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This paper studies a factor modeling-based approach for clustering high-dimensional data generated from a mixture of strongly correlated variables. Statistical modeling with correlated structures pervades modern applications in economics,…

Statistics Theory · Mathematics 2024-08-23 Shange Tang , Soham Jana , Jianqing Fan

Federated learning has attracted significant attention as a privacy-preserving framework for training personalised models on multi-source heterogeneous data. However, most existing approaches are unable to handle scenarios where subgroup…

Methodology · Statistics 2025-10-14 Changxin Yang , Zhongyi Zhu , Heng Lian

Accurate electroencephalogram (EEG) pattern decoding for specific mental tasks is one of the key steps for the development of brain-computer interface (BCI), which is quite challenging due to the considerably low signal-to-noise ratio of…

Signal Processing · Electrical Eng. & Systems 2020-12-15 Yu Zhang , Tao Zhou , Wei Wu , Hua Xie , Hongru Zhu , Guoxu Zhou , Andrzej Cichocki

Single-cell gene expression data are often characterized by large matrices, where the number of cells may be lower than the number of genes of interest. Factorization models have emerged as powerful tools to condense the available…

Methodology · Statistics 2023-05-22 Antonio Canale , Luisa Galtarossa , Davide Risso , Lorenzo Schiavon , Giovanni Toto

The task of clustering a set of objects based on multiple sources of data arises in several modern applications. We propose an integrative statistical model that permits a separate clustering of the objects for each data source. These…

Machine Learning · Statistics 2015-12-01 Eric F. Lock , David B. Dunson

With ongoing developments and innovations in single-cell RNA sequencing methods, advancements in sequencing performance could empower significant discoveries as well as new emerging possibilities to address biological and medical…

Applications · Statistics 2019-12-19 Jiawei Long , Yu Xia

The high dimensional nature of genomics data complicates feature selection, in particular in low sample size studies - not uncommon in clinical prediction settings. It is widely recognized that complementary data on the features, `co-data',…

Methodology · Statistics 2024-05-09 Mark A. van de Wiel , Wessel N. van Wieringen

A probabilistic clustering algorithm is proposed for the analysis of forensic DNA mixtures in which individual cells are isolated and short tandem repeats are amplified using the polymerase chain reaction to generate single cell…

Applications · Statistics 2025-10-14 Robert G. Cowell

In class-incremental learning, the model is expected to learn new classes continually while maintaining knowledge on previous classes. The challenge here lies in preserving the model's ability to effectively represent prior classes in the…

Computer Vision and Pattern Recognition · Computer Science 2022-08-17 Arjun Ashok , K J Joseph , Vineeth Balasubramanian

Microarrays are made it possible to simultaneously monitor the expression profiles of thousands of genes under various experimental conditions. Identification of co-expressed genes and coherent patterns is the central goal in microarray or…

Computational Engineering, Finance, and Science · Computer Science 2013-07-15 T. Chandrasekhar , K. Thangavel , E. Elayaraja , E. N. Sathishkumar

Unsupervised cell type identification is crucial for uncovering and characterizing heterogeneous populations in single cell omics studies. Although a range of clustering methods have been developed, most focus exclusively on intrinsic…

Artificial Intelligence · Computer Science 2025-12-12 Liang Peng , Haopeng Liu , Yixuan Ye , Cheng Liu , Wenjun Shen , Si Wu , Hau-San Wong

Recent works for attributed network clustering utilize graph convolution to obtain node embeddings and simultaneously perform clustering assignments on the embedding space. It is effective since graph convolution combines the structural and…

Machine Learning · Computer Science 2021-04-16 Shuiqiao Yang , Sunny Verma , Borui Cai , Jiaojiao Jiang , Kun Yu , Fang Chen , Shui Yu

Single-cell RNA sequencing (scRNA-seq) enables researchers to analyze gene expression at single-cell level. One important task in scRNA-seq data analysis is unsupervised clustering, which helps identify distinct cell types, laying down the…

Genomics · Quantitative Biology 2023-12-29 Weikang Jiang , Jinxian Wang , Jihong Guan , Shuigeng Zhou

Single-cell gene expression measurements encode variability spanning molecular noise, cell-to-cell heterogeneity, and technical artifacts. Mechanistic stochastic models provide powerful approaches to disentangle these sources, yet inferring…

Quantitative Methods · Quantitative Biology 2025-09-19 Christopher E. Miles

Deep clustering - joint representation learning and latent space clustering - is a well studied problem especially in computer vision and text processing under the deep learning framework. While the representation learning is generally…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Bishwajit Saha , Dmitry Krotov , Mohammed J. Zaki , Parikshit Ram

In semi-supervised domain adaptation, a few labeled samples per class in the target domain guide features of the remaining target samples to aggregate around them. However, the trained model cannot produce a highly discriminative feature…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Jichang Li , Guanbin Li , Yemin Shi , Yizhou Yu

We propose a new approach for clustering DNA features using array CGH data from multiple tumor samples. We distinguish data-collapsing: joining contiguous DNA clones or probes with extremely similar data into regions, from clustering:…

Applications · Statistics 2010-12-21 Kyung In Kim , Etienne Roquain , Mark Van De Wiel

Single-cell RNA sequencing (scRNA-seq) data analysis is pivotal for understanding cellular heterogeneity. However, the high sparsity and complex noise patterns inherent in scRNA-seq data present significant challenges for traditional…

Genomics · Quantitative Biology 2024-08-13 Wenwen Min , Zhen Wang , Fangfang Zhu , Taosheng Xu , Shunfang Wang

Clustering aims to group unlabeled objects based on similarity inherent among them into clusters. It is important for many tasks such as anomaly detection, database sharding, record linkage, and others. Some clustering methods are taken as…

Databases · Computer Science 2024-12-02 Binbin Gu , Saeed Kargar , Faisal Nawab

One of the most promising approaches for unsupervised learning is combining deep representation learning and deep clustering. Some recent works propose to simultaneously learn representation using deep neural networks and perform clustering…

Computer Vision and Pattern Recognition · Computer Science 2022-09-07 Mina Rezaei , Emilio Dorigatti , David Ruegamer , Bernd Bischl