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Background: With the rapid growth of massively parallel sequencing technologies, still more laboratories are utilizing sequenced DNA fragments for genomic analyses. Interpretation of sequencing data is, however, strongly dependent on…

The effectiveness of the machine learning methods for real-world tasks depends on the proper structure of the modeling pipeline. The proposed approach is aimed to automate the design of composite machine learning pipelines, which is…

Quantum signal processing provides an optimal procedure for simulating Hamiltonian evolution on a quantum computer using calls to a block encoding of the Hamiltonian. In many situations it is possible to control between forward and reverse…

Quantum Physics · Physics 2024-07-17 Dominic W. Berry , Danial Motlagh , Giacomo Pantaleoni , Nathan Wiebe

Genomic signal processing has been used successfully in bioinformatics to analyze biomolecular sequences and gain varied insights into DNA structure, gene organization, protein binding, sequence evolution, etc. But challenges remain in…

Genomics · Quantitative Biology 2022-11-04 Saish Jaiswal , Shreya Nema , Hema A Murthy , Manikandan Narayanan

Quantum processors require rapid and high-fidelity simultaneous measurements of many qubits. While superconducting qubits are among the leading modalities toward a useful quantum processor, their readout remains a bottleneck. Traditional…

Quantum Physics · Physics 2026-04-08 Robert Kent , Benjamin Lienhard , Gregory Lafyatis , Daniel J. Gauthier

Applications of machine learning and graph theory techniques to neuroscience have witnessed an increased interest in the last decade due to the large data availability and unprecedented technology developments. Their employment to…

The ability to quickly and accurately identify microbial species in a sample, known as metagenomic profiling, is critical across various fields, from healthcare to environmental science. This paper introduces a novel method to profile…

Genomics · Quantitative Biology 2025-04-10 Riselda Kodra , Hadjer Benmeziane , Irem Boybat , William Andrew Simon

Retrieval-augmented generation (RAG) mitigates hallucination in Large Language Models (LLMs) by using query pipelines to retrieve relevant external information and grounding responses in retrieved knowledge. However, query pipeline…

Computation and Language · Computer Science 2026-04-17 Maolin He , Rena Gao , Mike Conway , Brian E. Chapman

In this work, we examine the problem of efficiently preprocessing high volume bird acoustic data. We combine several existing preprocessing steps including noise reduction approaches into a single efficient pipeline by examining each…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-02-05 Alexander Brown , Saurabh Garg , James Montgomery

We present a novel methodology for exploring local features directly in the primordial power spectrum using a genetic algorithm (GA) pipeline coupled with a Boltzmann solver and Cosmic Microwave Background data (CMB). After testing the…

Cosmology and Nongalactic Astrophysics · Physics 2024-06-04 Kushal Lodha , Lucas Pinol , Savvas Nesseris , Arman Shafieloo , Wuhyun Sohn , Matteo Fasiello

The devices designed for the Internet-of-Things encompass a large variety of distinct processor architectures, forming a highly heterogeneous zoo. In order to tackle this, we employ a simulator to estimate the performance of the…

Hardware Architecture · Computer Science 2024-03-13 Cristian Ramírez , Adrián Castelló , Héctor Martínez , Enrique S. Quintana-Ortí

The most general searches for gravitational wave transients (GWTs) rely on data analysis methods that do not assume prior knowledge of the signal waveform, direction, or arrival time on Earth. These searches provide data-driven signal…

In recent years the publication of genome sequences for the Chinese hamster and Chinese hamster ovary (CHO) cell lines have facilitated study of these biopharmaceutical cell factories with unprecedented resolution. Our understanding of the…

Genomics · Quantitative Biology 2019-05-02 Craig Monger , Krishna Motheramgari , John McSharry , Niall Barron , Colin Clarke

Biosciences have been revolutionized by next generation sequencing (NGS) technologies in last years, leading to new perspectives in medical, industrial and environmental applications. And although our motivation comes from biosciences, the…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-01-16 Bruno Dantas , Calmenelias Fleitas , Alexandre P. Francisco , José Simão , Cátia Vaz

Next Generation Sequencing (NGS), a recently evolved technology, have served a lot in the research and development sector of our society. This novel approach is a newbie and has critical advantages over the traditional Capillary…

Genomics · Quantitative Biology 2020-05-01 Khalid Raza , Sabahuddin Ahmad

Machine Learning (ML) adoption in the enterprise requires simpler and more efficient software infrastructure---the bespoke solutions typical in large web companies are simply untenable. Model scoring, the process of obtaining predictions…

Machine Learning · Computer Science 2020-10-20 Supun Nakandala , Karla Saur , Gyeong-In Yu , Konstantinos Karanasos , Carlo Curino , Markus Weimer , Matteo Interlandi

The training of Transformer models has revolutionized natural language processing and computer vision, but it remains a resource-intensive and time-consuming process. This paper investigates the applicability of the early-bird ticket…

Computation and Language · Computer Science 2024-05-07 Shravan Cheekati

The third-generation long reads sequencing technologies, such as PacBio and Nanopore, have great advantages over second-generation Illumina sequencing in de novo assembly studies. However, due to the inherent low base accuracy,…

Genomics · Quantitative Biology 2020-03-27 Hengchao Wang , Bo Liu , Yan Zhang , Fan Jiang , Yuwei Ren , Lijuan Yin , Hangwei Liu , Sen Wang , Wei Fan

Reducing a set of numbers to a single value is a fundamental operation in applications such as signal processing, data compression, scientific computing, and neural networks. Accumulation, which involves summing a dataset to obtain a single…

Hardware Architecture · Computer Science 2025-09-22 Ahmad Houraniah , H. Fatih Ugurdag , Furkan Aydin