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Recent advances in electron microscopy have enabled the imaging of single cells in 3D at nanometer length scale resolutions. An uncharted frontier for in silico biology is the ability to simulate cellular processes using these observed…

Recently, single-stage embedding based deep learning algorithms gain increasing attention in cell segmentation and tracking. Compared with the traditional "segment-then-associate" two-stage approach, a single-stage algorithm not only…

Computer Vision and Pattern Recognition · Computer Science 2021-04-21 Mengyang Zhao , Aadarsh Jha , Quan Liu , Bryan A. Millis , Anita Mahadevan-Jansen , Le Lu , Bennett A. Landman , Matthew J. Tyskac , Yuankai Huo

This article addresses the research question if and how the finite cell method, an embedded domain finite element method of high order, may be used in the simulation of metal deposition to harvest its computational efficiency. This…

Numerical Analysis · Mathematics 2018-09-26 Ali Özcan , Stefan Kollmannsberger , John N. Jomo , Ernst Rank

In the pursuit of designing safer and more efficient energy-absorbing structures, engineers must tackle the challenge of improving crush performance while balancing multiple conflicting objectives, such as maximising energy absorption and…

Materials Science · Physics 2025-02-25 Hirak Kansara , Siamak F. Khosroshahi , Leo Guo , Miguel A. Bessa , Wei Tan

The proposed designs of many auxiliary long-lived particle (LLP) detectors at the LHC call for the instrumentation of a large surface area inside the detector volume, in order to reliably reconstruct tracks and LLP decay vertices. Taking…

High Energy Physics - Phenomenology · Physics 2022-11-21 Thomas Gorordo , Simon Knapen , Benjamin Nachman , Dean J. Robinson , Adi Suresh

Skin lesion detection in dermoscopic images is essential in the accurate and early diagnosis of skin cancer by a computerized apparatus. Current skin lesion segmentation approaches show poor performance in challenging circumstances such as…

Computer Vision and Pattern Recognition · Computer Science 2022-07-26 Pourya Shamsolmoali , Masoumeh Zareapoor , Eric Granger , Huiyu Zhou

This paper presents a method for time-lapse 3D cell analysis. Specifically, we consider the problem of accurately localizing and quantitatively analyzing sub-cellular features, and for tracking individual cells from time-lapse 3D confocal…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Jiaxiang Jiang , Amil Khan , S. Shailja , Samuel A. Belteton , Michael Goebel , Daniel B. Szymanski , B. S. Manjunath

As electronic structure simulations continue to grow in size, the system-size scaling of computational costs increases in importance relative to cost prefactors. Presently, linear-scaling costs for three-dimensional systems are only…

Computational Physics · Physics 2019-07-04 Jonathan E. Moussa , Andrew D. Baczewski

Recently, Deep Neural Networks (DNNs) have recorded great success in handling medical and other complex classification tasks. However, as the sizes of a DNN model and the available dataset increase, the training process becomes more complex…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-02-08 Samson B. Akintoye , Liangxiu Han , Xin Zhang , Haoming Chen , Daoqiang Zhang

For computational fluid dynamics (CFD) applications with a large number of grid points/cells, parallel computing is a common efficient strategy to reduce the computational time. How to achieve the best performance in the modern…

Performance · Computer Science 2018-03-12 Yong-Xian Wang , Li-Lun Zhang , Wei Liu , Xing-Hua Cheng , Yu Zhuang , Anthony T. Chronopoulos

The $hp$-adaptive finite element method (FEM) - where one independently chooses the mesh size ($h$) and polynomial degree ($p$) to be used on each cell - has long been known to have better theoretical convergence properties than either $h$-…

Numerical Analysis · Mathematics 2023-09-14 Marc Fehling , Wolfgang Bangerth

We present a new deep learning approach for matching deformable shapes by introducing {\it Shape Deformation Networks} which jointly encode 3D shapes and correspondences. This is achieved by factoring the surface representation into (i) a…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Thibault Groueix , Matthew Fisher , Vladimir G. Kim , Bryan C. Russell , Mathieu Aubry

The field of deep learning has witnessed a remarkable shift towards extremely compute- and memory-intensive neural networks. These newer larger models have enabled researchers to advance state-of-the-art tools across a variety of fields.…

Machine Learning · Computer Science 2022-07-04 Daniel Nichols , Siddharth Singh , Shu-Huai Lin , Abhinav Bhatele

The objective of this article is to report the parallel implementation of the 3D molecular dynamic simulation code for laser-cluster interactions. The benchmarking of the code has been done by comparing the simulation results with some of…

Computational Physics · Physics 2015-06-16 Amol R. Holkundkar

In the present study, we consider the Extra-Membrane-Intra model (EMI) for the simulation of excitable tissues at the cellular level. We provide the (possibly large) system of partial differential equations (PDEs), equipped with ad hoc…

Numerical Analysis · Mathematics 2024-09-23 Pietro Benedusi , Paola Ferrari , Marius Causemann , Stefano Serra-Capizzano

In this work, we propose a disentangled latent optimization-based method for parameterizing grouped deforming 3D objects into shape and deformation factors in an unsupervised manner. Our approach involves the joint optimization of a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Mostofa Rafid Uddin , Jana Armouti , Umong Sain , Md Asib Rahman , Xingjian Li , Min Xu

Partitioning a graph into blocks of roughly equal weight while cutting only few edges is a fundamental problem in computer science with numerous practical applications. While shared-memory parallel partitioners have recently matured to…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-06 Peter Sanders , Daniel Seemaier

The Cellular Potts Model (CPM) is a widely used simulation paradigm for systems of interacting cells that has been used to study scenarios ranging from plant development to morphogenesis, tumour growth and cell migration. Despite their wide…

Tissues and Organs · Quantitative Biology 2023-12-18 Shabaz Sultan , Sapna Devi , Scott N. Mueller , Johannes Textor

The rapid growth of deep learning models has increased the demand for efficient distributed training strategies. Fully sharded approaches like ZeRO-3 and FSDP partition model parameters across GPUs and apply optimizations such as…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-20 Masahiro Tanaka , Du Li , Umesh Chand , Ali Zafar , Haiying Shen , Olatunji Ruwase

We consider the problem of accurately identifying cell boundaries and labeling individual cells in confocal microscopy images, specifically, 3D image stacks of cells with tagged cell membranes. Precise identification of cell boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2019-09-06 Jiaxiang Jiang , Po-Yu Kao , Samuel A. Belteton , Daniel B. Szymanski , B. S. Manjunath
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