, well-controlled perturbation experiments are widely used to probe the structure of complex networks. However, our…

Disordered Systems and Neural Networks · Physics 2019-10-24 Jialong Jiang , David A. Sivak , Matt Thomson

We explore the problem of inferring the graph Laplacian of a weighted, undirected network from snapshots of a single or multiple discrete-time consensus dynamics, subject to parameter uncertainty, taking place on the network. Specifically,…

Social and Information Networks · Computer Science 2020-05-08 Yu Zhu , Michael T. Schaub , Ali Jadbabaie , Santiago Segarra

The characterisation of neuronal connectivity is one of the most important matters in neuroscience. In this work, we show that a recently proposed informational quantity, the causal mutual information, employed with an appropriate…

Neurons and Cognition · Quantitative Biology 2018-02-14 F. S. Borges , E. L. Lameu , K. C. Iarosz , P. R. Protachevicz , I. L. Caldas , R. L. Viana , E. E. N. Macau , A. M. Batista , M. S. Baptista

We consider fair network topology inference from nodal observations. Real-world networks often exhibit biased connections based on sensitive nodal attributes. Hence, different subpopulations of nodes may not share or receive information…

Signal Processing · Electrical Eng. & Systems 2024-03-26 Madeline Navarro , Samuel Rey , Andrei Buciulea , Antonio G. Marques , Santiago Segarra

Network topology inference is a cornerstone problem in statistical analyses of complex systems. In this context, the fresh look advocated here permeates benefits from convex optimization and graph signal processing, to identify the…

Social and Information Networks · Computer Science 2016-04-12 Santiago Segarra , Antonio G. Marques , Gonzalo Mateos , Alejandro Ribeiro

The relationship between complex, brain oscillations and the dynamics of individual neurons is poorly understood. Here we utilize Maximum Caliber, a dynamical inference principle, to build a minimal, yet general model of the collective…

Neurons and Cognition · Quantitative Biology 2020-09-04 Corey Weistuch , Lilianne R. Mujica-Parodi , Ken Dill

Recurrent neural networks have seen widespread use in modeling dynamical systems in varied domains such as weather prediction, text prediction and several others. Often one wishes to supplement the experimentally observed dynamics with…

Disordered Systems and Neural Networks · Physics 2022-12-14 Sun-Ting Tsai , Eric Fields , Yijia Xu , En-Jui Kuo , Pratyush Tiwary

The characterisation of quantum networks is fundamental to understanding how energy and information propagates through complex systems, with applications in control, communication, error mitigation and energy transfer. In this work, we…

Quantum Physics · Physics 2025-09-19 Conall J. Campbell , Matthew Mackinnon , Mauro Paternostro , Diana A. Chisholm

The inference of gene regulatory networks from high throughput gene expression data is one of the major challenges in systems biology. This paper aims at analysing and comparing two different algorithmic approaches. The first approach uses…

Quantitative Methods · Quantitative Biology 2008-12-05 A. Braunstein , A. Pagnani , M. Weigt , R. Zecchina

Network inference, the task of reconstructing interactions in a complex system from experimental observables, is a central yet extremely challenging problem in systems biology. While much progress has been made in the last two decades,…

Quantitative Methods · Quantitative Biology 2024-09-12 Stephen Y Zhang

We consider the problem of inferring the functional connectivity of a large-scale computer network from sparse time series of events emitted by its nodes. We do so under the following three domain-specific constraints: (a) non-stationarity…

Machine Learning · Computer Science 2018-02-13 Antoine Messager , George Parisis , Istvan Z Kiss , Robert Harper , Phil Tee , Luc Berthouze

Recent work has shown that probabilistic models based on pairwise interactions-in the simplest case, the Ising model-provide surprisingly accurate descriptions of experiments on real biological networks ranging from neurons to genes.…

Quantitative Methods · Quantitative Biology 2007-12-18 Tamara Broderick , Miroslav Dudik , Gasper Tkacik , Robert E. Schapire , William Bialek

We consider the problem of estimating the topology of multiple networks from nodal observations, where these networks are assumed to be drawn from the same (unknown) random graph model. We adopt a graphon as our random graph model, which is…

Machine Learning · Statistics 2022-12-21 Madeline Navarro , Santiago Segarra

With the recent success of deep neural networks in computer vision, it is important to understand the internal working of these networks. What does a given neuron represent? The concepts captured by a neuron may be hard to understand or…

Computer Vision and Pattern Recognition · Computer Science 2020-12-29 Suryabhan Singh Hada , Miguel Á. Carreira-Perpiñán

The dynamics of neural networks is often characterized by collective behavior and quasi-synchronous events, where a large fraction of neurons fire in short time intervals, separated by uncorrelated firing activity. These global temporal…

Disordered Systems and Neural Networks · Physics 2014-10-03 Raffaella Burioni , Mario Casartelli , Matteo di Volo , Roberto Livi , Alessandro Vezzani