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We propose PET scanners using low atomic number media that undergo a persistent local change of state along the paths of the Compton recoil electrons. Measurement of the individual scattering locations and angles, deposited energies, and…

Inverse scattering is the process of estimating the spatial distribution of the scattering potential of an object by measuring the scattered wavefields around it. In this paper, we consider reflection tomography of high contrast objects…

Signal Processing · Electrical Eng. & Systems 2020-12-17 Ajinkya Kadu , Hassan Mansour , Petros T. Boufounos

Optical coherence tomography (OCT) has revolutionized retinal disease diagnosis with its high-resolution and three-dimensional imaging nature, yet its full diagnostic automation in clinical practices remains constrained by multi-stage…

Coherent Anti Stokes Raman Scattering (CARS) offers many advantages for nonlinear bio-imaging, thanks to its sub-cellular spatial resolution and unique chemical specificity. Its working principle requires two incident pulsed laser beams…

Endoscopic optical coherence tomography (OCT) is a valuable tool for providing diagnostic images of internal organs and guiding interventions in real time. Miniaturized OCT endoscopes are essential for imaging small and convoluted luminal…

Instrumentation and Detectors · Physics 2023-11-28 Chao Xu , Xin Guan , Syeda Aimen Abbasi , Neng Xia , To Ngai , Li Zhang , Ho-Pui Ho , Sze Hang Calvin Ng , Wu Yuan

A micro-ring-resonator (MRR) optical biosensor based on the evanescent field sensing mechanism has been extensively studied due to its high sensitivity and compact device size. However, a suitable on-chip integrated spectrometer device has…

Optics · Physics 2022-07-19 Kyoung Min Yoo , May Hlaing , Sourabh Jain , James Fan , Yue An , Ray T. Chen

In this work, image analysis techniques used in astrophysics to detect low-contrast signals have been adapted in the processing of Computed Tomography (CT) images, combining Centroidal Voronoi Tessellation (CVT) and machine learning…

Medical Physics · Physics 2025-03-11 Lorenzo Lasagni

Allying high-resolution with a large field-of-view (FOV) is of great importance in the fields of biology and medicine, but particularly challenging when imaging non-flat living samples such as the human retina. Indeed, high-resolution is…

Optical coherence tomography (OCT) is a non-invasive, micrometer-scale imaging modality that has become a clinical standard in ophthalmology. By raster-scanning the retina, sequential cross-sectional image slices are acquired to generate…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Stefan Ploner , Jungeun Won , Julia Schottenhamml , Jessica Girgis , Kenneth Lam , Nadia Waheed , James Fujimoto , Andreas Maier

Compton scatter tomography is an emerging technique with attractive applications in several fields in imaging such as non-destructive testing and medical scanning. In this paper, we introduce a novel modality in three dimensions with a…

Numerical Analysis · Mathematics 2022-03-18 Javier Cebeiro , Cecilia Tarpau , Marcela Morvidone , Diana Rubio , Mai Nguyen

Images with abnormal brain anatomy produce problems for automatic segmentation techniques, and as a result poor ROI detection affects both quantitative measurements and visual assessment of perfusion data. This paper presents a new approach…

Image and Video Processing · Electrical Eng. & Systems 2019-02-19 Svitlana M Alkhimova

Given the potential X-ray radiation risk to the patient, low-dose CT has attracted a considerable interest in the medical imaging field. The current main stream low-dose CT methods include vendor-specific sinogram domain filtration and…

Medical Physics · Physics 2017-12-12 Hu Chen , Yi Zhang , Mannudeep K. Kalra , Feng Lin , Yang Chen , Peixi Liao , Jiliu Zhou , Ge Wang

Limited-angle computed tomography (CT) is often used in clinical applications such as C-arm CT for interventional imaging. However, CT images from limited angles suffers from heavy artifacts due to incomplete projection data. Existing…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Jawook Gu , Jong Chul Ye

Betatron radiation from laser wakefield accelerators is an ultrashort pulsed source of hard, synchrotron-like x-ray radiation. It emanates from a centimetre scale plasma accelerator producing GeV level electron beams. In recent years…

In today's clinics, a cellular-resolution view of the cornea can be achieved only with an in vivo confocal microscope (IVCM) in contact with the eye. Here, we present a common-path Full-field/Spectral-domain OCT microscope (FF/SD OCT),…

Learned Image Compression (LIC) has achieved dramatic progress regarding objective and subjective metrics. MSE-based models aim to improve objective metrics while generative models are leveraged to improve visual quality measured by…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Jixiang Luo , Yan Wang , Hongwei Qin

Recently, an ultra-low-cost linear scan based tomography architecture was proposed by our team. Similar to linear tomosynthesis, the source and detector are translated in opposite directions and the data acquisition system targets on a…

Medical Physics · Physics 2016-10-21 Weiwen Wu , Hengyong Yu , Shaoyu Wang , Fenglin Liu

In this work, we propose to leverage a deep-learning (DL) based reconstruction framework for high quality Swept-Source Optical Coherence Tomography (SS-OCT) images, by incorporating wavelength ({\lambda}) space interferometric fringes.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Maryam Viqar , Erdem Sahin , Violeta Madjarova , Elena Stoykova , Keehoon Hong

Inverse Compton scattering (ICS) can obtain quasi-monochromatic and directional EUV radiation via a MeV-scale energy electron beam and a micron-scale wavelength laser beam, which enables a dramatic reduction in dimension and expense of the…

Accelerator Physics · Physics 2021-05-21 Ruixuan Huang , Qika Jia

Slitless spectrometers can provide simultaneous imaging and spectral data over an extended field of view, thereby allowing rapid data acquisition for extended sources. In some instances, when the object is greatly extended or the spectral…