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Optical coherence tomography is state-of-the-art in non-invasive imaging of biological structures. Spectral Domain Optical Co-herence Tomography is the popularly used variation of this technique, but its performance is limited by the…

Optics · Physics 2023-03-01 Prabhav Gaur , Andrew Grieco , Yeshaiahu Fainman

We demonstrate an optical frequency analysis method using the Fourier transform of detection times of fluorescence photons emitted from a single trapped 40Ca+ ion. The response of the detected photon rate to the relative laser frequency…

Non-destructive testing (NDT) is crucial for ensuring product quality and safety across various industries. Conventional methods such as ultrasonic, terahertz, and X-ray imaging have limitations in terms of probe-contact requirement, depth…

Quantitative tissue information, like the light scattering properties, is considered as a key player in the detection of cancerous cells in medical diagnosis. A promising method to obtain these data is optical coherence tomography (OCT). In…

Numerical Analysis · Mathematics 2023-06-21 Leopold Veselka , Peter Elbau , Leonidas Mindrinos , Lisa Krainz , Wolfgang Drexler

Since their inception, superconducting nanowire single-photon detectors have been enabling quantum optical applications and the rise of the photonic quantum industry. The evolution in the detector design and read-out strategies has led to…

Quantum Physics · Physics 2024-12-19 Lorenzo Stasi , Towsif Taher , Giovanni V. Resta , Hugo Zbinden , Rob Thew , Félix Bussières

We implement a photon-counting Optical Time Domain Reflectometer (OTDR) at 1.55um which exhibits a high 2-point resolution and a high accuracy. It is based on a low temporal-jitter photon-counting module at 1.55um. This detector is composed…

Quantum Physics · Physics 2009-11-13 Matthieu Legre , Rob Thew , Hugo Zbinden , Nicolas Gisin

To recognize sub-micron range low energy tracks recorded in a super fine grained nuclear emulsion (Nano Imaging Tracker), an elliptical fitting method was devised to analyze anisotropic images taken by an optical microscope. In this paper,…

Instrumentation and Detectors · Physics 2020-03-31 Atsuhiro Umemoto , Tatsuhiro Naka , Toshiyuki Nakano , Ryuta Kobayashi , Takuya Shiraishi , Takashi Asada

Optical diffraction tomography (ODT) is a powerful non-invasive 3D imaging technique, but its combination with broadband light sources is difficult. In this study, we introduce ultrabroadband ODT, covering over 150 nm of visible spectral…

A recent advance in optical coherence tomography (OCT), termed swept-source OCT, is generalized into a new technique, Fourier-domain OCT. It represents a realization of a full-field OCT system in place of the conventional serial image…

Quantitative phase imaging (QPI) is often used for label-free single cell analysis with its high-contrast images of optical phase delay (OPD) map. Contrary to other imaging methods, sensitivity improvement has not been intensively explored…

Optics · Physics 2025-05-06 Keiichiro Toda , Miu Tamamitsu , Takuro Ideguchi

We apply three optical coherence tomography (OCT) image analysis techniques to extract morphometric information from OCT images obtained on peripheral nerves of rat. The accuracy of each technique is evaluated against histological…

Tissues and Organs · Quantitative Biology 2019-01-09 J. Hope , B. Brauer , S. Amirapu , A. McDaid , F. Vanholsbeeck

Quantum imaging exploits the spatial correlations between photons to image object features with a higher resolution than a corresponding classical light source could achieve. Using a quantum correlated $N$-photon state, the method of…

In this work, we propose to leverage a deep-learning (DL) based reconstruction framework for high quality Swept-Source Optical Coherence Tomography (SS-OCT) images, by incorporating wavelength ({\lambda}) space interferometric fringes.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Maryam Viqar , Erdem Sahin , Violeta Madjarova , Elena Stoykova , Keehoon Hong

The limits for adaptive-optics (AO) imaging at high contrast and high resolution are determined by residual phase errors from non-common-path aberrations not sensed by the wavefront sensor, especially for integral field spectrographs, where…

Instrumentation and Methods for Astrophysics · Physics 2015-06-22 Benjamin Pope , Niranjan Thatte , Rick Burruss , Matthias Tecza , Fraser Clarke , Garret Cotter

Efficiently distinguishing photon numbers is a crucial yet challenging technology for various quantum information and quantum metrology applications. While superconducting transition edge sensors offer good photon-number-resolving (PNR)…

In long adaptive optics corrected exposures, exoplanet detections are currently limited by speckle noise originating from the telescope and instrument optics, and it is expected that such noise will also limit future high-contrast imaging…

Astrophysics · Physics 2009-11-13 C. Marois , D. Lafreniere , B. Macintosh , R. Doyon

Optical photothermal microscopy is a powerful, emerging method that overcomes the diffraction limit in infrared hyperspectral imaging by utilizing a visible probe laser beam to detect local temperature-induced modulation at the visible…

In a recent publication we have proposed a numerical model that describes the detection process of optical photons in superconducting nanowire single-photon detectors (SNSPD). Here, we review this model and present a significant improvement…

Superconductivity · Physics 2015-06-24 Andreas Engel , Julia Lonsky , Xiaofu Zhang , Andreas Schilling

Optical coherence tomography (OCT) is commonly used to analyze retinal layers for assessment of ocular diseases. In this paper, we propose a method for retinal layer segmentation and quantification of uncertainty based on Bayesian deep…

Computer Vision and Pattern Recognition · Computer Science 2018-09-13 Suman Sedai , Bhavna Antony , Dwarikanath Mahapatra , Rahil Garnavi

Optical tomographic cross-sectional images of biological samples were made possible by interferometric imaging techniques such as Optical Coherence Tomography (OCT). Owing to its unprecedented view of the sample, OCT has become a gold…

Medical Physics · Physics 2020-07-13 Pedro Mecê , Elena Gofas-Salas , Michel Paques , Kate Grieve , Serge Meimon