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Healthcare artificial intelligence systems often degrade in performance when deployed across institutions, with documented performance drops and perpetuation of discriminatory patterns embedded in data. This brittleness comes, in part, from…

Machine Learning · Computer Science 2026-03-30 Munib Mesinovic , Max Buhlan , Tingting Zhu

Identifying variables responsible for changes to a biological system enables applications in drug target discovery and cell engineering. Given a pair of observational and interventional datasets, the goal is to isolate the subset of…

Machine Learning · Computer Science 2025-06-02 Menghua Wu , Umesh Padia , Sean H. Murphy , Regina Barzilay , Tommi Jaakkola

Discovering causal relationship using multivariate functional data has received a significant amount of attention very recently. In this article, we introduce a functional linear structural equation model for causal structure learning when…

Methodology · Statistics 2023-11-01 Saptarshi Roy , Raymond K. W. Wong , Yang Ni

We study a family of regularized score-based estimators for learning the structure of a directed acyclic graph (DAG) for a multivariate normal distribution from high-dimensional data with $p\gg n$. Our main results establish support…

Statistics Theory · Mathematics 2017-10-03 Bryon Aragam , Arash A. Amini , Qing Zhou

Causal representation learning algorithms discover lower-dimensional representations of data that admit a decipherable interpretation of cause and effect; as achieving such interpretable representations is challenging, many causal learning…

Machine Learning · Computer Science 2023-11-09 Elise Walker , Jonas A. Actor , Carianne Martinez , Nathaniel Trask

Understanding the causal relationships between data variables can provide crucial insights into the construction of tabular datasets. Most existing causality learning methods typically focus on applying a single identifiable causal model,…

Machine Learning · Computer Science 2026-04-07 Hristo Petkov , Calum MacLellan , Feng Dong

This paper explores the role of Directed Acyclic Graphs (DAGs) as a representation of conditional independence relationships. We show that DAGs offer polynomially sound and complete inference mechanisms for inferring conditional…

Artificial Intelligence · Computer Science 2013-04-10 Dan Geiger , Judea Pearl

Leveraging labelled data from multiple domains to enable prediction in another domain without labels is a significant, yet challenging problem. To address this problem, we introduce the framework DAPDAG (\textbf{D}omain \textbf{A}daptation…

Machine Learning · Computer Science 2022-08-03 Yanke Li , Hatt Tobias , Ioana Bica , Mihaela van der Schaar

Graphs are expressive abstractions representing more effectively relationships in data and enabling data science tasks. They are also a widely adopted paradigm in causal inference focusing on causal directed acyclic graphs. Causal DAGs…

Databases · Computer Science 2024-12-19 Amedeo Pachera , Mattia Palmiotto , Angela Bonifati , Andrea Mauri

In multivariate time series analysis, understanding the underlying causal relationships among variables is often of interest for various applications. Directed acyclic graphs (DAGs) provide a powerful framework for representing causal…

Methodology · Statistics 2025-07-30 Arkaprava Roy , Anindya Roy , Subhashis Ghosal

Scientists often use directed acyclic graphs (days) to model the qualitative structure of causal theories, allowing the parameters to be estimated from observational data. Two causal models are equivalent if there is no experiment which…

Artificial Intelligence · Computer Science 2013-04-05 Tom S. Verma , Judea Pearl

Statistical relationships in observed data can arise for several different reasons: the observed variables may be causally related, they may share a latent common cause, or there may be selection bias. Each of these scenarios can be…

Statistics Theory · Mathematics 2025-09-30 Ryan Carey , Marina Maciel Ansanelli , Elie Wolfe , Robin J. Evans

Existing approaches to causal discovery often rely on restrictive modeling assumptions that limit their applicability in real-world settings, particularly when data are heavy-tailed or contain a mixture of discrete and continuous variables.…

Methodology · Statistics 2025-11-25 Juraj Bodik , Valérie Chavez-Demoulin

Causal inference is known to be very challenging when only observational data are available. Randomized experiments are often costly and impractical and in instrumental variable regression the number of instruments has to exceed the number…

Methodology · Statistics 2018-06-19 Dominik Rothenhäusler , Peter Bühlmann , Nicolai Meinshausen

We introduce priors and algorithms to perform Bayesian inference in Gaussian models defined by acyclic directed mixed graphs. Such a class of graphs, composed of directed and bi-directed edges, is a representation of conditional…

Methodology · Statistics 2012-07-02 Ricardo Silva , Zoubin Ghahramani

This paper develops new methods for causal inference in observational studies on a single large network of interconnected units, addressing two key challenges: long-range dependence among units and the presence of general interference. We…

Methodology · Statistics 2025-11-24 Jizhou Liu , Dake Zhang , Eric J. Tchetgen Tchetgen

A fundamental challenge of scientific research is inferring causal relations based on observed data. One commonly used approach involves utilizing structural causal models that postulate noisy functional relations among interacting…

Methodology · Statistics 2024-08-13 David Strieder , Mathias Drton

Identifying causal parameters from observational data is fraught with subtleties due to the issues of selection bias and confounding. In addition, more complex questions of interest, such as effects of treatment on the treated and mediated…

Methodology · Statistics 2015-11-17 Ilya Shpitser , Eric Tchetgen Tchetgen

Covariate adjustment is a widely used approach to estimate total causal effects from observational data. Several graphical criteria have been developed in recent years to identify valid covariates for adjustment from graphical causal…

Statistics Theory · Mathematics 2015-07-07 Emilija Perković , Johannes Textor , Markus Kalisch , Marloes H. Maathuis

The recent works on causal discovery have followed a similar trend of learning partial ancestral graphs (PAGs) since observational data constrain the true causal directed acyclic graph (DAG) only up to a Markov equivalence class. This…

Machine Learning · Computer Science 2026-03-03 Tingrui Huang , Devendra Singh Dhami