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We consider the problem of learning a high-dimensional multi-task regression model, under sparsity constraints induced by presence of grouping structures on the input covariates and on the output predictors. This problem is primarily…

Machine Learning · Statistics 2012-05-10 Seunghak Lee , Eric P. Xing

For some special data in reality, such as the genetic data, adjacent genes may have the similar function. Thus ensuring the smoothness between adjacent genes is highly necessary. But, in this case, the standard lasso penalty just doesn't…

Methodology · Statistics 2022-09-29 Xin Xin , Boyi Xie , Yunhai Xiao

This paper deals with the GMANOVA model with a matrix of polynomial basis functions as a within-individual design matrix. The model involves two model selection problems: the selection of explanatory variables and the selection of the…

Methodology · Statistics 2025-10-23 M. Ohishi , I. Nagai , R. Oda , H. Yanagihara

Environmental mixture approaches do not accommodate compositional outcomes, consisting of vectors constrained onto the unit simplex. This limitation poses challenges in effectively evaluating the associations between multiple concurrent…

Methodology · Statistics 2025-03-31 Hachem Saddiki , Joshua L. Warren , Corina Lesseur , Elena Colicino

The identification of predictive biomarkers from a large scale of covariates for subgroup analysis has attracted fundamental attention in medical research. In this article, we propose a generalized penalized regression method with a novel…

Methodology · Statistics 2019-04-29 Chong Ma , Wenxuan Deng , Shuangge Ma , Ray Liu , Kevin Galinsky

The classification of imbalanced data streams, which have unequal class distributions, is a key difficulty in machine learning, especially when dealing with multiple classes. While binary imbalanced data stream classification tasks have…

Machine Learning · Computer Science 2025-06-26 Soheil Abadifard , Fazli Can

The analysis of spatial data from biological imaging technology, such as imaging mass spectrometry (IMS) or imaging mass cytometry (IMC), is challenging because of a competitive sampling process which convolves signals from molecules in a…

Machine Learning · Statistics 2025-09-26 Joaquim Valerio Teixeira , Ed Reznik , Sudpito Banerjee , Wesley Tansey

For investigating the relationship between the star formation rate and gas surface density, we develop a Bayesian linear regression method that rigorously treats measurement uncertainties and accounts for hierarchical data structure. The…

Cosmology and Nongalactic Astrophysics · Physics 2015-06-11 Rahul Shetty , Brandon C. Kelly , Frank Bigiel

Converting electronic health record (EHR) entries to useful clinical inferences requires one to address the poor scalability of existing implementations of Generalized Linear Mixed Models (GLMM) for repeated measures. The major…

Causal variable selection in time-varying treatment settings is challenging due to evolving confounding effects. Existing methods mainly focus on time-fixed exposures and are not directly applicable to time-varying scenarios. We propose a…

There are many settings where researchers are interested in estimating average treatment effects and are willing to rely on the unconfoundedness assumption, which requires that the treatment assignment be as good as random conditional on…

Methodology · Statistics 2018-02-02 Susan Athey , Guido W. Imbens , Stefan Wager

This paper examines LASSO, a widely-used $L_{1}$-penalized regression method, in high dimensional linear predictive regressions, particularly when the number of potential predictors exceeds the sample size and numerous unit root regressors…

Econometrics · Economics 2024-01-17 Ziwei Mei , Zhentao Shi

Air pollution remains a major environmental risk factor that is often associated with adverse health outcomes. However, quantifying and evaluating its effects on human health is challenging due to the complex nature of exposure data. Recent…

Methodology · Statistics 2025-06-02 Soumyakanti Pan , Sudipto Banerjee

Daily environments have profound influence on our health and behavior. Recent work has shown that digital envirotyping, where computer vision is applied to images of daily environments taken during ecological momentary assessment (EMA), can…

Machine Learning · Statistics 2025-05-22 Ya-Yun Huang , Joseph McClernon , Jason A. Oliver , Matthew M. Engelhard

Stability selection represents an attractive approach to identify sparse sets of features jointly associated with an outcome in high-dimensional contexts. We introduce an automated calibration procedure via maximisation of an in-house…

Distributed lag models are useful in environmental epidemiology as they allow the user to investigate critical windows of exposure, defined as the time period during which exposure to a pollutant adversely affects health outcomes. Recent…

Methodology · Statistics 2021-08-02 Joseph Antonelli , Ander Wilson , Brent Coull

Longitudinal analysis is important in many disciplines, such as the study of behavioral transitions in social science. Only very recently, feature selection has drawn adequate attention in the context of longitudinal modeling. Standard…

Methodology · Statistics 2016-10-26 Tingyang Xu , Jiangwen Sun , Jinbo Bi

Objective: The primary goal of this study was to systematically examine the impact of commonly used imbalance handling methods (IHMs) on predictive performance in biomedical binary classification, considering the interplay between model…

Machine Learning · Computer Science 2026-05-15 Jiandong Chen , Lingjie Su , Le Peng , Yash Travadi , Rui Zhang , Ju Sun

We propose a procedure for sparse regression with pairwise interactions, by generalizing the Univariate Guided Sparse Regression (UniLasso) methodology. A central contribution is our introduction of a concept of univariate (or marginal)…

Methodology · Statistics 2026-01-05 Aymen Echarghaoui , Robert Tibshirani

We develop a Bayesian tree ensemble model to estimate heterogeneous treatment effects in censored survival data with high-dimensional covariates. Instead of imposing sparsity through the tree structure, we place a horseshoe prior directly…

Methodology · Statistics 2026-05-08 Tijn Jacobs , Wessel N. van Wieringen , Stéphanie L. van der Pas
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