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As humanity struggles to contain the global Covid-19 infection, prophylactic actions are grandly slowed down by the shortage of testing kits. Governments have taken several measures to work around this shortage: the FDA has become more…
Fast testing can help mitigate the coronavirus disease 2019 (COVID-19) pandemic. Despite their accuracy for single sample analysis, infectious diseases diagnostic tools, like RT-PCR, require substantial resources to test large populations.…
A key requirement in containing contagious diseases, such as the Coronavirus disease 2019 (COVID-19) pandemic, is the ability to efficiently carry out mass diagnosis over large populations. Some of the leading testing procedures, such as…
Respirators provide protection from inhalation exposure to dangerous substances, such as chemicals and infectious particles, including SARS-Covid-laden droplets and aerosols. However, they are prone to exposure to stale air as the masks…
To mitigate the SARS-CoV-2 pandemic, officials have employed social distancing and stay-at-home measures, with increased attention to room ventilation emerging only more recently. Effective distancing practices for open spaces can be…
The acute respiratory distress syndrome (ARDS) is characterized by the acute development of diffuse alveolar damage (DAD) resulting in increased vascular permeability and decreased alveolar gas exchange. Mechanical ventilation is a…
Activities such as singing or playing a wind instrument release respiratory particles into the air that may contain pathogens and thus pose a risk for infection transmission. Here we report measurements of the size distribution, number, and…
Background: Rapid testing for an infection is paramount during a pandemic to prevent continued viral spread and excess morbidity and mortality. This study aimed to determine whether alternative testing strategies based on sample pooling can…
High-resolution large-eddy simulation (LES) is exploited to study indoor air turbulence and its effect on the dispersion of respiratory virus-laden aerosols and subsequent transmission risks. The methodology is applied to assess two…
At the front lines of the world's response to the COVID-19 pandemic are hero-clinicians facing a lack of critical supplies including protective medical grade breathing masks and filtering materials. At the same time, the general public is…
Mechanical ventilation is critical for managing respiratory failure, but inappropriate ventilator settings can lead to ventilator-induced lung injury (VILI), increasing patient morbidity and mortality. Evaluating the causal impact of…
Pooled testing offers an efficient solution to the unprecedented testing demands of the COVID-19 pandemic, although with potentially lower sensitivity and increased costs to implementation in some settings. Assessments of this trade-off…
We propose a robust in-time predictor for in-hospital COVID-19 patient's probability of requiring mechanical ventilation. A challenge in the risk prediction for COVID-19 patients lies in the great variability and irregular sampling of…
In pandemics or epidemics, public health authorities need to rapidly test a large number of individuals, both to determine the line of treatment as well as to know the spread of infection to plan containment, mitigation and future…
With the ongoing COVID-19 pandemic, understanding the characteristics of the virus has become an important and challenging task in the scientific community. While tests do exist for COVID-19, the goal of our research is to explore other…
When testing for a disease such as COVID-19, the standard method is individual testing: we take a sample from each individual and test these samples separately. An alternative is pooled testing (or "group testing"), where samples are mixed…
We show that enhanced turbulent mixing can be used to mitigate airborne COVID-19 transmission by dispersing virus-laden clouds in enclosed, poorly ventilated spaces. A simple system of fan-driven turbulent jets is designed so as to minimize…
We consider a novel method to increase the reliability of COVID-19 virus or antibody tests by using specially designed pooled testings. Instead of testing nasal swab or blood samples from individual persons, we propose to test mixtures of…
In the current COVID19 crisis many national healthcare systems are confronted with an acute shortage of tests for confirming SARS-CoV-2 infections. For low overall infection levels in the population, pooling of samples can drastically…
COVID-19 pandemic is a deadly disease spreading very fast. People with the confronted immune system are susceptible to many health conditions. A highly significant condition is pneumonia, which is found to be the cause of death in the…