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Computational complexity is a key limitation of genomic analyses. Thus, over the last 30 years, researchers have proposed numerous fast heuristic methods that provide computational relief. Comparing genomic sequences is one of the most…

Machine learning has been gaining traction in recent years to meet the demand for tools that can efficiently analyze and make sense of the ever-growing databases of biomedical data in health care systems around the world. However,…

Neural and Evolutionary Computing · Computer Science 2017-02-08 Andrew Sohn , Randal S. Olson , Jason H. Moore

High throughput technologies have become the practice of choice for comparative studies in biomedical applications. Limited number of sample points due to sequencing cost or access to organisms of interest necessitates the development of…

Methodology · Statistics 2018-07-17 Ariana Broumand , Siamak Zamani Dadaneh

Genetic Algorithms (GAs) are used to solve search and optimization problems in which an optimal solution can be found using an iterative process with probabilistic and non-deterministic transitions. However, depending on the problem's…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-23 Matheus F. Torquato , Marcelo A. C. Fernandes

The rise of big data systems has created a need for benchmarks to measure and compare the capabilities of these systems. Big data benchmarks present unique scalability challenges. The supercomputing community has wrestled with these…

Performance · Computer Science 2016-12-13 Patrick Dreher , Chansup Byun , Chris Hill , Vijay Gadepally , Bradley Kuszmaul , Jeremy Kepner

Existing GPU-sharing techniques, including spatial and temporal sharing, aim to improve utilization but face challenges in simultaneously ensuring SLO adherence and maximizing efficiency due to the lack of fine-grained task scheduling on…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-11 Tiancheng Hu , Chenxi Wang , Ting Cao , Jin Qin , Lei Chen , Xinyu Xiao , Junhao Hu , Hongliang Tian , Shoumeng Yan , Huimin Cui , Quan Chen , Tao Xie

Model parallelism has become a necessity for training modern large-scale deep language models. In this work, we identify a new and orthogonal dimension from existing model parallel approaches: it is possible to perform pipeline parallelism…

Machine Learning · Computer Science 2021-09-29 Zhuohan Li , Siyuan Zhuang , Shiyuan Guo , Danyang Zhuo , Hao Zhang , Dawn Song , Ion Stoica

A parallel code has been written in FORTRAN90, C, and MPI for the analysis of biological simulation data. Using a master/slave algorithm, the software operates on AMBER generated trajectory data using either UNIX or MPI file IO, and it…

Computational Physics · Physics 2008-08-25 David N. Lebard

Genome sequencing is essential to decode genetic information, identify organisms, understand diseases and advance personalized medicine. A critical step in any genome sequencing technique is genome assembly. However, de novo genome…

Particle track reconstruction is traditionally computationally challenging due to the combinatorial nature of the tracking algorithms employed. Recent developments have focused on novel algorithms with graph neural networks (GNNs), which…

Data Analysis, Statistics and Probability · Physics 2025-06-05 Jay Chan , Brandon Wang , Paolo Calafiura

Retrieval-augmented generation (RAG) has emerged as a promising paradigm for improving factual accuracy in large language models (LLMs). We introduce a benchmark designed to evaluate RAG pipelines as a whole, evaluating a pipeline's ability…

Artificial Intelligence · Computer Science 2026-05-25 Samuel Hildebrand , Curtis Taylor , Sean Oesch , James M Ghawaly , Amir Sadovnik , Ryan Shivers , Brandon Schreiber , Kevin Kurian

Cancer survival prediction is an active area of research that can help prevent unnecessary therapies and improve patient's quality of life. Gene expression profiling is being widely used in cancer studies to discover informative biomarkers…

Machine Learning · Computer Science 2016-11-18 Hamid Reza Hassanzadeh , John H. Phan , May D. Wang

Vibration analysis is an active area of research, aimed, among other targets, at an accurate classification of machinery failure modes. This often leads to complex and convoluted signal processing pipeline designs, which are computationally…

Signal Processing · Electrical Eng. & Systems 2021-10-29 Artur Sokolovsky , David Hare , Jorn Mehnen

High throughput and low latency data processing is essential for systems requiring live decision making, control, and machine learning-optimized data reduction. We focus on two distinct use cases for in-flight streaming data processing for…

Instrumentation and Detectors · Physics 2023-02-14 Jack Hirschman , Andrei Kamalov , Razib Obaid , Finn H. O'Shea , Ryan N Coffee

In this paper GA based light weight faster version of Digital Signature Algorithm (GADSA) in wireless communication has been proposed. Various genetic operators like crossover and mutation are used to optimizing amount of modular…

Cryptography and Security · Computer Science 2012-08-14 Arindam Sarkar , J. K. Mandal

High-dimensional time series phenotypic data is becoming increasingly common within plant breeding programmes. However, analysing and integrating such data for genetic analysis and genomic prediction remains difficult. Here we show how…

We propose, implement, and experimentally evaluate a runtime middleware to support high-throughput execution on hybrid cluster machines of large-scale analysis applications. A hybrid cluster machine consists of computation nodes which have…

Distributed, Parallel, and Cluster Computing · Computer Science 2012-09-18 George Teodoro , Tony Pan , Tahsin M. Kurc , Jun Kong , Lee A. D. Cooper , Joel H. Saltz

In this work, we propose a new approach towards the efficient optimization and implementation of reservoir computing hardware reducing the required domain expert knowledge and optimization effort. First, we adapt the reservoir input mask to…

Emerging Technologies · Computer Science 2018-10-31 Bogdan Penkovsky , Laurent Larger , Daniel Brunner

The ever-increasing size and computational complexity of today's machine-learning algorithms pose an increasing strain on the underlying hardware. In this light, novel and dedicated architectural solutions are required to optimize energy…

Hardware Architecture · Computer Science 2022-12-20 Pengbo Yu , Alexandre Levisse , Mohit Gupta , Evenblij Timon , Giovanni Ansaloni , Francky Catthoor , David Atienza

Transformers-based models, such as BERT, have been one of the most successful deep learning models for NLP. Unfortunately, one of their core limitations is the quadratic dependency (mainly in terms of memory) on the sequence length due to…