Related papers: Splitting one ventilator for multiple patients -- …
Background: Recent pandemic has brought a sudden surge in the requirement of mechanical ventilators all over the world. In this backdrop, there is wide interest in looking for ways to support multiple patients from a single ventilator.…
Mechanical ventilation is used for patients with a variety of lung diseases. Traditionally, ventilators have been designed to monotonously deliver equal sized breaths. While it may seem intuitive that lungs may benefit from unvarying and…
The choice of lung protective ventilation settings for mechanical ventilation has a considerable impact on patient outcome, yet identifying optimal ventilatory settings for individual patients remains highly challenging due to the inherent…
Objective: To develop an algorithm that can infer the severity level of a COPD patient's airflow limitation from tidal breathing data that is collected by a wearable device. Methods: Data was collected from 25 single visit adult volunteers…
Non-invasive estimation of respiratory physiology using computational algorithms promises to be a valuable technique for future clinicians to detect detrimental changes in patient pathophysiology. However, few clinical algorithms used to…
The lack of quantitative risk assessment of airborne transmission of COVID-19 under practical settings leads to large uncertainties and inconsistencies in our preventive measures. Combining in situ measurements and numerical simulations, we…
A variety of optimal control, estimation, system identification and design problems can be formulated as functional optimization problems with differential equality and inequality constraints. Since these problems are infinite-dimensional…
Background: Mechanical ventilation is life-saving for preterm infants with respiratory distress syndrome but can also contribute to lung injury and long-term morbidity. Protective ventilation strategies are recommended, yet implementation…
Controlling the air quality is of the utmost importance in today buildings. Vertical air curtains are often used to separate two different climatic zones with a view to reduce heat transfer. In fact, this research work proposes an air…
COVID-19, a viral respiratory pandemic, has rapidly spread throughout the globe. Large scale and rapid testing of the population is required to contain the disease, but such testing is prohibitive in terms of resources, cost and time.…
Researchers have been battling with the question of how we can identify Coronavirus disease (COVID-19) cases efficiently, affordably and at scale. Recent work has shown how audio based approaches, which collect respiratory audio data…
We propose a novel testing and containment strategy in order to contain the spread of SARS-CoV2 while permitting large parts of the population to resume social and economic activity. Our approach recognises the fact that testing capacities…
Respiratory ailments are increasing globally at an alarming rate and are currently one of the leading factors of death and infirmity worldwide. Among respiratory diseases, those linked to poor air quality and pollutants are increasing at a…
The usual problem for group testing is this: For a given number of individuals and a given prevalence, how many tests T* are required to find every infected individual? In real life, however, the problem is usually different: For a given…
Sample pooling consists in combining samples from multiple individuals into a single pool that is then tested using a unique test-kit. A positive test means that at least one individual within the pool is infected. Here, we propose an…
Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a pandemic of epic proportions and a global response to prepare health systems worldwide is of utmost importance. In addition to its cost-effectiveness in a…
Bubble curtains are widely used to protect marine life from exposure to noise during offshore construction. However, operating a bubble curtain is costly. Therefore optimizing the acoustic effect of the available air is important. An…
The need to understand how infection spreads to the deep lung was acutely realized during the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) pandemic. The challenge of modeling virus laden aerosol transport and deposition in…
Recently, Kami\'nski et al. [1] demonstrated that a two-dimensional streamwise waviness with carefully selected amplitude and period can be effectively used in postponement of a flow separation at high Reynolds number which is out of reach…
This study presents a new risk-averse multi-stage stochastic epidemics-ventilator-logistics compartmental model to address the resource allocation challenges of mitigating COVID-19. This epidemiological logistics model involves the…