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We develop an algorithm capable of imaging a three-dimensional object given a collection of two-dimensional images of that object that are significantly influenced by the curvature of the Ewald sphere. These two-dimensional images cannot be…

Instrumentation and Detectors · Physics 2021-03-02 J. P. J. Chen , K. E. Schmidt , J. C. H. Spence , R. A. Kirian

Cellular Electron Cryo-Tomography (CECT) is a powerful imaging technique for the 3D visualization of cellular structure and organization at submolecular resolution. It enables analyzing the native structures of macromolecular complexes and…

Quantitative Methods · Quantitative Biology 2018-05-16 Chang Liu , Xiangrui Zeng , Ruogu Lin , Xiaodan Liang , Zachary Freyberg , Eric Xing , Min Xu

Optical diffraction tomography measures the three-dimensional refractive index map of a specimen and visualizes biochemical phenomena at the nanoscale in a non-destructive manner. One major drawback of optical diffraction tomography is poor…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 DongHun Ryu , Dongmin Ryu , YoonSeok Baek , Hyungjoo Cho , Geon Kim , Young Seo Kim , Yongki Lee , Yoosik Kim , Jong Chul Ye , Hyun-Seok Min , YongKeun Park

Ultrafast diffraction imaging is a powerful tool to retrieve the geometric structure of gas-phase molecules with combined picometre spatial and attosecond temporal resolution. However, structural retrieval becomes progressively difficult…

Chemical Physics · Physics 2021-10-13 Xinyao Liu , Kasra Amini , Aurelien Sanchez , Blanca Belsa , Tobias Steinle , Jens Biegert

State-of-the-art electron microscopes such as scanning electron microscopes (SEM), scanning transmission electron microscopes (STEM) and transmission electron microscopes (TEM) have become increasingly sophisticated. However, the quality of…

Computational Physics · Physics 2023-03-31 I. Lobato , T. Friedrich , S. Van Aert

Electrical Impedance Tomography (EIT) is a powerful imaging technique with diverse applications, e.g., medical diagnosis, industrial monitoring, and environmental studies. The EIT inverse problem is about inferring the internal conductivity…

Machine Learning · Computer Science 2023-10-31 Derick Nganyu Tanyu , Jianfeng Ning , Andreas Hauptmann , Bangti Jin , Peter Maass

We solve the orientation recovery of a tumbling protein in the gas phase from single-event measurements of the spatial positions of its ions after an X-ray laser induced explosion. We simulate diffracted X-ray signal and ion dynamics under…

Chemical Physics · Physics 2026-03-26 Tomas André , Alfredo Bellisario , Nicusor Timneanu , Carl Caleman

Instrumentation developments in electron energy-loss spectroscopy (EELS) in the scanning transmission electron microscope (STEM) one decade ago paved the way for combining milli-electronvolt energy resolution in spectroscopy with…

Mesoscale and Nanoscale Physics · Physics 2024-10-15 Benedikt Haas , Christoph T. Koch , Peter Rez

High-throughput 2D and 3D scanning electron microscopy, which relies on automation and dependable control algorithms, requires high image quality with minimal human intervention. Classical focus and astigmatism correction algorithms attempt…

Instrumentation and Detectors · Physics 2023-05-10 Philipp Johannes Schubert , Rangoli Saxena , Joergen Kornfeld

A long-standing challenge in tomography is the 'missing wedge' problem, which arises when the acquisition of projection images within a certain angular range is restricted due to geometrical constraints. This incomplete dataset results in…

Materials Science · Physics 2025-03-26 Chonghang Zhao , Mingyuan Ge , Xiaogang Yang , Yong S. Chu , Hanfei Yan

Accurate reconstruction of recoil-electron directions is critical for enhancing the point-spread function of electron-tracking Compton cameras (ETCCs) in gamma-ray imaging. Although full three-dimensional (3D) readout systems achieve…

Instrumentation and Detectors · Physics 2026-04-22 Tomonori Ikeda , Tatsuya Sawano , Naomi Tsuji , Yoshitaka Mizumura

Synchrotron-based x-ray tomography is a noninvasive imaging technique that allows for reconstructing the internal structure of materials at high spatial resolutions from tens of micrometers to a few nanometers. In order to resolve sample…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Zhengchun Liu , Tekin Bicer , Rajkumar Kettimuthu , Doga Gursoy , Francesco De Carlo , Ian Foster

The need for advanced materials has led to the development of complex, multi-component alloys or solid-solution alloys. These materials have shown exceptional properties like strength, toughness, ductility, electrical and electronic…

Phase-shifting electron holography is an excellent method to reveal electron wave phase information with very high phase sensitivity over a large range of spatial frequencies. It circumvents the limiting trade-off between fringe spacing and…

Materials Science · Physics 2024-04-19 J. Lindner , U. Ross , T. Meyer , V. Boureau , M. Seibt , Ch. Jooss

The appearance of direct electron detectors marked a new era for electron diffraction. Their high sensitivity and low noise opens the possibility to extend electron diffraction from transmission electron microscopes (TEM) to lower energies…

Applied Physics · Physics 2025-02-18 Nikita Denisov , Andrey Orekhov , Johan Verbeeck

Optical coherence tomography (OCT) captures cross-sectional data and is used for the screening, monitoring, and treatment planning of retinal diseases. Technological developments to increase the speed of acquisition often results in systems…

Image and Video Processing · Electrical Eng. & Systems 2023-01-03 Timothy T. Yu , Da Ma , Jayden Cole , Myeong Jin Ju , Mirza F. Beg , Marinko V. Sarunic

Tomographic imaging is useful for revealing the internal structure of a 3D sample. Classical reconstruction methods treat the object of interest as a vector to estimate its value. Such an approach, however, can be inefficient in analyzing…

Applications · Statistics 2022-04-06 Sanket R. Jantre , Zichao Wendy Di

Three dimensional electron back-scattered diffraction (EBSD) microscopy is a critical tool in many applications in materials science, yet its data quality can fluctuate greatly during the arduous collection process, particularly via…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Harry Dong , Sean Donegan , Megna Shah , Yuejie Chi

Phase contrast transmission electron microscopy (TEM) is a powerful tool for imaging the local atomic structure of materials. TEM has been used heavily in studies of defect structures of 2D materials such as monolayer graphene due to its…

Materials Science · Physics 2021-09-01 Robbie Sadre , Colin Ophus , Anstasiia Butko , Gunther H Weber

X-ray tomography is capable of imaging the interior of objects in three dimensions non-invasively, with applications in biomedical imaging, materials science, electronic inspection, and other fields. The reconstruction process can be an…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Zhen Guo , Jung Ki Song , George Barbastathis , Michael E. Glinsky , Courtenay T. Vaughan , Kurt W. Larson , Bradley K. Alpert , Zachary H. Levine
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