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One of the paramount challenges in neuroscience is to understand the dynamics of individual neurons and how they give rise to network dynamics when interconnected. Historically, researchers have resorted to graph theory, statistics, and…

Neurons and Cognition · Quantitative Biology 2019-02-08 Jean-Baptiste Bardin , Gard Spreemann , Kathryn Hess

Biomolecular networks have already found great utility in characterizing complex biological systems arising from pair-wise interactions amongst biomolecules. Here, we review how graph theoretical approaches can be applied not only for a…

Molecular Networks · Quantitative Biology 2018-12-03 Heeralal Janwa , Steven E. Massey , Julian Velev , Bud Mishra

Over the past years, embedding learning on networks has shown tremendous results in link prediction tasks for complex systems, with a wide range of real-life applications. Learning a representation for each node in a knowledge graph allows…

Machine Learning · Computer Science 2026-02-03 Orell Trautmann , Olaf Wolkenhauer , Clémence Réda

We consider network topology identification subject to a signal smoothness prior on the nodal observations. A fast dual-based proximal gradient algorithm is developed to efficiently tackle a strongly convex, smoothness-regularized network…

Machine Learning · Computer Science 2021-10-20 Seyed Saman Saboksayr , Gonzalo Mateos

By studying varies dynamical processes, including coupled maps, cellular automata and coupled differential equations, on five different kinds of known networks, we found a positive relation between signal correlation and node's degree. Thus…

Statistical Mechanics · Physics 2007-05-23 Lei Yang , Liang Huang , Yong Zhang , Kongqing Yang

Boolean networks have been proposed as potentially useful models for genetic control. An important aspect of these networks is the stability of their dynamics in response to small perturbations. Previous approaches to stability have assumed…

Molecular Networks · Quantitative Biology 2015-05-13 Andrew Pomerance , Edward Ott , Michelle Girvan , Wolfgang Losert

We propose and analyze a graph model to study the connectivity of interdependent networks. Two interdependent networks of arbitrary topologies are modeled as two graphs, where every node in one graph is supported by supply nodes in the…

Discrete Mathematics · Computer Science 2018-09-10 Jianan Zhang , Eytan Modiano

Much recent research has dealt with the identifiability of a dynamical network in which the node signals are connected by causal linear transfer functions and are excited by known external excitation signals and/or unknown noise signals. A…

Optimization and Control · Mathematics 2018-03-18 Julien M. Hendrickx , Michel Gevers , Alexandre S. Bazanella

Sometimes it is not enough for a DNN to produce an outcome. For example, in applications such as healthcare, users need to understand the rationale of the decisions. Therefore, it is imperative to develop algorithms to learn models with…

Machine Learning · Computer Science 2019-01-29 Yinpeng Dong , Fan Bao , Hang Su , Jun Zhu

We present a brief introduction to a flexible, general network inference framework which models data as a network space, sampled to optimize network structure to a particular task. We introduce a formal problem statement related to…

Social and Information Networks · Computer Science 2017-05-03 Ivan Brugere , Chris Kanich , Tanya Y. Berger-Wolf

Network inference is the process of learning the properties of complex networks from data. Besides using information about known links in the network, node attributes and other forms of network metadata can help to solve network inference…

Data Analysis, Statistics and Probability · Physics 2021-03-29 Oscar Fajardo-Fontiveros , Marta Sales-Pardo , Roger Guimera

Cell signaling networks are complex and often incompletely characterized, making it difficult to obtain a comprehensive picture of the mechanisms they encode. Mathematical modeling of these networks provides important clues, but the models…

Molecular Networks · Quantitative Biology 2022-11-07 Soutick Saha , Hye-ran Moon , Bumsoo Han , Andrew Mugler

We consider the following learning problem: Given sample pairs of input and output signals generated by an unknown nonlinear system (which is not assumed to be causal or time-invariant), we wish to find a continuous-time recurrent neural…

Machine Learning · Computer Science 2021-11-18 Joshua Hanson , Maxim Raginsky , Eduardo Sontag

The network inference problem consists of reconstructing the edge set of a network given traces representing the chronology of infection times as epidemics spread through the network. This problem is a paradigmatic representative of…

Data Structures and Algorithms · Computer Science 2013-08-14 Bruno Abrahao , Flavio Chierichetti , Robert Kleinberg , Alessandro Panconesi

Graph signals are functions of the underlying graph. When the edge-weight between a pair of nodes is high, the corresponding signals generally have a higher correlation. As a result, the signals can be represented in terms of a graph-based…

Signal Processing · Electrical Eng. & Systems 2024-09-09 Rishabh Ravi , Kaushani Majumder , Kalp Vyas , Satish Mulleti

An increasing number of applications require real-time reasoning under uncertainty with streaming input. The temporal (dynamic) Bayes net formalism provides a powerful representational framework for such applications. However, existing…

Artificial Intelligence · Computer Science 2013-01-07 Masami Takikawa , Bruce D'Ambrosio , Ed Wright

Optimal control of complex environments with robotic systems faces two complementary and intertwined challenges: efficient organization of sensory state information and far-sighted action planning. Because the reinforcement learning…

Machine Learning · Computer Science 2026-01-30 Abdullah Akgül , Gulcin Baykal , Manuel Haußmann , Mustafa Mert Çelikok , Melih Kandemir

Biological processes, including cell differentiation, organism development, and disease progression, can be interpreted as attractors (fixed points or limit cycles) of an underlying networked dynamical system. In this paper, we study the…

Systems and Control · Computer Science 2017-01-20 Andrew Clark , Phillip Lee , Basel Alomair , Linda Bushnell , Radha Poovendran

Several types of biological networks have recently been shown to be accurately described by a maximum entropy model with pairwise interactions, also known as the Ising model. Here we present an approach for finding the optimal mappings…

Biological Physics · Physics 2015-05-14 Jeffrey D. Fitzgerald , Tatyana O. Sharpee

Extracting useful information from data is a fundamental challenge across disciplines as diverse as climate, neuroscience, genetics, and ecology. In the era of ``big data'', data is ubiquitous, but appropriated methods are needed for…

Chaotic Dynamics · Physics 2018-12-26 Nicolas Rubido , Cristina Masoller
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