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Profile likelihood provides a general framework to infer on a scalar parameter of a statistical model. A confidence interval is obtained by numerically finding the two abscissas where the profile log-likelihood curve intersects an…

Computation · Statistics 2024-04-04 Yves Deville

We study the frequentist properties of confidence intervals computed by the method known to statisticians as the Profile Likelihood. It is seen that the coverage of these intervals is surprisingly good over a wide range of possible…

Data Analysis, Statistics and Probability · Physics 2009-11-10 Wolfgang A. Rolke , Angel M. Lopez , Jan Conrad

In this paper, we propose and analyze a trust-region model-based algorithm for solving unconstrained stochastic optimization problems. Our framework utilizes random models of an objective function $f(x)$, obtained from stochastic…

Optimization and Control · Mathematics 2016-09-26 Ruobing Chen , Matt Menickelly , Katya Scheinberg

In this paper, we develop efficient randomized algorithms for estimating probabilistic robustness margin and constructing robustness degradation curve for uncertain dynamic systems. One remarkable feature of these algorithms is their…

Optimization and Control · Mathematics 2008-05-13 Xinjia Chen , Kemin Zhou , Jorge L. Aravena

Autoregressive moving average (ARMA) models are widely used for analyzing time series data. However, standard likelihood-based inference methodology for ARMA models has avoidable limitations. We show that currently accepted standards for…

Methodology · Statistics 2025-10-28 Jesse Wheeler , Edward L. Ionides

Symbolic regression is a nonlinear regression method which is commonly performed by an evolutionary computation method such as genetic programming. Quantification of uncertainty of regression models is important for the interpretation of…

Machine Learning · Computer Science 2022-09-15 Fabricio Olivetti de Franca , Gabriel Kronberger

This paper introduces a first implementation of a novel likelihood-ratio-based approach for constructing confidence intervals for neural networks. Our method, called DeepLR, offers several qualitative advantages: most notably, the ability…

Machine Learning · Statistics 2023-08-07 Laurens Sluijterman , Eric Cator , Tom Heskes

Likelihood-free Bayesian inference algorithms are popular methods for calibrating the parameters of complex, stochastic models, required when the likelihood of the observed data is intractable. These algorithms characteristically rely…

Computation · Statistics 2021-12-23 Thomas P Prescott , David J Warne , Ruth E Baker

Mechanistic dynamic models of biochemical networks such as Ordinary Differential Equations (ODEs) contain unknown parameters like the reaction rate constants and the initial concentrations of the compounds. The large number of parameters as…

Data Analysis, Statistics and Probability · Physics 2017-08-14 Clemens Kreutz , Andreas Raue , Jens Timmer

We consider the problem of inferring constraints on a high-dimensional parameter space with a computationally expensive likelihood function. We propose a machine learning algorithm that maps out the Frequentist confidence limit on parameter…

Cosmology and Nongalactic Astrophysics · Physics 2014-09-25 Scott F. Daniel , Andrew J. Connolly , Jeff Schneider

The asymptotic results pertaining to the distribution of the log likelihood ratio allow for the creation of a confidence region, which is a general extension of the confidence interval. Two and three dimensional regions can be displayed…

Methodology · Statistics 2017-03-08 Adam Jaeger

Confidence intervals are a standard technique for analyzing data. When applied to time series, confidence intervals are computed for each time point separately. Alternatively, we can compute confidence bands, where we are required to find…

Machine Learning · Computer Science 2021-12-14 Nikolaj Tatti

We propose simple formulas of confidence intervals for the Wald statistic, likelihood ratio statistic, and score statistic for a network meta-analysis. In addition, we consider resolutions for concerns that network meta-analyses with a…

Methodology · Statistics 2022-01-12 Masahiro Kojima

Monte Carlo methods to evaluate and maximize the likelihood function enable the construction of confidence intervals and hypothesis tests, facilitating scientific investigation using models for which the likelihood function is intractable.…

Methodology · Statistics 2017-02-13 Edward L. Ionides , Carles Breto , Joonha Park , Richard A. Smith , Aaron A. King

In this paper we provide a new efficient algorithm for approximately computing the profile maximum likelihood (PML) distribution, a prominent quantity in symmetric property estimation. We provide an algorithm which matches the previous best…

Data Structures and Algorithms · Computer Science 2020-11-06 Nima Anari , Moses Charikar , Kirankumar Shiragur , Aaron Sidford

Intuitively, unfamiliarity should lead to lack of confidence. In reality, current algorithms often make highly confident yet wrong predictions when faced with relevant but unfamiliar examples. A classifier we trained to recognize gender is…

Computer Vision and Pattern Recognition · Computer Science 2020-09-09 Zhizhong Li , Derek Hoiem

A profile likelihood ratio test is proposed for inferences on the index coefficients in generalized single-index models. Key features include its simplicity in implementation, invariance against parametrization, and exhibiting substantially…

Methodology · Statistics 2017-06-27 Nanxi Zhang , Alan Huang

We study the problem of estimating finite sample confidence intervals of the mean of a normal population under the constraint of differential privacy. We consider both the known and unknown variance cases and construct differentially…

Cryptography and Security · Computer Science 2017-11-13 Vishesh Karwa , Salil Vadhan

We study an optimization-based approach to construct statistically accurate confidence intervals for simulation performance measures under nonparametric input uncertainty. This approach computes confidence bounds from simulation runs driven…

Methodology · Statistics 2019-02-14 Henry Lam , Huajie Qian

Some statistical models are specified via a data generating process for which the likelihood function cannot be computed in closed form. Standard likelihood-based inference is then not feasible but the model parameters can be inferred by…

Computation · Statistics 2015-02-20 Michael U. Gutmann , Jukka Corander , Ritabrata Dutta , Samuel Kaski
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