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Cell nuclei segmentation is one of the most important tasks in the analysis of biomedical images. With ever-growing sizes and amounts of three-dimensional images to be processed, there is a need for better and faster segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2017-02-20 Julian Arz , Peter Sanders , Johannes Stegmaier , Ralf Mikut

For the last thirty years, several Dynamic Memory Managers (DMMs) have been proposed. Such DMMs include first fit, best fit, segregated fit and buddy systems. Since the performance, memory usage and energy consumption of each DMM differs,…

Neural and Evolutionary Computing · Computer Science 2024-07-16 José L. Risco-Martín , David Atienza , J. Manuel Colmenar , Oscar Garnica

Triply periodic minimal surface (TPMS) metamaterials characterized by mathematically-controlled topologies exhibit better mechanical properties compared to uniform structures. The unit cell topology of such metamaterials can be further…

Computational Engineering, Finance, and Science · Computer Science 2023-03-20 Asha Viswanath , Diab W Abueidda , Mohamad Modrek , Kamran A Khan , Seid Koric , Rashid K. Abu Al-Rub

Progress in anatomical 3D shape classification is limited by the complexity of mesh data and the lack of standardized benchmarks, highlighting the need for robust learning methods and reproducible evaluation. We introduce two key steps…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Tomáš Krsička , Tibor Kubík

This work studies three multigrid variants for matrix-free finite-element computations on locally refined meshes: geometric local smoothing, geometric global coarsening, and polynomial global coarsening. We have integrated the algorithms…

Numerical Analysis · Mathematics 2022-04-12 Peter Munch , Timo Heister , Laura Prieto Saavedra , Martin Kronbichler

Specialized function gradient computing hardware could greatly improve the performance of state-of-the-art optimization algorithms, e.g., based on gradient descent or conjugate gradient methods that are at the core of control, machine…

This article describes algorithms for the hybrid parallelization and SIMD vectorization of molecular dynamics simulations with short-range forces. The parallelization method combines domain decomposition with a thread-based parallelization…

Materials Science · Physics 2017-09-13 Chris M. Mangiardi , Ralf Meyer

This work develops an algorithm for PDE-constrained shape optimization based on Lipschitz transformations. Building on previous work in this field, the $p$-Laplace operator is utilized to approximate a descent method for Lipschitz shapes.…

Optimization and Control · Mathematics 2023-04-24 Peter Marvin Müller , Jose Pinzon , Thomas Rung , Martin Siebenborn

Large-scale deep learning models contribute to significant performance improvements on varieties of downstream tasks. Current data and model parallelism approaches utilize model replication and partition techniques to support the…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-05-19 Youhe Jiang , Fangcheng Fu , Xupeng Miao , Xiaonan Nie , Bin Cui

A long-standing challenge is designing multi-scale structures with good connectivity between cells while optimizing each cell to reach close to the theoretical performance limit. We propose a new method for direct multi-scale topology…

Neural and Evolutionary Computing · Computer Science 2025-02-21 Hongrui Chen , Xingchen Liu , Levent Burak Kara

This paper presents some of our findings on the scalability of parallel 3D mesh generation on distributed memory machines. The primary objective of this study was to evaluate a distributed memory approach for implementing a 3D parallel…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-08-25 Polykarpos Thomadakis , Nikos Chrisochoides

The effectiveness of a new algorithm, parallel tempering, is studied for numerical simulations of biological molecules. These molecules suffer from a rough energy landscape. The resulting slowing down in numerical simulations is overcome by…

Chemical Physics · Physics 2009-10-30 Ulrich H. E. Hansmann

Data-driven cell tracking and segmentation methods in biomedical imaging require diverse and information-rich training data. In cases where the number of training samples is limited, synthetic computer-generated data sets can be used to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 David Wiesner , Julian Suk , Sven Dummer , Tereza Nečasová , Vladimír Ulman , David Svoboda , Jelmer M. Wolterink

For the numerical solution of shape optimization problems, particularly those constrained by partial differential equations (PDEs), the quality of the underlying mesh is of utmost importance. Particularly when investigating complex…

Optimization and Control · Mathematics 2025-10-14 Sebastian Blauth , Christian Leithäuser

We present an efficient, parallel, constrained optimization technique for approximating CAD curves with super-convergent rates. The optimization function is a disparity measure in terms of a piece-wise polynomial approximation and a curve…

Numerical Analysis · Mathematics 2022-12-05 Julia Docampo Sánchez

Segmentation of microscopy images constitutes an ill-posed inverse problem due to measurement noise, weak object boundaries, and limited labeled data. Although deep neural networks provide flexible nonparametric estimators, unconstrained…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Seema K. Poudel , Sunny K. Khadka

Real-world applications of computational fluid dynamics often involve the evaluation of quantities of interest for several distinct geometries that define the computational domain or are embedded inside it. For example, design optimization…

Numerical Analysis · Mathematics 2023-08-08 Guglielmo Padula , Francesco Romor , Giovanni Stabile , Gianluigi Rozza

We design and implement an efficient parallel algorithm for finding a perfect matching in a weighted bipartite graph such that weights on the edges of the matching are large. This problem differs from the maximum weight matching problem,…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-09-07 Ariful Azad , Aydın Buluc , Xiaoye S. Li , Xinliang Wang , Johannes Langguth

We consider the problem of simultaneously learning to linearly combine a very large number of kernels and learn a good predictor based on the learnt kernel. When the number of kernels $d$ to be combined is very large, multiple kernel…

Machine Learning · Computer Science 2015-03-20 Arash Afkanpour , András György , Csaba Szepesvári , Michael Bowling

This paper presents a synthesis approach in a density-based topology optimization setting to design large deformation compliant mechanisms for inducing desired strains in biological tissues. The modelling is based on geometrical…

Computational Engineering, Finance, and Science · Computer Science 2021-03-26 P. Kumar , C. Schmidleithner , N. B. Larsen , O. Sigmund