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In recent years, the advances in single-cell RNA-seq techniques have enabled us to perform large-scale transcriptomic profiling at single-cell resolution in a high-throughput manner. Unsupervised learning such as data clustering has become…

Genomics · Quantitative Biology 2020-01-07 Shixiong Zhang , Xiangtao Li , Qiuzhen Lin , Ka-Chun Wong

Important tasks in the study of genomic data include the identification of groups of similar cells (for example by clustering), and visualisation of data summaries (for example by dimensional reduction). In this paper, we develop a novel…

Methodology · Statistics 2024-10-15 Thomas E. Bartlett , Swati Chandna , Sandipan Roy

Datasets from single-molecule experiments often reflect a large variety of molecular behaviour. The exploration of such datasets can be challenging, especially if knowledge about the data is limited and a priori assumptions about expected…

Data Analysis, Statistics and Probability · Physics 2020-04-06 Anton Vladyka , Tim Albrecht

Patchwork learning arises as a new and challenging data collection paradigm where both samples and features are observed in fragmented subsets. Due to technological limits, measurement expense, or multimodal data integration, such patchwork…

Methodology · Statistics 2024-06-21 Lili Zheng , Andersen Chang , Genevera I. Allen

In recent years, recommender systems have advanced rapidly, where embedding learning for users and items plays a critical role. A standard method learns a unique embedding vector for each user and item. However, such a method has two…

Artificial Intelligence · Computer Science 2023-02-13 Yizhou Chen , Guangda Huzhang , Anxiang Zeng , Qingtao Yu , Hui Sun , Heng-yi Li , Jingyi Li , Yabo Ni , Han Yu , Zhiming Zhou

We introduce a novel self-supervised deep clustering approach tailored for unstructured data without requiring prior knowledge of the number of clusters, termed Adaptive Self-supervised Robust Clustering (ASRC). In particular, ASRC…

Machine Learning · Computer Science 2024-07-31 Chen-Lu Ding , Jiancan Wu , Wei Lin , Shiyang Shen , Xiang Wang , Yancheng Yuan

Co-clustering exploits the duality of instances and features to simultaneously uncover meaningful groups in both dimensions, often outperforming traditional clustering in high-dimensional or sparse data settings. Although recent deep…

Machine Learning · Computer Science 2025-04-10 Ashwin Vinod , Chandrajit Bajaj

Process discovery algorithms automatically extract process models from event logs, but high variability often results in complex and hard-to-understand models. To mitigate this issue, trace clustering techniques group process executions…

Machine Learning · Computer Science 2025-12-11 Jari Peeperkorn , Johannes De Smedt , Jochen De Weerdt

In this paper, we present a novel method for co-clustering, an unsupervised learning approach that aims at discovering homogeneous groups of data instances and features by grouping them simultaneously. The proposed method uses the entropy…

Machine Learning · Statistics 2017-05-22 Charlotte Laclau , Ievgen Redko , Basarab Matei , Younès Bennani , Vincent Brault

Federated learning (FL) is a distributed model for deep learning that integrates client-server architecture, edge computing, and real-time intelligence. FL has the capability of revolutionizing machine learning (ML) but lacks in the…

Unsupervised domain adaptation aiming to learn a specific task for one domain using another domain data has emerged to address the labeling issue in supervised learning, especially because it is difficult to obtain massive amounts of…

Machine Learning · Computer Science 2019-03-13 Jaeyoon Yoo , Changhwa Park , Yongjun Hong , Sungroh Yoon

We present a discriminative clustering approach in which the feature representation can be learned from data and moreover leverage labeled data. Representation learning can give a similarity-based clustering method the ability to…

Machine Learning · Statistics 2023-02-21 Corinne Jones , Vincent Roulet , Zaid Harchaoui

Unsupervised models can provide supplementary soft constraints to help classify new target data under the assumption that similar objects in the target set are more likely to share the same class label. Such models can also help detect…

Machine Learning · Computer Science 2015-03-13 Ayan Acharya , Eduardo R. Hruschka , Joydeep Ghosh , Badrul Sarwar , Jean-David Ruvini

Coupled learning is a contrastive scheme for tuning the properties of individual elements within a network in order to achieve desired functionality of the system. It takes advantage of physics both to learn using local rules and to…

Soft Condensed Matter · Physics 2024-07-09 Lauren E. Altman , Menachem Stern , Andrea J. Liu , Douglas J. Durian

We introduce and address a novel distributed clustering problem where each participant has a private dataset containing only a subset of all available features, and some features are included in multiple datasets. This scenario occurs in…

Data Structures and Algorithms · Computer Science 2025-10-14 Alessio Maritan , Luca Schenato

We propose a general framework for a collaborative machine learning system to assist bioscience researchers with the task of labeling specific cell identities from microscopic still or video imaging. The distinguishing features of this…

Quantitative Methods · Quantitative Biology 2019-03-25 Greg Bubnis , Steven Ban , Matthew D. DiFranco , Saul Kato

Deep learning has shown remarkable success in the field of clustering recently. However, how to transfer a trained clustering model on a source domain to a target domain by leveraging the acquired knowledge to guide the clustering process…

Machine Learning · Computer Science 2023-10-10 Zheng Zhang , Liang Zhao

This paper examines the effectiveness of combining active learning and transfer learning for anomaly detection in cross-domain time-series data. Our results indicate that there is an interaction between clustering and active learning and in…

Machine Learning · Computer Science 2025-08-07 John D. Kelleher , Matthew Nicholson , Rahul Agrahari , Clare Conran

Co-clustering simultaneously clusters rows and columns, revealing more fine-grained groups. However, existing co-clustering methods suffer from poor scalability and cannot handle large-scale data. This paper presents a novel and scalable…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-20 Zihan Wu , Zhaoke Huang , Hong Yan

Self-evolving agents present a promising path toward continual adaptation by distilling task interactions into reusable knowledge artifacts. In practice, this paradigm remains hindered by two coupled bottlenecks: data inefficiency, where…

Artificial Intelligence · Computer Science 2026-05-12 Feng Xiong , Zengbin Wang , Yong Wang , Xuecai Hu , Jinghan He , Liang Lin , Yuan Liu , Xiangxiang Chu