English

A new solution to the curved Ewald sphere problem for 3D image reconstruction in electron microscopy

Instrumentation and Detectors 2021-03-02 v2 Computer Vision and Pattern Recognition

Abstract

We develop an algorithm capable of imaging a three-dimensional object given a collection of two-dimensional images of that object that are significantly influenced by the curvature of the Ewald sphere. These two-dimensional images cannot be approximated as projections of the object. Such an algorithm is useful in cryo-electron microscopy where larger samples, higher resolution, or lower energy electron beams are desired, all of which contribute to the significance of Ewald curvature.

Keywords

Cite

@article{arxiv.2101.11709,
  title  = {A new solution to the curved Ewald sphere problem for 3D image reconstruction in electron microscopy},
  author = {J. P. J. Chen and K. E. Schmidt and J. C. H. Spence and R. A. Kirian},
  journal= {arXiv preprint arXiv:2101.11709},
  year   = {2021}
}
R2 v1 2026-06-23T22:36:15.665Z